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1.
Heliyon ; 9(12): e22544, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38076174

RESUMO

Road traffic accident (RTA) is a critical global public health concern, particularly in developing countries. Analyzing past fatalities and predicting future trends is vital for the development of road safety policies and regulations. The main objective of this study is to assess the effectiveness of univariate Seasonal Autoregressive Integrated Moving Average (SARIMA) and Facebook (FB) Prophet models, with potential change points, in handling time-series road accident data involving seasonal patterns in contrast to other statistical methods employed by key governmental agencies such as Ghana's Motor Transport and Traffic Unit (MTTU). The aforementioned models underwent training with monthly RTA data spanning from 2013 to 2018. Their predictive accuracies were then evaluated using the test set, comprising monthly RTA data from 2019. The study employed the Box-Jenkins method on the training set, yielding the development of various tentative time series models to effectively capture the patterns in the monthly RTA data. SARIMA(0,1,1)×(1,0,0)12 was found to be the suitable model for forecasting RTAs with a log-likelihood value of -266.28, AIC value of 538.56, AICc value of 538.92, BIC value of 545.35. The findings disclosed that the SARIMA(0,1,1)×(1,0,0)12 model developed outperforms FB-Prophet with a forecast accuracy of 93.1025% as clearly depicted by the model's MAPE of 6.8975% and a Theil U1 statistic of 0.0376 compared to the FB-Prophet model's respective forecasted accuracy and Theil U1 statistic of 84.3569% and 0.1071. A Ljung-Box test on the residuals of the estimated SARIMA(0,1,1)×(1,0,0)12 model revealed that they are independent and free from auto/serial correlation. A Box-Pierce test for larger lags also revealed that the proposed model is adequate for forecasting. Due to the high forecast accuracy of the proposed SARIMA model, the study recommends the use of the proposed SARIMA model in the analysis of road traffic accidents in Ghana.

2.
Heliyon ; 9(8): e18276, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37576298

RESUMO

Many allegations have been levelled against the electoral process of many countries across the world by most opposition leaders, especially when they lose a presidential election e.g. Ghana in 2012 and 2020. Therefore, the need to apply election forensic techniques to the certified election results data of valid votes count to statistically verify if some suspected or possible anomalies and irregularities exist in the voting pattern. This paper seeks to provide a comprehensive review of election forensics techniques and make a comparative analysis of Benford's Second-order test of conformity (using the first two digits) and Hartigans' dip test of unimodality to examine the existence of possible anomalies and irregularities in the 2012 and 2020 presidential elections held in Ghana. The findings of the two tests suggest that the electoral process produced possible anomalous data in the 2012 presidential election results (with an overall 16.67% suspected anomalies), whilst possible non-anomalous data was produced in the 2020 presidential election results (with an overall 0% suspected anomaly) of valid votes count. Therefore, the study recommends that for better statistical data analysis on election anomaly detection, Benford's test of conformity and Hartigans' dip test of unimodality should serve as baseline tests (initial screening tools), highlighting areas that may require further investigation or more rigorous analysis and progressively dig deeper into the application of finite mixture fraud models and machine learning techniques. In spite of the promising results Benford's Law, dip test, machine learning algorithms, and network analysis have produced in detecting irregularities in election data, real-world applications remain challenging, particularly when dealing with complex and evolving forms of fraud. Therefore, there is the need for continuous research and innovation to improve the accuracy and effectiveness of these methods and promote transparency and accountability in democratic societies.

3.
Interdiscip Perspect Infect Dis ; 2019: 9362492, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31827507

RESUMO

Several mathematical and standard epidemiological models have been proposed in studying infectious disease dynamics. These models help to understand the spread of disease infections. However, most of these models are not able to estimate other relevant disease metrics such as probability of first infection and recovery as well as the expected time to infection and recovery for both susceptible and infected individuals. That is, most of the standard epidemiological models used in estimating transition probabilities (TPs) are not able to generalize the transition estimates of disease outcomes at discrete time steps for future predictions. This paper seeks to address the aforementioned problems through a discrete-time Markov chain model. Secondary datasets from cohort studies were collected on HIV, tuberculosis (TB), and hepatitis B (HB) cases from a regional hospital in Ghana. The Markov chain model revealed that hepatitis B was more infectious over time than tuberculosis and HIV even though the probability of first infection of these diseases was relatively low within the study population. However, individuals infected with HIV had comparatively lower life expectancies than those infected with tuberculosis and hepatitis B. Discrete-time Markov chain technique is recommended as viable for modeling disease dynamics in Ghana.

