Endodontical treatment of periapical tooth injury with photodynamic therapy: Case report.

This article describes the use of Photodynamic Therapy (PDT) during the endodontic treatment of teeth with periapical lesion. Patients presented tooth 35 with diagnostic hypotheses of Periapical Cyst or Granuloma. The Crown-Down preparation was performed with the HyFlex CM system. In case I it was not possible to reach the working length, in case II the foraminal debridement was performed at the actual tooth length. In the final irrigation, the E1 - Irrisonic ultrasonic insert was used, promoting sequentially agitation of NaOCl 2.5%, EDTA 17% and NaOCl 2.5%. Then, PDT was applied with 0.005% methylene blue dye. Calcium Hydroxide with Parammonochlorophenol was used and after 15 days, the final irrigation protocol and PDT were performed again. After 90 days of case I and 1 year of case II, the total lesion regression was observed in both cases. It is concluded that the proposed treatment improved the microbial disinfection favoring the regression of the periapical alterations providing satisfactory clinical and radiographic results.

The Influence of Age, Gender, Mandibular Bone Height, Previous Experience with Prostheses, and Fabrication Methods on Masticatory Performance of Complete Denture Wearers.

PURPOSE: To evaluate the influence of age, gender, mandibular bone height, previous experience with prostheses, and methods for denture fabrication on masticatory performance of complete denture (CD) wearers. MATERIALS AND METHODS: For this study, 29 individuals treated with CDs fabricated by simplified or conventional methods had their masticatory performance assessed 4 weeks after the prostheses' adjustment and control, using the sieve method and almonds as a natural food test. Experimental variables related to age, gender, and previous use of complete dentures were collected from dental records. Panoramic digital radiographs were used to determine mandibular bone height according to the criteria described by the American College of Prosthodontists. Data on masticatory performance were assessed using t-test for independent samples to make comparison between simplified and conventional methods, and a multiple linear regression analysis was performed to evaluate the influence of age, gender, previous experience with CDs, and mandibular bone height on masticatory performance using SPSS software with a significance level of 5%. RESULTS: There was no significant influence regarding the method for CD fabrication (p = 0.92), age (p = 0.36), mandibular bone height (p = 0.37), and previous experience with prostheses (p = 0.15) on masticatory performance of CD wearers. Female patients presented lower masticatory performance than male (p = 0.04) patients did. CONCLUSIONS: Considering the limitations of this study, it was concluded that gender might be considered a risk factor for masticatory performance of CD wearers. Female patients demonstrated reduced masticatory performance in comparison to male patients.

Efficacy of lumiracoxib versus diclofenac sodium in pain control following extraction of impacted lower third molar / Eficacia de lumiracoxib frente a diclofenaco de sodio en el control del dolor después de la extracción de un tercer molar inferior impactado

The aim of this paper was to compare the efficacy of two different anti-inflammatory agents, Diclofenac (Deltaflogin®) and Lumiracoxib (Prexige®) in the control of postoperative pain that results from surgical removal of impacted lower third molars. Twenty adult patients from the Oral and Maxillofacial Surgery Division of the Araraquara Dentistry School, UNESP who presented bilateral impacted lower third molars were included in the study. Removal of the impacted teeth was performed in each side in different operative moments in a split mouth design for the study. The anti-inflammatory drugs evaluated were randomly administered on the first and second surgical procedures. The pain level was recorded using an analogical visual scale at 6, 24, 48 and 72 hours after surgical intervention. Both lumiracoxib 400 mg and diclofenac 100 mg are efficient for acute pain control after surgical removal of impacted lower third molars. However, lumiracoxib offered better pain control.

El objetivo de este trabajo fue comparar la eficacia de dos agentes antiinflamatorios distintos, Diclofenaco (Deltaflogin®) y Lumiracoxib (Prexige®) en el control del dolor postoperatorio resultante de la extracción quirúrgica de terceros molares inferiores impactados. Fueron incluídos, veinte pacientes adultos de la División de Cirugía Oral y Maxilofacial de la Escuela de Odontología de Araraquara, UNESP que presentaron terceros molares inferiores impactados. La extracción de los dientes impactados se realizó en distintos tiempos operatorios a cada lado en un diseño de estudio de boca dividida. Los antinflamatorios evaluados fueron administrados de forma aleatoria en el primer y segundo procedimento quirúrgico. El nivel de dolor se registró utilizando una escala visual análoga a las 6, 24, 48 y 72 horas después de la intervención. Ambos; lumiracoxib 400 mg y diclofenaco 100 mg son eficientes para el control del dolor agudo, después de la extracción quirúrgica de terceros molares inferiores impactados. Sin embargo, lumiracoxib ofreció mejor control del dolor.

