RESUMO
It was examined 206 patients with varicocele and infertility in infertile men aged from 25 to 45 years. Stightly best results were obtained after microsurgical operation. Surgical removal of a varicocele as a stage of infertility treatment should not be done as long as interviewed with sterile pair about absence warranty the success of this method of treatment.
Assuntos
Fertilidade , Infertilidade Masculina/cirurgia , Varicocele/cirurgia , Adulto , Humanos , Infertilidade Masculina/complicações , Infertilidade Masculina/diagnóstico , Laparoscopia , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento , Procedimentos Cirúrgicos Urológicos Masculinos , Varicocele/complicações , Varicocele/diagnósticoRESUMO
For the purpose of definition of characteristic morphological changes of testicular tissue which to be surveyed as precancerous, the peritumoral tissue at 40 patients with testicular germ cell tumors (TGCT) which has been spent orchiectomy is investigated and the diagnosis according to classification TNM is established. In peritumoral tissue in 95% patients with testicular germ cell tumors disturbance of spermatogenesis, characteristic for the secretory form of male infertility, are taped. Occurrence of atypical germ cells (TIN) in semen tubules, which were defined in 60% of cases, and overexpressed hyperplasia of Leydig cells of interstition, defined in 82.5% of cases--the typical changes of peritumoral testicular tissue which can be characterised as precancerous changes. Patients with the secretory form of male infertility whith atypical germ cells (TIN) in semen tubules and the overexpressed hyperplasia of Leydig cells, make hight risk group of development of testicular cancer and demand a dispensary observation.
Assuntos
Neoplasias Embrionárias de Células Germinativas/cirurgia , Lesões Pré-Cancerosas/cirurgia , Neoplasias Testiculares/cirurgia , Testículo/patologia , Testículo/cirurgia , Adolescente , Adulto , Transformação Celular Neoplásica , Humanos , Células Intersticiais do Testículo/patologia , Masculino , Pessoa de Meia-Idade , Neoplasias Embrionárias de Células Germinativas/patologia , Orquiectomia , Lesões Pré-Cancerosas/patologia , Túbulos Seminíferos/patologia , Espermatogênese , Neoplasias Testiculares/patologia , Adulto JovemRESUMO
It has been shown that in patients with acute pyelonephritis a spontaneous production of the interleukin IL-1 remains unchanged, while that stimulated with the aid of LPS is significantly below the norm. A spontaneous secretion of IL-2 in patients with chronic pyelonephritis has also been found unchanged, whereas in acute pyelonephritis this same parameter tends to rise above the level recordable in healthy donors. The production of this lymphokine stimulated with the aid of PhHA is significantly lower both in acute and chronic pyelonephritis. The level of cells carrying receptors to IL-2 is appreciably above the norm in patients with acute pyelonephritis, whereas in those presenting with the chronic process this parameter does not differ from that in the control group. The data obtained suggest distinctive features in the interleukin link of immunity (IL-1, IL-1, IL-2P) in patients with pyelonephritis.