4.
Can J Infect Dis Med Microbiol ; 2019: 2697618, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31933708

RESUMO

Most mortality studies usually attribute death to single disease, while various other diseases could also act in the same individual or a population at large. Few works have been done by considering HIV, Tuberculosis (TB), and Hepatitis B (HB) as jointly acting in a population in spite of their high rate of infections in Ghana. This study applied competing risk methods on these three diseases by assuming they were the major risks in the study population. Among all opportunistic infections that could also act within HIV-infected individuals, TB has been asserted to be the most predominant. Other studies have also shown cases of HIV and Hepatitis B coinfections. The validity of these comorbidity assertions was statistically determined by exploring the conditional dependencies existing among HIV, TB, and HB through Bayesian networks or directed graphical model. Through Classification tree, sex and age group of individuals were found as significant demographic predictors that influence the prevalence of HIV and TB. Females were more likely to contract HIV, whereas males were prone to contracting TB.

5.
Springerplus ; 5(1): 1196, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27516934

RESUMO

The main objective of the study is to compare the Newton-Cotes methods such as the Trapezium rule, Simpson 1/3 rule and Simpson 3/8 rule to estimate the area under the Lorenz curve and Gini coefficient of income using polynomial function with degree 5. Comparing the Gini coefficients of income computed from the Polynomial function with degree 5 for the Trapezium, Simpson 1/3 and Simpson 3/8 methods using the relative errors showed that the trapezium rule, Simpson's 1/3 rule and Simpson's 3/8 rule show negative biases with the Simpson 1/3 rule yielding the lowest absolute relative true error of 4.230711 %.

6.
Springerplus ; 5(1): 1315, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27547689

RESUMO

[This corrects the article DOI: 10.1186/s40064-016-2868-z.].

7.
Springerplus ; 4: 696, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26587364

RESUMO

Modelling of extreme events has always been of interest in fields such as hydrology and meteorology. However, after the recent global financial crises, appropriate models for modelling of such rare events leading to these crises have become quite essential in the finance and risk management fields. This paper models the extreme values of the Ghana stock exchange all-shares index (2000-2010) by applying the extreme value theory (EVT) to fit a model to the tails of the daily stock returns data. A conditional approach of the EVT was preferred and hence an ARMA-GARCH model was fitted to the data to correct for the effects of autocorrelation and conditional heteroscedastic terms present in the returns series, before the EVT method was applied. The Peak Over Threshold approach of the EVT, which fits a Generalized Pareto Distribution (GPD) model to excesses above a certain selected threshold, was employed. Maximum likelihood estimates of the model parameters were obtained and the model's goodness of fit was assessed graphically using Q-Q, P-P and density plots. The findings indicate that the GPD provides an adequate fit to the data of excesses. The size of the extreme daily Ghanaian stock market movements were then computed using the value at risk and expected shortfall risk measures at some high quantiles, based on the fitted GPD model.

8.
Springerplus ; 4: 525, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26435890

RESUMO

Although, there exists numerous literature on the procedure for forecasting or predicting election results, in Ghana only opinion poll strategies have been used. To fill this gap, the paper develops Markov chain models for forecasting the 2016 presidential election results at the Regional, Zonal (i.e. Savannah, Coastal and Forest) and the National levels using past presidential election results of Ghana. The methodology develops a model for prediction of the 2016 presidential election results in Ghana using the Markov chains Monte Carlo (MCMC) methodology with bootstrap estimates. The results were that the ruling NDC may marginally win the 2016 Presidential Elections but would not obtain the more than 50 % votes to be declared an outright winner. This means that there is going to be a run-off election between the two giant political parties: the ruling NDC and the major opposition party, NPP. The prediction for the 2016 Presidential run-off election between the NDC and the NPP was rather in favour of the major opposition party, the NPP with a little over the 50 % votes obtained.

