Hidradenitis suppurativa: epidemiological study of cases diagnosed at a dermatological reference center in the city of Bauru, in the Brazilian southeast State of São Paulo, between 2005 and 2015.

BACKGROUND:: Hidradenitis is a chronic inflammatory disease of the hair follicles. A treatment is necessary due to chronicity and psychological changes that patient present. OBJECTIVE:: To investigate epidemiological aspects and elaborate a risk group profile, promote early diagnosis and contribute to the knowledge about the disease. METHODS:: This cross-sectional descriptive study with retrospective analysis of medical records of 194 patients diagnosed with hidrosadenitis in a dermatological reference center in the city of Bauru (SP) between 2005 and 2015. RESULTS:: Females accounted for 74% of cases. The age at diagnosis ranged from 10 to 67 years and the majority was within the 3rd and 4th decade of life. It occurred Association with diabetes mellitus in 33%, obesity in 55% and smoking in 61% was observed. Mean time between the onset of the disease and diagnosis was nine years. Hurley stage II was the most common at diagnosis. The therapeutic option mostly used in Hurley I and II was systemic antibiotics and in Hurley III was surgery. STUDY LIMITATIONS:: the main limitation of this study is its retrospective design, which does not allow the true clinical confirmation of the disease by investigators. CONCLUSION:: we outlined the following profile: women, caucasian, between 3rd and 4th decade of life, associated with obesity, smoking, late diagnosis and multiple potential therapeutic modalities. We highlight the importance of studies like this in order to identify risk groups and encourage early diagnosis.

Hidradenitis suppurativa: epidemiological study of cases diagnosed at a dermatological reference center in the city of Bauru, in the Brazilian southeast State of São Paulo, between 2005 and 2015

Abstract: Background: Hidradenitis is a chronic inflammatory disease of the hair follicles. A treatment is necessary due to chronicity and psychological changes that patient present. Objective: To investigate epidemiological aspects and elaborate a risk group profile, promote early diagnosis and contribute to the knowledge about the disease. Methods: This cross-sectional descriptive study with retrospective analysis of medical records of 194 patients diagnosed with hidrosadenitis in a dermatological reference center in the city of Bauru (SP) between 2005 and 2015. Results: Females accounted for 74% of cases. The age at diagnosis ranged from 10 to 67 years and the majority was within the 3rd and 4th decade of life. It occurred Association with diabetes mellitus in 33%, obesity in 55% and smoking in 61% was observed. Mean time between the onset of the disease and diagnosis was nine years. Hurley stage II was the most common at diagnosis. The therapeutic option mostly used in Hurley I and II was systemic antibiotics and in Hurley III was surgery. Study limitations: the main limitation of this study is its retrospective design, which does not allow the true clinical confirmation of the disease by investigators. Conclusion: we outlined the following profile: women, caucasian, between 3rd and 4th decade of life, associated with obesity, smoking, late diagnosis and multiple potential therapeutic modalities. We highlight the importance of studies like this in order to identify risk groups and encourage early diagnosis.

Líquen plano pilar: a importância do diagnóstico precoce / Lichen planopilaris: the importance of early diagnosis

O líquen plano pilar é desordem rara da ordem das alopecias cicatriciais primárias. Descreve- se um caso de paciente do sexo feminino, portadora de placas eritêmato-descamativas e plugues foliculares em região frontoparietal bilateralmente, associados a teste de tração positivo. Após biópsia compatível com líquen plano pilar, a paciente foi tratada com prednisona associada a clobetasol, apresentando repilação da área acometida. O tratamento dessa patologia é um desafio devido à escassez de dados sobre eficácia das terapêuticas e constante recidiva. Trata-se de quadro irreversível se não for tratado precocemente. É descrito um caso clássico de líquen plano pilar com boa resposta terapêutica, destacando- -se a importância do diagnóstico precoce, já que em fase inicial a maioria das alopecias cicatriciais é não cicatricial, devendo, por esse motivo, ser manejada como emergência em tricologia.

Lichen planopilaris is a rare disorder that belongs to the primary scarring alopecia type. The present study describes the case of a female patient bearing desquamative erythematous plaques and follicular plugs bilaterally in the frontoparietal region, associated with positive pull test. The biopsy's result was consistent with lichen planopilaris and the patient was treated with prednisone associated with clobetasol, with regrowth of the hair in the affected area. The treatment of this pathology is a challenge due to the lack of data on efficacy of therapies and constant recurrence. The picture is irreversible if not treated early. This paper describes a classic case of a case of lichen planopilaris with good therapeutic response, highlighting the importance of early diagnosis, due to the fact that most cicatricial alopecias do not produce scarring in their initial stage and should for this reason be managed as an emergency in trichology.

Estudo retrospectivo clinicoepidemiológico dos tumores glômicos diagnosticados ao longo de 16 anos em unidade de referência / Clinical epidemiological retrospective study of glomus tumors diagnosed over 16 years in a reference unit

Introdução: O tumor glômico é neoplasia benigna e rara que se apresenta como nódulo solitário e doloroso de localização principalmente subungueal. Apresenta manifestações clínicas características como dor paroxística e sensibilidade à pressão local e ao frio. Objetivo: Realizar levantamento clinicoepidemiológico dos tumores glômicos diagnosticados em unidade de referência em 16 anos. Métodos: Estudo retrospectivo analisando dados clínicos e epidemiológicos de 15 pacientes com diagnóstico de tumor glômico confirmado pelo laudo histopatológico no período de 2000 a 2016. Foram avaliados dados como idade, sexo, localização do tumor, sintomas associados, duração dos sintomas até o diagnóstico, apresentação clínica, tipo histológico e recidiva após a cirurgia. Resultados: Foram diagnosticados 15 casos, em 11 mulheres (73,3%) e quatro homens (26,7%). A média de idade foi 63 anos. A localização mais frequente foi a região subungueal. O tempo médio da duração dos sintomas até o diagnóstico foi de oito anos. Conclusões: Neste estudo, o número de casos de tumor glômico oscilou ao longo desses 16 anos, com média de 0,9 caso/ano. Observou-se maior prevalência em mulheres com mais de 60 anos, na região subungueal e do subtipo histológico glômico sólido.

