Rehabilitation Improves Persistent Symptoms of COVID-19: A Nonrandomized, Controlled, Open Study in Brazil.

OBJECTIVE: This study aimed to investigate the effects of an 8-wk face-to-face rehabilitation program on subjects with persistent symptoms of COVID-19 compared with a remote monitoring group. DESIGN: This is clinical, nonrandomized, controlled, and open study. The face-to-face supervised rehabilitation lasted eight consecutive weeks, twice a week. The remote monitoring group received health guidance. The allocation was carried out by preference because of the emergency period without vaccination during the pandemic. Fatigue, dyspnea (Pulmonary Functional Status and Dyspnea Questionnaire), and exercise capacity (Incremental Shuttle Walk Test) were the primary outcome measures. Lung function, functional status (Post-COVID-19 Functional Status), symptoms of anxiety and depression (Hospital Anxiety and Depression Scale), attention (d2-R), memory (Rey's Auditory-Verbal Learning Test), handgrip strength, and knee extensor strength were secondary outcome measures. RESULTS: Thirty-seven subjects (24.3% hospitalized) completed the baseline and final assessment, rehabilitation ( n = 22, 40.8 [SD, 10.0] yrs, 54.5% female), or remote guidance ( n = 15, 45.4 [SD, 10.5] yrs, 40% female). Both groups showed improved fatigue and exercise capacity. Exercise rehabilitation improved dyspnea, anxiety, attention, and short-term memory. CONCLUSIONS: Rehabilitation is essential for dyspnea in subjects with persistent symptoms of COVID-19 while fatigue naturally reverses.

Regulation of Redox Profile and Genomic Instability by Physical Exercise Contributes to Neuroprotection in Mice with Experimental Glioblastoma.

Glioblastoma (GBM) is an aggressive, common brain cancer known to disrupt redox biology, affecting behavior and DNA integrity. Past research remains inconclusive. To further understand this, an investigation was conducted on physical training's effects on behavior, redox balance, and genomic stability in GBMA models. Forty-seven male C57BL/6J mice, 60 days old, were divided into GBM and sham groups (n = 15, n = 10, respectively), which were further subdivided into trained (Str, Gtr; n = 10, n = 12) and untrained (Sut, Gut; n = 10, n = 15) subsets. The trained mice performed moderate aerobic exercises on a treadmill five to six times a week for a month while untrained mice remained in their enclosures. Behavior was evaluated using open-field and rotarod tests. Post training, the mice were euthanized and brain, liver, bone marrow, and blood samples were analyzed for redox and genomic instability markers. The results indicated increased latency values in the trained GBM (Gtr) group, suggesting a beneficial impact of exercise. Elevated reactive oxygen species in the parietal tissue of untrained GBM mice (Gut) were reduced post training. Moreover, Gtr mice exhibited lower tail intensity, indicating less genomic instability. Thus, exercise could serve as a promising supplemental GBM treatment, modulating redox parameters and reducing genomic instability.

Post-viral fatigue in COVID-19: A review of symptom assessment methods, mental, cognitive, and physical impairment.

Coronavirus 2 is responsible for Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), and the main sequela is persistent fatigue. Post-viral fatigue is common and affects patients with mild, asymptomatic coronavirus disease-2019 (COVID-19). However, the exact mechanisms involved in developing post-COVID-19 fatigue remain unclear. Furthermore, physical and cognitive impairments in these individuals have been widely described. Therefore, this review aims to summarize and propose tools from a multifaceted perspective to assess COVID-19 infection. Herein, we point out the instruments that can be used to assess fatigue in long-term COVID-19: fatigue in a subjective manner or fatigability in an objective manner. For physical and mental fatigue, structured questionnaires were used to assess perceived symptoms, and physical and cognitive performance assessment tests were used to measure fatigability using reduced performance.

