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Transplant Proc ; 42(2): 547-51, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20304189

RESUMO

UNLABELLED: To evaluate the risk factors for pancreas graft loss within 3 months postoperatively among 170 simultaneous pancreas-kidney transplantation (SPKT) we examined 38 variables. METHODS: Twenty-two variables were related to recipients; 12 to donors and 4 to the surgical procedure. In addition the latest follow-up dates as well as the transplant and/or death dates. Independent variables were examined with reference to the dependent pancreatic loss variable, excluding losses owing to deaths. Variables with statistical significance were analyzed to predict early graft loss. RESULTS: Univariate analyses determined the following significant variables: kidney cold ischemia time, older donors, non-white donors, death cause related to vascular disease, wound infection, and length of extended hospitalization. However, multivariate analysis showed that only donor age and kidney cold ischemia time were significant predictors for early pancreatic graft loss. CONCLUSION: Donor age and kidney cold ischemia time were independently related to pancreatic loss after SPKT within 3 months posttransplantation.


Assuntos
Transplante de Rim/fisiologia , Transplante de Pâncreas/efeitos adversos , Adolescente , Adulto , Fatores Etários , Amilases/metabolismo , Análise de Variância , Índice de Massa Corporal , Causas de Morte , Creatinina/metabolismo , Diabetes Mellitus Tipo 1/complicações , Diabetes Mellitus Tipo 1/cirurgia , Nefropatias Diabéticas/cirurgia , Etnicidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Estudos Retrospectivos , Fatores de Risco , Sódio/sangue , Infecção da Ferida Cirúrgica/mortalidade , Doadores de Tecidos/estatística & dados numéricos , Resultado do Tratamento , Doenças Vasculares/mortalidade
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