RESUMO
To clarify the epidemiologic and clinical features of community-acquired influenza C infection in children, we took specimens throughout the year from a larger number of patients with acute respiratory illnesses in a pediatric clinic in Yamagata, Japan. During a 2-year survey, 20 strains of influenza C virus were isolated from 13,426 specimens. These isolates were recovered throughout the year. The ages of patients with influenza C virus isolates ranged from 2 months to 11 years and peaked at the age of 1 year. The clinical diagnosis of patients with influenza C virus infection included bronchitis in one child and pneumonia in four. Community-acquired influenza C infection in children can cause a variety of respiratory illnesses that cannot be clinically differentiated from those caused by other viruses.
Assuntos
Gammainfluenzavirus , Influenza Humana/epidemiologia , Infecções Respiratórias/epidemiologia , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Influenza Humana/complicações , Influenza Humana/microbiologia , Gammainfluenzavirus/isolamento & purificação , Japão/epidemiologia , Masculino , Infecções Respiratórias/microbiologia , Estações do AnoRESUMO
Detection of rotavirus by electron microscopy was conducted with fecal specimens from 1,722 infants and young children with acute diarrhea, during a 41-month survey from April 1978 through December 1981 in Guayaquil, Ecuador; 376 of these specimens (21.8%) were positive. The detection rate was higher during the dry season (May to November; 25.2%) than during the rainy season (December to April; 14.7%). When rotaviruses isolated from 59 patients hospitalized with diarrhea (from April 1979 to July 1981) were subjected to genome RNA analysis by polyacrylamide gel electrophoresis, a single dominant electropherotype was found with other less common electropherotypes. An atypical rotavirus with a unique property was also found.
Assuntos
Infecções por Rotavirus/epidemiologia , Infecções por Adenoviridae/epidemiologia , Animais , Pré-Escolar , Equador , Eletroforese em Gel de Poliacrilamida , Fezes/microbiologia , Gastroenterite/microbiologia , Humanos , Lactente , Microscopia Eletrônica , RNA Viral/isolamento & purificação , Rotavirus , Infecções por Rotavirus/microbiologia , Estações do AnoRESUMO
One strain of atypical rotavirus, morphologically indistinguishable from known rotaviruses but lacking the common group antigen of typical rotavirus detectable by an enzyme-linked immunosorbent assay (ELISA), was isolated from one of 152 Ecuadorian infants with acute rotavirus gastroenteritis. The genome analysis by polyacrylamide gel electrophoresis revealed a unique RNA pattern clearly distinct from that of typical rotaviruses.
Assuntos
Diarreia Infantil/microbiologia , Rotavirus/isolamento & purificação , Equador , Feminino , Humanos , Lactente , RNA Viral/análise , Rotavirus/genéticaRESUMO
The sequence of antibody production to various virus-specific antigens in CMV infection in infancy was studied. In healthy infants, IgG EA antibody was demonstrated in 18% of cord sera, and disappeared within two months after birth in all cases not shedding virus. The nonmaternal EA antibody was produced following virus excretion and decreased rapidly following cessation of virus excretion. Thus, demonstration of EA antibody in infants after 2 months of age was found to indicate acquired CMV infection, even when CMV could not be isolated. IgM MA antibody did not persist as long as EA antibody, disappearing before cessation of virus excretion. Both IgG EA and IgM MA antibodies were more frequently demonstrated in infants with hepatitis than in healthy infants. These findings suggest the possible association of CMV with hepatitis in infants.