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1.
NPJ Microgravity ; 10(1): 52, 2024 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-38714711

RESUMO

Sessile water droplet evaporation in varied gravity and electric fields has been experimentally studied. Specifically, the influences of gravity and electric fields are investigated in the context of the heat flux distribution beneath the droplets, as well as the droplet mechanics and resulting shapes. Experimental testing was carried out during a European Space Agency (ESA) Parabolic Flight Campaign (PFC 66). The droplets tested evaporated with a pinned contact line, a single wettability condition, and varied droplet volume and substrate heat flux. The peak heat transfer was located at the contact line for all cases. The peak heat flux, average heat flux, and droplet evaporation rate were shown to vary strongly with gravity, with higher values noted for hypergravity conditions and lower values in microgravity conditions. The droplet thermal inertia was shown to play a significant role, with larger droplets taking more time to reach thermal equilibrium during the parabolic testing period. No significant impact of the electric field on the droplet evaporation was noted for these test conditions.

2.
Anaesth Rep ; 8(2): 131-134, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33210090

RESUMO

A 35-year-old gravida 3, para 0 woman required an emergency caesarean section for pre-eclampsia with severe features including a platelet count of 7 × 109.l-1. The patient's thrombocytopaenia was an acute on chronic presentation. In addition to pre-eclampsia, the patient had a complex background history which included autoimmune lymphoproliferative syndrome, the manifestations of which include autoimmune cytopaenias and recurrent infections. The patient also had common variable immune deficiency and acquired C1-esterase inhibitor deficiency which may cause life-threatening angioedema, including of the airway. In this report, we describe the potential anaesthetic challenges posed by this pre-eclamptic, immunologically compromised patient with severe thrombocytopaenia and the potential for difficult airway, and how these were addressed in a safe and timely manner. Specifically, we highlight the important considerations when performing a general anaesthetic in this unique combination of circumstances. Although the patient's conditions are rare, this case demonstrates that early multidisciplinary team input can help successfully guide the management of medically complex pregnant patients.

3.
Int J Obstet Anesth ; 43: 9-12, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32437913

RESUMO

We report a case of permanent high-frequency hearing loss and tinnitus in a 38-year-old woman following an unrecognised dural puncture during epidural placement. The patient reported subjective unilateral hearing loss and tinnitus, along with a post-dural puncture headache, four hours post-delivery. The patient's headache resolved following two epidural blood patches, however, hearing loss and tinnitus persisted longer than two years. Long-term auditory symptoms following epidural analgesia in labour are very unusual findings.


Assuntos
Analgesia Epidural/efeitos adversos , Analgesia Obstétrica/efeitos adversos , Perda Auditiva/etiologia , Cefaleia Pós-Punção Dural/etiologia , Punção Espinal/efeitos adversos , Zumbido/etiologia , Adulto , Placa de Sangue Epidural/métodos , Espaço Epidural , Feminino , Humanos , Cefaleia Pós-Punção Dural/terapia
4.
Anaesth Rep ; 7(1): 53-56, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-32051949

RESUMO

Premature ventricular contractions are common in the general population and are often seen during general anaesthesia. A high frequency of premature ventricular contractions may be associated with underlying left ventricular dysfunction. Premature ventricular contraction-induced cardiomyopathy is a rare disease and requires cardiologist input into peri-operative management. Medical and interventional management strategies may completely reverse the disease process. A 19-year-old man was scheduled for removal of tibial metalwork, due to chronic pain, and ventricular bigeminy was noted in the anaesthetic room before induction of anaesthesia. Surgery was postponed and he was later diagnosed with premature ventricular contraction-induced cardiomyopathy. Ventricular bigeminy noted before induction of anaesthesia may not always be benign.

5.
Ir Med J ; 111(10): 842, 2018 12 06.
Artigo em Inglês | MEDLINE | ID: mdl-30560637

RESUMO

We describe the case of a 61-year-old immunocompetent male who developed septic shock and multiorgan failure due to Capnocytophaga canimorsus (C. canimorsus) bloodstream infection, sustained from a dog bite. Unusually, this patient developed acute liver failure and splenic infarction in addition to many of the better-known clinical sequelae of C. canimorsus infection.


Assuntos
Mordeduras e Picadas/complicações , Mordeduras e Picadas/microbiologia , Capnocytophaga , Cães/microbiologia , Infecções por Bactérias Gram-Negativas/etiologia , Infecções por Bactérias Gram-Negativas/microbiologia , Insuficiência de Múltiplos Órgãos/etiologia , Choque Séptico/etiologia , Choque Séptico/microbiologia , Animais , Humanos , Imunocompetência , Falência Hepática Aguda/etiologia , Masculino , Pessoa de Meia-Idade , Infarto do Baço/etiologia
6.
Ir J Med Sci ; 187(1): 207-213, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28597250

RESUMO

PURPOSE: The purpose of this study is to introduce peer teaching of communication skills to first-year anaesthesia trainees in Ireland and to evaluate their perception of this teaching modality. METHODS: Seventy-nine first-year anaesthesia trainees participated in a novel peer-led communication skills programme over a 2-year period (Y1, Y2). A Likert scaling questionnaire was developed to explore trainee perception of the peer teaching programme. RESULTS: Of the 79 respondents (36 in Y1 and 43 in Y2), 99% either agreed or strongly agreed that the peer teachers were successful in their role. Ninety-two percent requested formal peer teaching in other areas of training. The trainees regarded a peer teacher as an appropriate information provider (92%), role model (88%), planner (88%) and facilitator (94%), but less so as an assessor (70%). The most consistently stated strength of peer teaching was the relatability of peer teachers with their lack of experience cited as the main weakness. Eighty percent of participants preferred peer teaching to regular expert teaching. CONCLUSION: This study highlights the positive attitudes of first-year anaesthesia trainees towards a novel peer teaching programme in communication skills. This author recommends that peer teaching is further developed within postgraduate medical programmes to maximise learning for trainees in the student and teacher roles and to redistribute the teaching burden within clinical departments.


