RESUMO
AIM: To study clinical efficiency of 12-month administration of berodual in chronic obstructive bronchitis (COB). MATERIALS AND METHODS: The trial entered 33 patients with at least 2-year history of COB and forced expiratory volume per 1 sec (FEV1) not less than 45% of normal value. RESULTS: The best response of clinical parameters and external respiration was observed throughout 3 weeks of berodual inhalations. Dyspnea and cough were cured by the end of the treatment in 40 and 26% of the patients, respectively. Exercise tolerance has improved, FEV1 has increased for the year from 71.9 to 79.1%. CONCLUSION: Long-term berodual monotherapy is able to inhibit progression of bronchial obstruction and symptoms of COB.
Assuntos
Bronquite/tratamento farmacológico , Broncodilatadores/administração & dosagem , Fenoterol/administração & dosagem , Ipratrópio/administração & dosagem , Adulto , Idoso , Bronquite/fisiopatologia , Doença Crônica , Combinação de Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes de Função Respiratória , Fatores de TempoAssuntos
Broncodilatadores/administração & dosagem , Cromolina Sódica/administração & dosagem , Fenoterol/administração & dosagem , Hipersensibilidade Respiratória/tratamento farmacológico , Adulto , Aerossóis , Asma/sangue , Asma/tratamento farmacológico , Asma/fisiopatologia , Combinação de Medicamentos , Feminino , Volume Expiratório Forçado/efeitos dos fármacos , Humanos , Masculino , Pessoa de Meia-Idade , Síndrome Pré-Menstrual/sangue , Síndrome Pré-Menstrual/fisiopatologia , Inibidores de Proteases/sangue , Hipersensibilidade Respiratória/sangue , Hipersensibilidade Respiratória/fisiopatologiaRESUMO
18-45-year-old patients with atopic bronchial asthma free of associated inflammatory diseases received ditek, lomudal and berotek (28, 10 and 10 patients, respectively). Biochemical assessment of allergic inflammation activity demonstrated that ditek is most effective of the above three drugs both in relation to induction of clinical remission and to inhibition of allergic inflammation.