Introduction: Glomus tumor is a benign and rare neoplasm that appears as solitary and painful nodule, mainly subungual. It presents characteristic clinical manifestations such as paroxysmal pain and sensitivity to local pressure and to cold. Objective: To conduct a clinical epidemiological survey of glomus tumors diagnosed in a reference unit in 16 years. Methods: Retrospective study assessing clinical and epidemiological data of 15 patients with glomus tumor confirmed by histopathological report from 2000 to 2016. Data on age, gender, tumor location, associated symptoms, duration of symptoms until diagnosis, clinical presentation, histological type and recurrence after surgery were analysed. Results: Fifteen cases were diagnosed, 11 in women (73.3%) and four in men (26.7%). Mean age was 63 years. The most frequent location was the subungual region. Mean duration of symptoms until diagnosis was 8 years. Conclusions: In this study, the number of cases of glomus tumor fluctuated throughout these 16 years, with a mean of 0.9 cases/year. A higher prevalence in women over 60 years, subungual region location and solid glomus histologic subtype was observed.

Melanoma maligno: estudo epidemiológico dos casos diagnosticados em unidade de referência em dermatologia em Bauru-sp de 2007 a 2014 / Malignant melanoma: epidemiological study of cases diagnosed at a dermatological reference center in the city of Bauru, in the Brazilian southeast State of São Paulo, between 2007 and 2014

Introdução: No Brasil o melanoma maligno segue tendência mundial de aumento da incidência com redução da gravidade dos casos ao diagnóstico. Objetivo: Utilizar os critérios prognósticos do Grupo Multicêntrico e Multidisciplinar Brasileiro para Estudo do Melanoma aliados a características clínicas para elaborar um perfil clínico e histopatológico dos casos de melanoma. Métodos: Trata-se de estudo transversal e descritivo com análise retrospectiva de prontuários dos pacientes diagnosticados com melanoma em unidade terciária de referência em dermatologia na cidade de Bauru (SP) entre janeiro de 2007 e julho de 2014. Resultados: O sexo feminino correspondeu a 56,2%, a idade variou de 27 a 95 anos com média de 61,4 anos, e em 36% dos casos a lesão foi detectada no exame físico. A maior incidência de acometimento foi nos membros inferiores (23,5%), e o tipo extensivo superficial correspondeu a 79,6% das biópsias. A espessura média do Breslow foi de 2,9mm, e em 28,1% dos casos a lesão era in situ. Conclusões: Delineou-se o seguinte perfil: mulheres, 61 anos, com lesões localizadas em membros inferiores, subtipo extensivo superficial e com indícios de bom prognóstico. Estudos como este adquirem importância por fornecer subsídios para o delineamento de estratégias de abordagens populacionais.

Introduction: The trends of malignant melanoma in Brazil are aligned with those worldwide: increasing incidence with reduced degree of severity at diagnosis. Objective: To use the prognostic criteria of the Grupo Multicêntrico e Multidisciplinar Brasileiro para Estudo do Melanoma (Brazilian Multicenter and Multidisciplinary Group for the Study of Melanoma) combined with clinical characteristics aimed at developing a clinical and histopathological profile of melanoma cases. Methods: A cross-sectional descriptive study was carried out, with the retrospective analysis of medical records of patients diagnosed with melanoma at a tertiary dermatology reference unit in the city of Bauru, in the Brazilian southeast State of São Paulo, between January 2007 and July 2014. Results: Female patients accounted for 56.2%, with ages ranging from 27 to 95 years (Mean = 61.4 years), with a lesion having been detected on physical examination in 36% of cases. The highest incidence of the disease was in the lower limbs (23.5%), with the superficial spreading subtype corresponding to 79.6% of biopsies. The average Breslow thickness was 2.9 mm, and in 28.1% of cases, the lesion was in situ. Conclusions: The following profile emerged: women, 61-years-old, with lesions in the lower limbs, superficial spreading subtype and with evidence of good prognostic. Studies like this are important due to the fact they provide subsidies for the design of strategies to treat the population.

Hanseníase históide símile: desafio diagnóstico / Histoid like leprosy: diagnostic challenge

Em 1963, Wade descreveu a hanseníase histoide, que acometia pacientes previamente tratados com dapsona.Caracteriza-se por lesão com aspecto queloideano, na histopatologia vemos histiócitos fusiformes e um grande número de bacilos. Relata-se caso de hanseníase dimorfa virchoviana com padrão de lesão históide, um verdadeiro desafio diagnóstico, a fim de atentar para manifestações atípicas dessa doença e reforçar a importância da confirmação histológica de casos suspeitos de hanseníase históide.

In 1963, Wade described Histoid Leprosy, that affected patients previously treated with dapsone. This type of leprosy is characterized by keloid-like lesions, in which spindle histiocytes and a large number of bacilli can be seen in the histopathology. A case of borderline lepromatous leprosy with histoid pattern is described, a true diagnostic challenge, in order to attempt to atypical manifestations of the disease and reinforce the importance of histological confirmation in suspected cases of histoid leprosy.