1.
J Am Chem Soc
; 130(19): 6281-7, 2008 May 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18412344
RESUMO
The first total synthesis of roquefortine C is achieved by implementation of a novel elimination strategy to construct the thermodynamically unstable E-dehydrohistidine moiety. Molecular modeling studies are presented which explain the instability of the roquefortine C structure compared to that of isoroquefortine C.