9.
Springerplus ; 4: 329, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26180749

RESUMO

This research article aimed at modeling the variations in the dollar/cedi exchange rate. It examines the applicability of a range of ARCH/GARCH specifications for modeling volatility of the series. The variants considered include the ARMA, GARCH, IGARCH, EGARCH and M-GARCH specifications. The results show that the series was non stationary which resulted from the presence of a unit root in it. The ARMA (1, 1) was found to be the most suitable model for the conditional mean. From the Box-Ljung test statistics x-squared of 1476.338 with p value 0.00217 for squared returns and 16.918 with 0.0153 p values for squared residuals, the null hypothesis of no ARCH effect was rejected at 5% significance level indicating the presence of an ARCH effect in the series. ARMA (1, 1) + GARCH (1, 1) which has all parameters significant was found to be the most suitable model for the conditional mean with conditional variance, thus showing adequacy in describing the conditional mean with variance of the return series at 5% significant level. A 24 months forecast for the mean actual exchange rates and mean returns from January, 2013 to December, 2014 made also showed that the fitted model is appropriate for the data and a depreciating trend of the cedi against the dollar for forecasted period respectively.

10.
Toxicol Mech Methods ; 20(2): 96-104, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20100038

RESUMO

Excess hepatic iron generates reactive oxygen species that result in oxidative stress and oxidative damage to the liver. Vitamins have hitherto been considered to be a possible remedy. The aim of this study was to determine if high doses of delta-alpha-tocopherol supplementation in iron overload would ameliorate the oxidative stress. Four groups of 20 male Wistar albino rats were studied: group 1 (control) was fed normal diet, group 2 (Fe) 0.75% Ferrocene iron, group 3 (FV gp) 0.75% Ferrocene/delta-alpha-tocopherol (10x RDA), group 4 (V gp) normal diet/delta-alpha-tocopherol. After 12 months, serum iron, reduced glutathione, catalase, vitamin C, Oxygen Radical Absorbance Capacity, lipid peroxidation, 8-hydroxy-2'-deoxyguanosine (8-OHdG), aspartate transaminase (AST), and alanine transaminase (ALT) were measured. Vitamin C levels were: F gp = 5.04 +/- 0.09; FV gp = 5.85 +/- 0.13 (micromol/l) (p < 0.05). 8-hydroxy-2'-deoxyguanosine levels were: F gp = 143.6 +/- 6.4; FV gp = 179.2 +/- 18.2 (ng/ml) (p < 0.05). Oxidative liver damage, as determined by serum AST and ALT levels, was not attenuated by alpha-tocopherol. A positive correlation existed between vitamin C and 8-OHdG, suggesting possible delta-alpha-tocopherol toxicity.


Assuntos
Antioxidantes/toxicidade , Ácido Ascórbico/metabolismo , Desoxiguanosina/análogos & derivados , Sobrecarga de Ferro/induzido quimicamente , Fígado/efeitos dos fármacos , Estresse Oxidativo/efeitos dos fármacos , Vitaminas/toxicidade , alfa-Tocoferol/toxicidade , 8-Hidroxi-2'-Desoxiguanosina , Administração Oral , Alanina Transaminase/sangue , Animais , Antioxidantes/administração & dosagem , Ácido Ascórbico/sangue , Aspartato Aminotransferases/sangue , Biomarcadores/sangue , Catalase/sangue , Desoxiguanosina/metabolismo , Modelos Animais de Doenças , Compostos Ferrosos , Glutationa/sangue , Ferro/sangue , Sobrecarga de Ferro/metabolismo , Sobrecarga de Ferro/patologia , Peroxidação de Lipídeos/efeitos dos fármacos , Fígado/metabolismo , Fígado/patologia , Masculino , Metalocenos , Ratos , Ratos Wistar , Fatores de Tempo , Regulação para Cima , Vitaminas/administração & dosagem , alfa-Tocoferol/administração & dosagem
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