Relations between protective traits and psychological distress among women experiencing infertility.

The aim of this study was to examine the association between traits associated with adaptive self-management and psychological distress in women experiencing infertility. A sample of 326 women reported on their infertility experience; their tendencies with respect to self-compassion, emotion regulation, and positivity; and their current psychological distress. Results showed negative associations of self-compassion and positive orientation with depression in the past month. The additional distress experienced by women with primary infertility was attenuated by self-compassion and the tendency to not suppress emotional expression. Traits that enable effective self-management buffer the effects of infertility on psychology health.

Patch/plaque mycosis-fungoides-like presentations of DUSP22-translocated T-cell lymphomas.

The DUSP22-IRF4 gene rearrangement results in downregulation of DUSP22, a presumed tumor suppressor in T-cell lymphomagenesis. It has been described in some cases of primary cutaneous and systemic anaplastic large-cell lymphoma, lymphomatoid papulosis, and transformed mycosis fungoides. Here we describe two patients with clinical lesions resembling patch/plaque mycosis fungoides that did not meet WHO criteria for large-cell transformation on histopathology yet showed a DUSP22 translocation. One patient who had a history of systemic anaplastic large-cell lymphoma with DUSP22 translocation presented with cutaneous involvement by his systemic lymphoma along with lymphomatoid papulosis and mycosis-fungoides-like lesions, all showing an identical immunophenotype and T-cell clone. These cases expand the spectrum of DUSP22-rearranged lymphomas to include mycosis-fungoides-like presentations without large-cell transformation.