RESUMO
933 children with rheumatic fever hospitalised in Clinic in the period of 40 years (from 1995 to the end of 1994) were analysed in order to establish the fluctuation of patients number and changes in clinical appearance. Patients were divided in 4 groups: I. the patients hospitalised from 1955-1964 (472 patients), II. from 1965-1974 (307), III. from 1975-1984 (135), IV. from 1985-1994 (19). The data for Republic Croatia show the steady fall of the number of hospitalised children with rheumatic fever. Carditis with polyarthritis were present in the largest part of our patients (446 namely 47.8%). The number of recurrences fell equally with the number of patients with rheumatic fever. However, ratio between the number of patients with rheumatic fever and the number of recurrences did not change essentially, that was 11-15.85% in the periods considered. The percent of hospitalised children with fixed rheumatic heart disease was 4.23% in the I. period to as much as 15.5% in the III. period from totally hospitalised children with rheumatic fever. In the last time the disease became mild in its development. All children with suspicion on rheumatic fever should be hospitalised. The prophylaxis, primary or secondary, should be carried out intramusculary with benzithine penicillin G, as proved as the best, in order to ensure that the child virtually received the prophylaxis.
Assuntos
Febre Reumática/epidemiologia , Adolescente , Criança , Pré-Escolar , Croácia/epidemiologia , Feminino , Humanos , Lactente , Masculino , Prevalência , Febre Reumática/prevenção & controleRESUMO
The patients were 117 children (aged 4 months to 14 years) with uncomplicated urinary tract infections caused by co-trimoxazole-sensitive Escherichia coli. The patients were randomly assigned to receive treatment with co-trimoxazole for 3 days (n = 58) or 7 days (n = 59). Urine was analyzed for bacteria before and immediately after treatment and again at 1 and 2 months. After 3 days' treatment, infection persisted in 14 of 31 patients with P-fimbriated strains of E coli and in 1 of 27 patients with non-P-fimbriated strains. After 7 days' treatment, infection persisted in 2 of 40 patients with fimbriated strains and in none of the 19 patients with nonfimbriated strains. One or 2 months after treatment, 3 days' treatment was rated successful in 26 of 27 patients with nonfimbriated strains and in none of the patients with fimbriated strains. Seven days' treatment was rated successful in all patients with nonfimbriated strains and in 32 of 40 patients with fimbriated strains. The results indicate that the length of treatment of urinary tract infections in children should be adjusted according to the presence of bacterial P-fimbriae in addition to the patients' clinical condition.
Assuntos
Escherichia coli/isolamento & purificação , Fímbrias Bacterianas/efeitos dos fármacos , Combinação Trimetoprima e Sulfametoxazol/administração & dosagem , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Infecções Urinárias/tratamento farmacológico , Adolescente , Criança , Pré-Escolar , Esquema de Medicação , Escherichia coli/efeitos dos fármacos , Feminino , Humanos , Lactente , Masculino , Valor Preditivo dos Testes , Distribuição Aleatória , Infecções Urinárias/microbiologiaAssuntos
Cálcio/urina , Creatinina/urina , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Fatores de TempoAssuntos
Pediatria/história , Criança , Serviços de Saúde da Criança/história , História do Século XV , História do Século XVI , História do Século XVII , História do Século XVIII , História do Século XIX , História do Século XX , História Medieval , Hospitais Pediátricos/história , Humanos , IugosláviaAssuntos
Hipertensão/epidemiologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Masculino , IugosláviaRESUMO
Leucocyte-mediated phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) were tested in 48 children with type-1 diabetes and in 22 healthy children. Both phagocytosis and ADCC for opsonized 51Cr-erythrocytes significantly decreased in the diabetics. Phagocytosis decreased in well and in poorly balanced diabetics, but the latter, having type-1 diabetes for less than 5 years, exhibited a lower phagocytic capacity than the patients with a longer duration of disease. The decrease of ADCC in poorly balanced patients was greater than in the well balanced ones as compared to the controls. The duration of diabetes was without influence on their leucocytes' ADCC.
Assuntos
Citotoxicidade Celular Dependente de Anticorpos , Fagocitose , Adolescente , Criança , Pré-Escolar , Diabetes Mellitus , Feminino , Humanos , Leucócitos/metabolismo , MasculinoRESUMO
The authors report a case of acute pancreatitis and cholelithiasis in a 13-year-old boy. During the clinical course of the disease temporary cholestatic jaundice appeared with pleural effusion and with biochemical relapse after the beginning of oral nutrition. The diagnosis of acute pancreatitis and associated gallstone was established by clinical and laboratory findings. The authors emphasize the diagnostic importance of the plain abdominal film and of elevated renal amylase clearance. As the etiologic diagnosis was clear, cholecystectomy was postponed until the laboratory findings proved the recovery of the patient.