Efeitos dos parâmetros de digitalização na qualidade da imagem radiográfica periapical com relação a reparos anatômicos / Effect of digitization parameters on periapical radiographic image quality with regard to anatomic landmarks

O objetivo deste estudo foi avaliar a influência dos parâmetros de digitalização na qualidade da imagem radiográfica digital, com relação a reparos anatômicos. Para isso, imagens radiográficas foram digitalizadas por meio de um scanner (n = 160) com resoluções de 300, 600 e 2400 dpi. As imagens de 2400 dpi foram ainda diminuídas para 300 e 600 dpi antes do armazenamento. As digitalizações foram realizadas com e sem máscaras pretas utilizando-se escalas de cinza de 8-bit e 16-bit e salvas em formato tiff. Para avaliar a influência dos parâmetros dedigitalização na qualidade da imagem radiográfica digitalizada, quatro reparos anatômicos foram classificados por dois observadores (muito boa, boa, moderada, regular, pobre) em duas ocasiões diferentes. As concordâncias intra e inter-observadores foram avaliadas por meio do teste Kappa. Os resultados obtidos demonstraram que as concordâncias intra e inter-observadores variaram em função dos reparos anatômicos e da resolução utilizada. A junção cemento esmalte foi o reparo anatômico que apresentou a mais pobre concordância. A utilização da máscarapreta favoreceu a qualidade da imagem digitalizada e seu uso é necessário para cobrir a radiografia durante o processo de digitalização. Portanto, a concordância variou de regular a moderada para a avaliação intra-observador e de regular a pobre para a concordância inter-observador.

The aim of this study was to evaluate the influence of digitization parameters on periapical radiographic image quality, with regard to anatomic landmarks. digitized images (n = 160) were obtained using a flatbed scanner with resolutions of 300, 600 and 2400 dpi. the radiographs of 2400 dpi were decreased to 300 and 600 dpi before storage. Digitizations were performed with and without black masking using 8-bit and 16-bit grayscale and saved in tiff format. Four anatomic landmarks were classified by two observers (very good, good, moderate, regular, poor), in two random sessions. Intraobserver and interobserver agreements were evaluated by Kappa statistics. Inter andintraobserver agreements ranged according to the anatomic landmarks and resolution used. The results obtained demonstrated that the cement enamel junction was the anatomic landmark that presented the poorest concordance. The use of black masking provided better results in the digitized image. the use of a mask to cover radiographs during digitization is necessary. therefore, the concordance ranged from regular to moderate for the intraobserver evaluation and concordance ranged from regular to poor for interobserver evaluation.

Avaliação in vitro do metabolismo de celulas imortalizadas de linhagem odontoblástica MDPC-23 submetidas à aplicação do laser de baixa potência / In vitro evaluation of the metabolism of the immortalized odontoblast-like cells MDPC-23 submitted to the low power laser therapy

Desde que o laser interage com os tecidos, agindo como biomodulador e bioestimuladordo processo de reparação, é de se esperar que a terapia com a luz laser possa, de alguma maneira,estimular o metabolismo dos odontoblastos, ativando a síntese de proteínas específicas. Objetivo:avaliar a atividade metabólica das células odontoblastóides MDPC-23 ante à estimulação comlaser de baixa intensidade. Material e Método: Células MDPC-23 foram cultivadas em situaçãonormal ou associadas à deficiência nutricional parcial (baixas concentrações de soro fetal bovino- 2,5 e 5%), e, então, foram submetidas à aplicação de luz laser com comprimentos de onda de 830nm no infravermelho (AsGaAl) e de 685 nm na luz visível (InGaAlP), ambos emitindo radiaçãocontínua e pontual. Finalmente, o metabolismo dessas células foi avaliado pelo teste de MTT, sendoos valores numéricos obtidos submetidos à análise estatística. Resultado: Foi demonstrado que,de acordo com os padrões de irradiação utilizados para este experimento, não houve um aumentosignificante no metabolismo celular. Conclusão: Foi possível concluir, dentro das condiçõesexperimentais, que o metabolismo das células odontoblastóides MDPC-23 é biomodulado pelolaser vermelho e infravermelho próximo quando essas células são colocadas em estado de estressepor deficiência nutricional.

Since the laser light acts as bio-modulator and bio-stimulator of the healing process,one may expect that a specific laser therapy could also stimulate the odontoblasts to synthesizeand deposit dentinal matrix in order to prevent in vivo dentinal sensitivity. Objective: The aimof this study was to evaluate the metabolic activity of an odontoblast-cell line (MDPC-23)submitted to the low power laser therapy. Material and Methods: MDPC-23 cells were platted(3 x 104 cells/cm2) and incubated with complete medium (10% fetal bovine serum – FBS) orwith nutritional deficiency (2.5% FBS or 5% FBS) in order to simulate stress conditions for theMDPC-23 cells. The cells were suibmitted to the laser irradiation by using wave lengths of 830 nmin the infra-red ray (AsGaAl) or 685 nm in the visible light (InGaAlP), both emitting continuousand punctual radiation. Finally, the cell metabolism was evaluated by the MTT assay and thenumerical scores obtained were submitted to the statistical analysis. Results: It was demonstratedthat the standardized experimental techniques of irradiation employed in this experiment causedno significant increase in the cell metabolism. Conclusion: According to the experimental conditions, it was possible to conclude the metabolism of the MDPC-23 odontoblastic-like cellsis bio-modulated by the red laser and next infra-red ray when these cells are in stress conditioninduced by nutritional deficiency.