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BMJ Case Rep ; 13(6)2020 Jun 11.
Artigo em Inglês | MEDLINE | ID: mdl-32532902

RESUMO

A man in his 80s presented to the hospital with a 36-hour history of fever, myalgia, bilateral shoulder and right knee pain. Joint fluid aspirates from his shoulders and right knee isolated Gram-negative diplococci. After failing to grow on standard and selective media, Neisseria meningitidis was identified by 16s PCR and subsequently typed as serogroup C. He had no clinical features of meningitis or meningococcaemia. Blood cultures were negative and an EDTA blood sample was negative for meningococcal ctrA gene. Urine PCR was negative for Neisseria gonorrhoeae He was treated successfully with two arthroscopic joint washouts of his right knee, aspirates of both shoulders, 40 days of intravenous ceftriaxone and intensive physiotherapy as both an inpatient and outpatient. In the literature, we have not found any previously documented cases of serogroup C meningococcus causing polyarticular primary septic arthritis in this age group or guidance on duration of antibiotic treatment. Literature on the impact of rehabilitation to baseline function was also found to be lacking. Although rare, primary meningococcal arthritis (PMA) should be considered as a differential diagnosis in cases of acute polyarticular septic arthritis. Polyarticular PMA in older adults may require prolonged rehabilitation before one might expect to return to premorbid function.


Assuntos
Artrite Infecciosa , Artroscopia/métodos , Ceftriaxona/administração & dosagem , Articulação do Joelho , Infecções Meningocócicas , Neisseria meningitidis Sorogrupo C/isolamento & purificação , Articulação do Ombro , Administração Intravenosa , Idoso de 80 Anos ou mais , Antibacterianos/administração & dosagem , Artrite Infecciosa/diagnóstico , Artrite Infecciosa/microbiologia , Artrite Infecciosa/reabilitação , Artrite Infecciosa/terapia , Diagnóstico Diferencial , Humanos , Articulação do Joelho/microbiologia , Articulação do Joelho/fisiopatologia , Masculino , Infecções Meningocócicas/diagnóstico , Infecções Meningocócicas/fisiopatologia , Infecções Meningocócicas/terapia , Modalidades de Fisioterapia , Reabilitação/métodos , Articulação do Ombro/microbiologia , Articulação do Ombro/fisiopatologia , Irrigação Terapêutica/métodos , Resultado do Tratamento
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