Fisioterapia associada à yoga e musicoterapia na doença de Parkinson: ensaio clínico / Physiotherapy associated with yoga and musicotherapy in Parkinson's disease: clinical trial

Introdução: Abordagens alternativas para o exercício físico na doença de Parkinson estão sendo estudadas. Objetivo: Verificar a efetividade da prática em grupo da fisioterapia associada à yoga e musicoterapia nas variáveis cognição, equilíbrio, mobilidade e independência funcional em pessoas com doença de Parkinson. Materiais e Métodos: Sob um ensaio clínico randomizado controlado, realizado na Associação de Parkinson Tocando em Frente, vinte e quatro indivíduos nos estágios leve a moderado da doença de Parkinson foram alocados em grupo controle (GC) e grupo experimental (GE). Os pacientes foram avaliados no início e ao fim do programa de reabilitação de frequência semanal única (16 sessões). Ambos os grupos realizaram fisioterapia e o GE além da fisioterapia, realizou yoga e musicoterapia. Utilizou-se para comparação os testes t de Student e ANOVA two-way (medidas repetidas). Resultado: Fisioterapia associada à yoga e musicoterapia resultou em efeito significante superior na cognição e mobilidade quando comparado à fisioterapia como única intervenção, confirmado pela significante interação entre grupo e momento para as pontuações do Mini-Exame do Estado Mental (p=0,04; ƞ2Æ¿=0,33) e tempo para realização do teste de levantar e andar cronometrado (TUG) (p=0,005; ƞ2Æ¿=0,555) e do TUG com tarefa motora adicional (p=0,00; ƞ2Æ¿=0,924). Conclusão: O programa de reabilitação associando as intervenções realizadas em grupo e com frequência semanal única foi efetivo melhorando as variáveis estudadas, podendo ser utilizado na prática clínica. REBEC: RBR­4kf8zv. (AU)

Introduction: Alternative approaches to exercise in Parkinson's disease are being studied. Objective: Verify the effectiveness of the practce in physical therapy group associated with yoga and music therapy on cognitive, balance, mobility and functional independence variables in people with Parkinson's disease. Materials and Methods: Under a randomized controlled clinical trial, performed in Associação de Parkinson Tocando em Frente, twenty-four individuals in mild to moderate stages of Parkinson's disease were divided into control group (CG) and experimental group (EG). Patients were assessed at baseline and at the end of one weekly frequency rehabilitation program (16 sessions). Both groups performed physical therapy and GE addition to physical therapy, underwent yoga and music therapy. It was used to compare the Student t test and two-way ANOVA (repeated measures). Results: Physiotherapy associated with yoga and music therapy had a higher significant effect on cognition and functional mobility compared to physical therapy as a single intervention, confirmed by the significant interaction between group and time for the scores of Mini-Mental State Examination (p = 0.04; ƞ2Æ¿ = 0.33) and time to perform the timed up and go test (TUG) (p = 0.005; ƞ2Æ¿ = 0.555) and TUG with additional motor task (p = 0.00; ƞ2Æ¿ = 0.924). Conclusion: The rehabilitation program involving the interventions group and one weekly frequency was effective in improving the variables studied, may be embedded in clinical practice. REBEC: RBR­4kf8zv. (AU)

Pilates Exercise for Hypertensive Patients: A Review of the Literature.

Systemic arterial hypertension (SAH) has a prevalence of approximately 1 billion cases worldwide. The main goals for its treatment involve changes in a patient's lifestyle, with a strategy of management that aims to increase his or her level of physical activity, with a recommendation for aerobic and resistance exercise. Some evidence has suggested that training with isometric exercises can produce effects similar to aerobic exercise on blood pressure reduction. Conventional exercises that are currently used in rehabilitation of hypertensive patients show low adherence, with a lack of motivation on the part of those patients. In that context, the Pilates method, which uses isometric exercises, has been gaining in popularity and worldwide acceptance, and it has the potential to be an effective method. The current literature review shows the possible benefits of the Pilates method for rehabilitation of hypertensive patients. However, even though the method is a promising modality, the authors have found that future research appears to be necessary to evaluate the benefits of Pilates for hypertensive patients.

