Disparities in Cardiovascular Risk Factors in Northern Plains American Indians Undergoing Coronary Artery Bypass Grafting.

Objectives: Heart disease is the leading cause of death in American Indians (AIs). For AI patients with severe coronary artery disease requiring coronary artery bypass graft (CABG) surgery, little data exist. The purpose of this study was to evaluate short-term outcomes of Northern Plains AI undergoing CABG and identify variations in patient presentation. Methods: All patients undergoing isolated CABG between June 2012 and June 2017 were studied. Seventy-four AI and 1236 non-American Indian (non-AI) patients were identified. Risk factors, preoperative characteristics, cardiac status, procedural information, and outcomes were collected. Univariate analysis comparing short-term clinical outcomes between AI and non-AI populations was performed. Multivariable logistic regression models were constructed and outcome differences assessed. Unadjusted Kaplan-Meier survival estimates were produced using 5-year survival data. Results: AI patients presented with increased risk factors, including higher rates of diabetes mellitus (AI 63.5% vs. non-AI 38.7% p=< 0.001) and smoking/tobacco use (AI 60.8% vs. non-AI 20.0% p=> 0.001). Seventy-nine percent of AI patients resided on or near federal reservations and presented from rural locations. Internal mammary artery (IMA) graft use in both groups was high (AI 95.9% vs. non-AI 94.9% p=0.904), and multiarterial grafting with left internal mammary artery and radial artery use was common in both groups (AI 67.6% vs. non-AI 69.6% p=0.814). No significant differences in unadjusted 30-day mortality or short-term outcomes were detected. Adjusted Kaplan-Meier survival curves were similar between race groups up through 5 years after CABG (p-value=0.38). Conclusion: AIs presented with significantly more risk factors for cardiovascular disease compared with the general population, with especially high rates of insulin-dependent diabetes and active tobacco use. Despite this, outcomes were similar between groups. In propensity-matched groups, AIs were at decreased risk for prolonged length of stay and combined morbidity/mortality. In contrast to previous reports, AI racial identity did not adversely affect survival up to 5 years after CABG.

Mitral Valve Repair Outcomes in a Community Hospital: A Retrospective Analysis.

BACKGROUND: The results of mitral valve repair operations conducted at community hospitals in rural states are not well studied or reported in the literature. METHODS: We retrospectively assessed consecutive patients who underwent isolated mitral valve repair operations performed by a single experienced cardiothoracic surgeon at a large community hospital from May 1, 2006 - April 30, 2010. Patients were monitored for up to three years (average 2.2 years) following surgery for a variety of surgical variables, including morbidity, mortality, and serial two-dimensional transthoracic echocardiographic findings. Comparisons were made with the Society of Thoracic Surgeons Adult Cardiac Surgery Database (ACSD). RESULTS: Sixty-three consecutive patients underwent isolated complex mitral repair operations. Echocardiographic and morbidity data demonstrated successful outcomes, with no operative mortality and a single cardiac-related death within three years postoperatively. Other variables, especially those that relate to post-repair outcomes, showed no significant differences between our patients and comparison data from the ASCD. CONCLUSIONS: Our study demonstrates equivalent risks and outcomes for complex mitral valve repair performed in a community hospital setting as those found in a national database. The appropriate institutional setting for performing highly complex procedures has substantial implications for health policy, especially regarding access and quality issues.

Novel oral anticoagulants vs warfarin for the management of postoperative atrial fibrillation: clinical outcomes and cost analysis.

BACKGROUND: The novel oral anticoagulants (NOACs) apixaban, rivaroxaban, and dabigatran are indicated for the treatment of nonvalvular atrial fibrillation, but their use in patients with postoperative atrial fibrillation (POAF) is less well defined. METHODS: All patients undergoing isolated coronary artery bypass grafting from 2013 to 2015 (n = 598) were studied. Patients with POAF anticoagulated with either warfarin or NOACs were evaluated for differences in length of stay, blood product use, bleeding, and cost of therapy. RESULTS: There was no significant difference between the NOAC and warfarin group for any of the clinical outcomes evaluated. Time to therapeutic anticoagulation was significantly longer with warfarin. Neither group had a major bleeding event during the initial hospitalization, but 2 patients in the warfarin group had delayed major bleeding complications. Total costs were significantly reduced in patients treated with NOACs. CONCLUSIONS: Both NOACs and warfarin are safe and effective means of anticoagulation for POAF after coronary artery bypass grafting. Patients were therapeutic more rapidly and with less cost of treatment when NOACs were used.

Cost-effective endoscopic radial artery harvesting.

Radial artery harvesting has been routinely performed by endoscopy. We present a reduced cost technique using a reusable retractor and thermal welding shears. The combination of reusable and disposable tools allows patients to benefit from endoscopic radial artery harvesting with decreased morbidity and favorable cosmetic results.

Radial artery harvest using endoscopic techniques.

BACKGROUND: Endoscopic vessel harvest for coronary artery bypass conduit has become a routine procedure. With the advancement of endoscopic equipment, radial arteries can be safely harvested with excellent cosmetic results. METHODS: One hundred consecutive patients undergoing coronary artery bypass grafting underwent endoscopic radial artery harvest without complications requiring intervention. The vessel was accessed through a 3-cm long, longitudinal incision performed several millimeters medial to the palpated artery to avoid the lateral antebrachial cutaneous nerve. Commercially available endoscopic retractors, using ultrasonic or direct-current shears, were used to ligate side branches and mobilize the pedicled artery and satellite veins. Ligation was performed with clips at the wrist, endo-loops proximally, and endoshears for transection. RESULTS: Patient age ranged from 42 to 88 years; 70% of the patients were men, and 26% were diabetic. Le f t radial arteries were preferentially harvested. All arteries were used and no further conduit was needed because of inadequate length. In 2 patients subcutaneous hematomas formed postoperatively and resolved without exploration. Although some thenar dysthesia was present in 14 patients, no permanent neurovascular injuries occurred. There were no infections, although skin edges did get traumatized from the retractor. COMMENT: Radial arteries can be harvested in a reproducible, safe, and efficient manner wi th less morbidity and better patient satisfaction.