[Mechanisms of the therapeutic effect of hyperbaric oxygenation in minor differential pressure in stroke]. / O mekhanizme lechebnogo deistviia giperbaricheskoi oksigenatsii pri malom izbytochnom davlenii pri mozgovom insul'te.

Analysis is made of a complex of clinicoelectrophysiologic, biochemical and biophysical studies conducted in 220 patients with brain stroke, receiving a course of hyperbaric oxygenation (HBO) at minor differential pressure (1.2-1.3 absolute atmospheres). It is shown that HBO can be applied as pathogenetic therapy in patients afflicted with brain stroke. It produces a marked clinical effect and normalizes EEG, REG and acid-alkaline balance, brings about a decrease of initially high lipid peroxidation (LPO), activating antioxidative processes and superoxide dismutase. However, such an effect is only produced by the first HBO sessions at minor differential pressure, which is likely to be due to the substitution action of hyperoxia and activation of antioxidative processes. The studies thus made validate the efficacy of short-term sessions of HBO in patients with brain stroke and the possibility of hyperoxia over-dosage in patients with disturbed antioxidant defence.

[Diagnosis and treatment and preventive measures in the presence of initial manifestations of insufficient cerebral blood supply]. / Diagnostika i lechebno-profilakticheskie meropriiatiia pri nachal'nykh proiavleniiakh nedostatochnosti krovosnabzheniia mozga.

Electrophysiological, ultrasound, biochemical, and psychological studies in 222 patients with initial manifestations of brain blood supply insufficiency (IMBBSI) are presented. A scheme for diagnostic, treatment and dispensary system is offered, principles of IMBBSI therapy are given into account. IMBBSI differentiated treatment leads to steady disappearance of its clinical manifestations in 28.3% of patients and to significant improvement in 58,1% (the last group of patients needs supporting therapy).

[Increased predisposition to syncope in vasovagal syncope]. / O povyshennoi obmorochnoi gotovnosti pri vazovagal'nom obmoroke.

For revealing body peculiarities causing a heightened predisposition to vasovagal syncopes the somatic and neurological status, the general and cerebral hemodynamics, the person's psychological peculiarities, the brain bioelectric activity, changes in catecholamine metabolism, and in adrenocortical function were examined in 131 patients. As a result, factors determining the heightened predisposition to vasovagal syncopes were revealed, and a scheme was drawn which illustrated the development of a vasovagal syncope and the participation of the above factors in the pathogenetic mechanisms of the syncope at its different stages.