Proposta de um programa de prática em grupo composto por fisioterapia, yoga e musicoterapia para pacientes com doença de Parkinson / Proposal for a programme of practice in group composed of physical therapy, yoga and musictherapy for patients with Parkinson´s disease

OBJETIVO: Analisar os benefícios da prática em grupo da fisioterapia, yoga e musicoterapia nas variáveis progressão da doença, equilíbrio, mobilidade funcional e independência funcional em pessoas com DP. MÉTODOS: Ensaio clínico não controlado, composto por dez indivíduos (4 homens e 6 mulheres) com média de idade de 62,6±9,12 anos, tempo médio de evolução da doença de 89,4±39,64 meses e classificados entre os estágios 1 e 3 da escala de Hoehn e Yahr. Os pacientes foram avaliados no início e ao fim de um programa de prática em grupo com frequência semanal única, totalizando 24 sessões, associando a fisioterapia, yoga e musicoterapia. Análises de comparação dos momentos pré e pós-intervenção por meio do teste de Wilcoxon (nível de significância de 5%). RESULTADOS: Resultados positivos estatisticamente significantes entre a avaliação pré e pós-intervenção foram verificados na progressão da doença (32,5 vs. 28,11), função cognitiva (25,37 vs. 26,50), equilíbrio (50 vs. 53,7), mobilidade funcional realizando a marcha como tarefa única (12,42 vs. 10,18) e com adição de tarefa cognitiva (16,25 vs. 12,5) e independência funcional (34,5 vs. 39). CONCLUSÃO: O programa de prática de grupo aplicado foi benéfico nos desfechos progressão da doença, equilíbrio, mobilidade e independência funcional.

OBJECTIVE: To analyze the benefits of group practice of physical therapy, yoga and music therapy in disease progress variables, balance, functional mobility and functional independence in persons with PD. METHODS: Clinical trial uncontrolled, composed of ten subjects (4 men and 6 women) with a mean age of 62.6 ± 9.12 years, average duration of the 89.4 ± 39.64 months and disease classified among stages 1 and 3 of the Hoehn and Yahr scale. Patients were assessed at baseline and at the end (after 6 months) of a single weekly flight group practice program, totaling 24 sessions, involving physical therapy, yoga and music therapy. Comparative analysis of pre- and post-intervention using the Wilcoxon test (5% significance level). RESULTS: Statistically significant positive results between the pre- and post-intervention were observed in disease progression (32.5 vs. 28.11), cognitive function (25.37 vs. 26.50), balance (50 vs. 53,7), functional mobility performing the march as a single task (12.42 vs. 10.18) and adding cognitive task (16.25 vs. 12.5) and functional independence (34.5 vs. 39). CONCLUSION: The group practice program was beneficial outcomes in disease progression, balance, mobility and functional independence.

Prevalência de incontinência urinária entre idosos institucionalizados e sua relação com o estado mental, independência funcional e comorbidades associadas / Prevalence of urinary incontinence among institutionalized elderly and its relationship to mental state, functional independence, and associated comorbidities

Incontinência urinária é definida como a perda involuntária de urina pela uretra podendo causar diversos problemas sociais e higiênicos, além de alterações que comprometem o convívio social como depressão, vergonha e isolamento, tendo maior prevalência nas mulheres do que nos homens. Objetivos: Determinar a prevalência de incontinência urinária em uma amostra de idosos institucionalizados e analisar sua relação com características sociodemográficas, comorbidades associadas, função cognitiva e independência funcional. Métodos: Estudo transversal, descritivo e exploratório. Participaram 27 idosos que atenderam aos critérios de inclusão, de ambos os sexos, residentes em uma instituição de longa permanência. Prevalência foi determinada pela porcentagem de idosos que apresentaram incontinência urinária; características sociodemográficas e comorbidades avaliadas através de uma ficha de anamnese padrão, revisados com os dados dos prontuários; função cognitiva avaliada através do Mini-Exame do Estado Mental e independência funcional através da escala de Barthel modificada. Comparação entre grupos - teste t de Student e associações - teste do qui-quadrado. Resultados: Nove idosos (33,33%) apresentaram incontinência urinária. Houve associação entre sexo e incontinência urinária, com prevalência maior para o sexo feminino (p = 0,029). A incontinência urinária possui associação com a baixa escolaridade (p = 0,014), o tempo de admissão na instituição (p = 0,004), classificação funcional (p = 0,003) e déficit cognitivo (p = 0,001). Conclusão: Incontinência urinária é frequente em idosos residentes em instituições de longa permanência, com maior prevalência no sexo feminino, havendo relação com a baixa escolaridade, maior tempo de admissão, maior dependência na realização das atividades e pior déficit cognitivo.

