Assuntos
Antropometria , Osteoporose/patologia , Idoso , Estatura , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
A case of treatment of an ovarian adenocarcinoma (stage IIIc of the IFGO) is reported. The patient underwent a maximal tumor reduction followed by polychemotherapy. After this treatment, a 'second-look' laparotomy shows an incomplete remission. An intensive chemotherapy with total abdomen irradiation and protection of medullary toxicity by an autologous bone marrow infusion is performed, with a satisfactory result, without relapse, 16 months after this treatment (or 25 months after the first laparotomy). Reasons which led the authors to perform an autograft and the conditions under which this treatment may be offered are then presented.
Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Transplante de Medula Óssea , Neoplasias Ovarianas/terapia , Adulto , Feminino , Humanos , Neoplasias Ovarianas/tratamento farmacológico , Neoplasias Ovarianas/radioterapia , PrognósticoRESUMO
After having observed homozygotic identical twin brothers who simultaneously suffered from anaplastic bronchial cancer which rapidly led to death in both cases, the authors assess the frequency of such cases. Review of the available literature failed to produce identical observations, although 4 cases of twins suffering from bronchial cancer with differing histologies (3 epidermoidal and 1 bronchiolar-alveolar) were noted. Statistics show that in the area where the observed twins were living, anaplastic cancer occurs each year in 0.39 of 53-year-old men. The cases of these twins therefore support the notion of the role of genetic factors in the determination of bronchial cancer.
Assuntos
Carcinoma Broncogênico/genética , Neoplasias Pulmonares/genética , Gêmeos Monozigóticos , Gêmeos , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de TempoRESUMO
A case involving a gastric carcinoid in association with parathyroid adenoma is reported and the question of a possible link between these two ailments is discussed.
Assuntos
Adenoma , Tumor Carcinoide , Neoplasia Endócrina Múltipla , Neoplasias das Paratireoides , Neoplasias Gástricas , Adulto , Feminino , HumanosRESUMO
In this paper, the authors discuss an occurrence of hepatic sarcoidosis in a female patient from the French Antilles which was unique in how it was detected (during cholecystectomy), its presence in two organs (bronchus and liver) as evidenced histologically, as well as marked immunological disorders and disturbances of liver function tests. With corticosteroid therapy, the liver function tests were normalized, but histological lesions persisted.
Assuntos
Hepatopatias/patologia , Sarcoidose/patologia , Colecistectomia , Feminino , Humanos , Hepatopatias/complicações , Hepatopatias/tratamento farmacológico , Pessoa de Meia-Idade , Prednisolona/uso terapêutico , Sarcoidose/complicações , Sarcoidose/tratamento farmacológico , Cálculos da Bexiga Urinária/complicações , Cálculos da Bexiga Urinária/cirurgiaAssuntos
Fibrossarcoma/patologia , Neoplasias Cutâneas/patologia , Adulto , Feminino , Humanos , Perna (Membro) , Fatores de TempoRESUMO
The detection of progressive sideroblastic anaemia over a period of weeks in a 58 year old woman led to the diagnosis of chronic lead poisoning confirmed by serum lead levels of 2 mg/l. The alimentary origin of the lead poisoning was proved by the finding of high lead levels in the wine which the patient drank excessively. An inquiry at the wine merchant's showed that the local wine was not responsible but that the foreign wine used to fortify the blend had been contaminated. Chronic lead poisoning in alcoholics which has already been widely reported and the demonstration of abnormally high lead levels in wine, rise the problem of regular statutory surveillance of lead levels in alcoholic beverages.
