1.
Ultrason Sonochem
; 16(6): 711-7, 2009 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19442560
RESUMO
A mild, efficient, facile and eco-friendly procedure for the synthesis of 2,4-diarylthiazoles from arylthioamides and alpha-bromoacetophenones in 1-n-butyl-3-methylimidazolium tetrafluoroborate as a "green" media under ultrasound irradiation at room temperature is described. It is interesting to mention that only one product was obtained when two different alpha-bromoacetophenones were reacted with 1,3-phenyl dithioamide as the substrate. Work-up is very simple and there is no need to purify the product. A recycling study confirmed that the ionic liquid can be reused multiple times without a significant loss in its activity.