RESUMO
Antagonistic activity of 74 cultures of lactic acid bacteria, isolated from healthy and osteoporotic women-patients aged 50-79 years, has been studied. It has been shown that the inhibitory effect of the strain studied was independent of the health of women (control group of women or patients with osteoporosis), but had strain specificity. Seventeen most active strains of lactobacilli, which showed the highest inhibitory activity against B. cereus, P. aeruginosa, P. vulgaris were selected. Only 6 strains of lactobacillus demonstrated specific antagonistic activity against the test-strains.
Assuntos
Antibiose , Bacillus cereus/efeitos dos fármacos , Ácido Láctico/metabolismo , Lactobacillaceae/fisiologia , Osteoporose/microbiologia , Proteus vulgaris/efeitos dos fármacos , Pseudomonas aeruginosa/efeitos dos fármacos , Idoso , Bacillus cereus/crescimento & desenvolvimento , Meios de Cultura , Feminino , Humanos , Ácido Láctico/farmacologia , Lactobacillaceae/isolamento & purificação , Viabilidade Microbiana/efeitos dos fármacos , Pessoa de Meia-Idade , Proteus vulgaris/crescimento & desenvolvimento , Pseudomonas aeruginosa/crescimento & desenvolvimento , Especificidade da EspécieRESUMO
The strains of lactic acid bacteria have been isolated from the intestine of older women. These strains were identified and their biological activity was studied. It has been established that Lactobacillus acidophilus, L. plantarum, L. salivarius var. salivarius and Enterococcus faecium had the highest antagonistic activity against opportunistic microorganisms. It has been revealed, that the adhesive properties and antibiotic resistance of the tested cultures had strain specificity. Most of the isolates were highly adhesive and did not produce hemolysins.