Urinary incontinence is defined as the involuntary loss of urine through the urethra, which may cause many social and hygienic problems and changes that compromise social life such as depression, shame, and isolation, with higher prevalence in women than in men. Objectives: To determine the prevalence of urinary incontinence in a sample of institutionalized elderly and analyze its relationship with sociodemographic characteristics, comorbidities, cognitive function, and functional independence. Methods: Cross-sectional, descriptive, and exploratory study. It included 27 seniors of both genders, living in a long-term care facility who met the inclusion criteria. Prevalence was determined by the percentage of elderly patients with urinary incontinence; sociodemographic characteristics and comorbidities were evaluated through a standard history record, reviewed with data from medical records; cognitive function was assessed using the Mini-Mental State Examination, and functional independence was assessed using the modified Barthel scale, while the comparison between groups was made through the Student t test and the associations, through the chi-square test. Results: Nine subjects (33.33%) had urinary incontinence. There was an association between gender and urinary incontinence, with higher prevalence for females (p = 0.029). Urinary incontinence was associated with low educational level (p = 0.014), time at the institution (p = 0.004), functional classification (p = 0.003), and cognitive impairment (p = 0.001). Conclusion: Urinary incontinence is common in elderly residents in long term care facilities, with a higher prevalence in women and was associated with low education, longer time at the institution, greater dependence in performing activities, and greater cognitive impairment.

Benefits of Hip Hop Dance for obese children and adolescents: A systematic review / Hip Hop como atividade física para crianças e adolescentes obesos: Uma revisão sistemática

The infant juvenile obesity is currently one of the most serious public health problems of the 21st century, being directly related to physical inactivity as a decisive factor in the worldwide epidemic. The programs of conventional workouts have become not so attractive for this particular population. Because of that the access and permanence in those structured physical activity programs for obese adolescents are difficult. This systematic review has the general goal to verify what benefits the systematic practice of hip hop dance, can promote in obese children and adolescents. The search for relevant articles was conducted in the electronic databases Medline (Pubmed), Cochrane, LILACS, SciELO from January through June 2014, being structured as [(hip hop /) and (obesity /) and (children/ adolescent), controlled and randomized trials were included regarding the systematic practice of hip hop dance as exercise and its benefits for obese children and adolescents, subjects aged 2-19, considered obese and/or overweight. A total of 21 articles were identified in the survey. Based on the found eligible articles for the full review, only one article met all the inclusion criteria. This preliminary study is intended to broaden the context in health for adolescents and children suffering from overweight and/or obesity, recommending an intervention through dance hip hop, it would be an important modality association for possible monitoring and reducing the risk of associated comorbidities. In this field of research, there is a lack of studies of high methodological quality, which may be able to demonstrate the benefits of this type of intervention.

A obesidade juvenil infantil é atualmente um dos mais graves problemas de saúde pública do século 21, estando diretamente relacionada à inatividade física como um fator decisivo na epidemia mundial. Os programas de exercícios convencionais tornaram-se não tão atrativos para essa população específica. Por conta disto o aceso e permanência em programas de atividade física estruturados para adolescentes obesos são difíceis. Esta revisão sistemática tem o objetivo geral de verificar quais os benefícios que a prática sistemática de dança hip hop, pode promover em crianças e adolescentes obesos. A busca de artigos científicos foi realizada nas bases Medline eletrônica (Pubmed), Cochrane, LILACS, SciELO, de janeiro a junho de 2014, que está sendo estruturado como [(hip hop /) e (obesidade /) e (crianças / adolescentes), estudos controlados e randomizados foram incluídos que investigassem à prática sistemática da dança hip hop como exercício e seus benefícios para crianças e adolescentes obesos, indivíduos com idades entre 2-19, considerados obesos e / ou excesso de peso. Um total de 21 artigos foram identificados na pesquisa. Com base nos artigos encontrados elegíveis para a revisão completa, apenas um artigo cumpriu todos os critérios de inclusão. Este estudo preliminar destina-se a ampliar o contexto em saúde para adolescentes e crianças que sofrem de excesso de peso e / ou obesidade, recomendando uma intervenção através da dança hip hop, como uma importante modalidade que pode ser associada no monitoramento e redução do risco de comorbidades associadas. Neste campo de pesquisa, há uma carência de estudos de alta qualidade metodológica, capzes de demonstrar os benefícios deste tipo de intervenção.