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1.
Georgian Med News ; (224): 82-4, 2013 Nov.
Artigo em Russo | MEDLINE | ID: mdl-24323971

RESUMO

Using high-performance liquid chromatography methods are qualitatively and quantitatively identified most biological important high fatty acids, contained in Ruta graveolens seed oil grown on the experimental plot of Kutateladze Institute of Pharmakochemistry (Georgia) and compare its biological activity. Their relative concentration is expressed as percentages of the total fatty acid component. The sample contained the range of fatty acids from С12:0 to С22:0. The investigation showed different sensitivity of components. In order of elution the list of compound are reported. The oil contained 2,08±0,1 mg% lauric, 2,18±0,1 mg% miristic, 3,98±0,1 mg% palmitic, 30,90±1,2 mg% stearic, 41,92±1,8 mg% oleic, 10,14±0,4 mg% linolic, 6,50±0,3 mg% linolenic, 2,00±0,1 mg% arachinic and 2,10±0,1 mg% begenic acid. The chromatography signals with retention values 7,96 and 14,08 minuts are qualitatively not identified.


Assuntos
Ácidos Graxos/química , Óleos de Plantas/química , Ruta/química , Cromatografia Líquida de Alta Pressão , Ácidos Graxos/classificação , Ácidos Graxos/isolamento & purificação , Humanos , Sementes/química
2.
Georgian Med News ; (218): 82-5, 2013 May.
Artigo em Russo | MEDLINE | ID: mdl-23787514

RESUMO

Using high-performance liquid chromatography methods (Cromatograph PTC-1, repractometer R-401, column Bondopaс C18) were quantitatively and qualitatively identified most biological important high fatty acids, contained in peach oil (Persica Vulgaris) from ost region of Georgia (Kacheti). Their relative concentrations are expressed as percentages of the total fatty acids components. The chromatography investigation shaved, that the oil contained 12,98±1,0mg% linoleic, 9,97±0,3 mg% palmitic, 4,82±0,2 mg% linolenic, 3,58±0,1 mg% begenic and 2,16±0,1 mg% arachinic acids. The predominant fatty acids of peach oil were linoleic, palmitic and oleinic acids. The investigation showed different sensitivity of components contained in peach oil.


Assuntos
Ácidos Graxos/química , Ácidos Graxos/isolamento & purificação , Óleos de Plantas/química , Prunus/química , Ácidos Graxos/classificação , Ácido Linoleico/química , Ácidos Oleicos/química , Ácido Palmítico/química , Óleos de Plantas/administração & dosagem , Óleos de Plantas/isolamento & purificação
3.
Georgian Med News ; (195): 85-7, 2011 Jun.
Artigo em Russo | MEDLINE | ID: mdl-21778549

RESUMO

In this paper, using high-performance liquid chromatography methods were quantitatively and qualitatively identified most biological important high fatty acids, contained in Rkatsiteli grape seed oil of 2010 years crop in Signakhi region of Georgia. The chromatography investigation showed, that the grape seed oil contained 61% linolic acid, 19% oleic, 8% palmitic, 4.5% stearic, 1.4% linolenic and 0.6% arachidonuic acids. In standard diet grape seed oil was added as a food additive (5.0 gr and 10.0 gr on 1.0 kg food). After 15 days fatty acids are carried out from mouse liver (120 inbred mouse), fractioned and using high-performance liquid chromatography the retention values of individual fatty asids are identiced. The investigation showed different sensitivity of components contained in grape seed oil.


Assuntos
Ácidos Graxos Insaturados/análise , Ácidos Graxos Insaturados/farmacologia , Aditivos Alimentares/química , Aditivos Alimentares/farmacologia , Extrato de Sementes de Uva/química , Óleos de Plantas/química , Animais , Membrana Celular/efeitos dos fármacos , Cromatografia Líquida de Alta Pressão , Glicerofosfolipídeos/análise , Glicerofosfolipídeos/farmacologia , Humanos , Ácido Linoleico/análise , Ácido Linoleico/farmacologia , Fígado/efeitos dos fármacos , Camundongos , Ácido Oleico/análise , Ácido Oleico/farmacologia , Triglicerídeos/análise , Triglicerídeos/farmacologia
4.
Georgian Med News ; (191): 73-6, 2011 Feb.
Artigo em Russo | MEDLINE | ID: mdl-21436484

RESUMO

In this paper high fatty acids in the Rkatsiteli grape seed oil were qualitatively and quantitatively identified. In the Rkatsiteli grape seed oil linolenic, oleic, palmitic, stearic, palmitooleinovaya, linoleic and arachidonic acids were identified. The impact of Rkatsiteli grape seed oil as a dietary supplement on the contents of fatty acid synthase and lipids in the livers of mice were determined. Investigations were carried out on 120 inbred mice: for 15 days to a standard diet grape seed oil was added as a food additive. The investigation showed that the optimal use of food additives in the form of oil from Rkatsiteli grape seed plays an important role in maintaining the physiological needs of the human organism.


Assuntos
Suplementos Nutricionais , Ácidos Graxos/análise , Ácidos Graxos/farmacologia , Metabolismo dos Lipídeos/efeitos dos fármacos , Óleos de Plantas/química , Animais , Camundongos , Ratos
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