Can cyanotoxins penetrate human skin during water recreation to cause negative health effects?

Cyanobacteria blooms and associated cyanotoxins pose significant public health risks during water recreation. Oral ingestion is the only recognized route of toxin exposure in water recreation guidelines. This review examines human skin as a barrier for the prevention of cyanotoxin absorption and investigates the likelihood of negative health effects through dermal exposure. Epidemiological studies of health effects from recreational exposure to algal blooms and toxins are summarized to highlight the importance of better understanding the toxicological effect of dermal exposure. The ability of a specific cyanotoxin to penetrate human skin is inferred by its physiochemical properties according to transdermal drug studies. The review identifies a disparity between the human health effects described in algal bloom exposure case studies and the toxicological skin exposure data. Skin penetration by algal toxins is likely and deserves further investigation.

Alterations of the human skin microbiome after ocean water exposure.

Skin is the body's first line of defense against invading microorganisms. The skin microbiome has been shown to provide immunity against exogenous bacterial colonization. Recreational water exposures may alter the skin microbiome and potentially induce skin infections. This study explored the link between ocean water exposures and the human skin microbiome. Skin microbiome samples were collected, using swabs, from human participants' calves before and after they swam in the ocean, and at 6 hour and 24 hour post-swim. Genomic analysis showed that skin microbiomes were different among individuals before swimming. But after swimming, microbial communities were no longer different, which was demonstrated by a decrease in inter-sample diversity. Taxonomic analysis showed that ocean bacteria, including potential pathogens, replaced the native skin bacteria and remained on the skin for at least 24 hour post-swim. This research provides insight into the relationship between the human skin microbiome and the environment.