Assuntos
Anestesiologia/educação , Educação de Graduação em Medicina/métodos , Ensino/tendências , Comunicação , Feminino , Humanos , Masculino , Grupo Associado , Estudantes de Medicina , Inquéritos e Questionários
8.
Plant Dis ; 101(9): 1621-1626, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30677333

RESUMO

Wheat streak mosaic (WSM) caused by Wheat streak mosaic virus, which is transmitted by the wheat curl mite (Aceria tosichella), is a major yield-limiting disease in the Texas High Plains. In addition to its impact on grain production, the disease reduces water-use efficiency by affecting root development. Because of the declining Ogallala Aquifer water level, water conservation has become one of the major pressing issues in the region. Thus, questions are often raised as to whether it is worthwhile to irrigate infected fields in light of the water conservation issues, associated energy costs, and current wheat prices. To address some of these questions, field experiments were conducted in 2013 and 2016 at two separate locations to determine whether grain yield could be predicted from disease severity levels, assessed early in the spring, for potential use as a decision tool for crop management, including irrigation. In both fields, disease severity assessments started in April, using a handheld hyperspectral radiometer with which reflectance measurements were taken weekly in multiple plots in arbitrarily selected locations across the fields. The relationship between WSM severity levels and grain yield for the different assessment dates were determined by fitting reflectance and yield values into the logistic regression function. The model predicted yield levels with r2 values ranging from 0.67 to 0.85 (P < 0.0001), indicating that the impact of WSM on grain yield could be fairly well predicted from early assessments of WSM severity levels. As the disease is normally progressive over time, this type of information will be useful for making management decisions of whether to continue irrigating infected fields, especially if combined with an economic threshold for WSM severity levels.


Assuntos
Doenças das Plantas , Potyviridae , Triticum , Agricultura , Animais , Grão Comestível/virologia , Ácaros/virologia , Doenças das Plantas/prevenção & controle , Doenças das Plantas/virologia , Potyviridae/fisiologia , Texas , Triticum/crescimento & desenvolvimento , Triticum/virologia
9.
10.
Environ Technol ; 29(1): 55-65, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18610545

RESUMO

Solar drying has been used extensively to dewater biosolids for ease of transportation and to a lesser degree to reduce pathogens prior to land application. The nitrogen in biosolids makes them a relatively inexpensive but valuable source of fertilizer. In this study, nitrogen loss from tilled and untilled biosolids was investigated during the solar drying process. Samples of aerobically and anaerobically digested biosolids during three solar drying experiments were analyzed for their nitrate (NO3-) and ammonium (NH4+) ions concentrations. Nitrogen losses varied depending on the solar drying season and tillage. Although not directly measured, the majority of nitrogen loss occurred through ammonia volatilization; organic nitrogen content (organic N) remained relatively stable for each sample, nitrate concentrations for the majority of samples remained below detectable levels and the decline of ammonium-nitrogen (NH4(+)-N) generally followed the trend of moisture loss in the biosolids.


Assuntos
Nitrogênio/análise , Esgotos/análise , Luz Solar , Dessecação/métodos , Eliminação de Resíduos/métodos
11.
Histopathology ; 47(6): 575-81, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16324194

RESUMO

AIMS: To investigate the differentiation pattern of epithelioid sarcoma in terms of perineurial and endothelial differentiation, and its relationship to that of meningioma. METHODS AND RESULTS: Nine cases of epithelioid sarcoma and five cases of meningioma were studied in an immunohistochemical analysis of 'perineurial' antigens [GLUT-1, claudin-1, epithelial membrane antigen (EMA) and VE-cadherin] and of 'endothelial' antigens not present on normal perineurium (CD34, CD31, Fli-1). Both epithelioid sarcoma and meningioma showed frequent expression of the perineurial markers GLUT-1, claudin-1 and EMA. VE-cadherin was identified in one of five meningiomas, and in the only case of epithelioid sarcoma in which suitably fixed material was available. CD34 was expressed by all epithelioid sarcomas studied but by none of the meningiomas. Fli-1 was present in a substantial majority of epithelioid sarcomas and by all the meningiomas. CD31 was not detected in any epithelioid sarcoma or meningioma. CONCLUSIONS: The results were evaluated in the context of previous immunohistochemical, ultrastructural and genetic studies and suggest that epithelioid sarcoma may be a form of malignant perineurioma with a range of differentiation (epithelial features) akin to that seen in meningioma, reflecting the close relationship between perineurium and meningothelium.


Assuntos
Biomarcadores Tumorais/metabolismo , Diferenciação Celular , Nervos Periféricos/metabolismo , Sarcoma/metabolismo , Antígenos CD , Antígenos CD34/metabolismo , Caderinas/metabolismo , Claudina-1 , Transportador de Glucose Tipo 1/metabolismo , Humanos , Imuno-Histoquímica , Proteínas de Membrana/metabolismo , Mucina-1/metabolismo , Neoplasias de Bainha Neural/metabolismo , Neoplasias de Bainha Neural/patologia , Nervos Periféricos/citologia , Proteína Proto-Oncogênica c-fli-1/metabolismo , Sarcoma/patologia , Sensibilidade e Especificidade
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