Confiabilidade e validação de um questionário de barreiras e facilitadores percebidos do comportamento sedentário em crianças e adolescentes da América do Sul / Reliability and validation of a questionnaire on perceived barriers and facilitators of sedentary behavior in children and adolescents in South America

Essa dissertação é composta por dois manuscritos: Artigo de Revisão: Validity and reliability of questionnaires that assess barriers and facilitators of sedentary behavior in the pediatric population. A systematic review. - O objetivo de nossa revisão foi avaliar a validade e a confiabilidade de questionários que abordam as barreiras e facilitadores percebidos do comportamento sedentário em crianças e adolescentes de 2 a 19 anos. Além disso, nossa revisão pretendeu identificar os principais fatores associados ao comportamento sedentário. Artigo Original: Confiabilidade e validação de um questionário sobre barreiras e facilitadores percebidos do comportamento sedentário em crianças e adolescentes da América do Sul - (i)Testar a confiabilidade (teste-reteste) de um novo e inovador questionário de barreiras e facilitadores do comportamento sedentário em crianças e adolescentes da América do Sul; (ii) e a validade critério do questionário com o tempo sedentário mensurado por acelerômetro.

Technological advances and prolonged exposure to screens are directly associated with sedentary behavior in the pediatric population. As a consequence, there is an increase in cardiovascular risk factors and obesity, which can accompany the individual in adult life. In this sense, studying the psychometric properties of instruments allows us to understand the level of reliability and validity of the barriers and facilitators of sedentary behavior in the questionnaires, which is important in terms of guiding health prevention strategies and their aggravating factors. Objective: (i) test the reliability (test-retest) of a questionnaire on barriers and facilitators of sedentary behavior in children and adolescents in South America; (ii) test the predictive validity of the questionnaire with sedentary time measured by accelerometry. Methodology: The SAYCARE Study is an observational multicenter feasibility study in a sample of children and adolescents aged 3 to 18 years (children: n= 237 adolescents n= 273. This pilot was developed in São Paulo and six other cities in North America South: Teresina (Brazil), Buenos Aires (Argentina), Santiago (Chile), Montevideo (Uruguay), Lima (Peru) and Medellín (Colombia). The questionnaire was applied twice with an interval of two weeks and the behaviors were reported by the parents for children and self-reported for adolescents. The accelerometer was used for at least 3 days, including at least one weekend day. We will compare sedentary time values using accelerometers by time quartiles of sedentary time measured. For analysis statistics, descriptive analyzes were used (mean, median, standard deviation and proportions) questionary and the agreement was mild and for the adolescents the reliability was moderate with higher agreement as well. For the factor analysis, two factors were obtained (children: Factor 1- 0.25992 to 0.34477 and Factor 2 -0.27831 to 0.35565) and (adolescents Factor 1 from 0.26403 and Factor 2 from 0.29266 to 0.32431). Spearman's correlation showed low to moderate values in comparison between Q1 and the use of accelerometry data.

Validity and Reliability of Questionnaires That Assess Barriers and Facilitators of Sedentary Behavior in the Pediatric Population: A Systematic Review.

We systematically reviewed the literature about the validity and reliability of barriers and facilitators of sedentary behavior questionnaires for children and adolescents, considering accelerometers as the reference method. We included studies that assessed the agreement between the barriers and facilitators of sedentary behavior through a questionnaire and an objective measure (e.g., accelerometry). We searched four electronic databases (MEDLINE/PubMed, CINAHL, Web of Science, and SCOPUS): these databases were searched for records from inception to 5 March 2021, and updated to November 2022. The search strategy used the following descriptors: children and adolescents; barriers or facilitators; questionnaires; accelerometers; and validation or reliability coefficient. Studies identified in the search were selected independently by two reviewers. The inclusion criteria were: (i) population of children and adolescents, (ii) original studies, (iii) subjective and objective measurement methods, (iv) studies that report validity or reliability, and (v) population without specific diseases. Seven studies were eligible for our review. The main exclusion reasons were studies that did not report validity or reliability coefficients (56.6%) and non-original studies (14.5%). The participants' ages in the primary studies ranged from 2 to 18 years. Cronbach's alpha coefficient was the most reported reliability assessment among the eligible articles, while Pearson and Spearman's coefficients were prevalent for validity. The reliability of self-report questionnaires for assessing sedentary behavior ranged from r = 0.3 to 1.0. The validity of the accelerometers ranged from r = -0.1 to 0.9. Family environment was the main factor associated with sedentary behavior. Our findings suggest that questionnaires assessing the barriers and facilitators of sedentary behavior are weak to moderate. PROSPERO Registration (CRD42021233945).

Automated Identification of Dental Implants Using Artificial Intelligence.

PURPOSE: To develop and evaluate the accuracy of a computer-assisted system based on artificial intelligence for detecting and identifying dental implant brands using digital periapical radiographs. MATERIALS AND METHODS: A total of 1,800 digital periapical radiographs of dental implants from three distinct manufacturers (f1 = 600, f2 = 600, and f3 = 600) were split into training dataset (n = 1,440 [80%]) and testing dataset (n = 360 [20%]) groups. The images were evaluated by software developed by means of convolutional neural networks (CNN), with the aim of identifying the manufacturer of the dental implants contained in them. Accuracy, sensitivity, specificity, positive and negative predictive values, and the receiver operating characteristic (ROC) curve were calculated for detection and diagnostic performance of the CNN algorithm. RESULTS: At the final epoch (25), system accuracy values of 99.78% were obtained for group training data, 99.36% for group testing data, and 85.29% for validation data. The latter value corresponded to the actual accuracy of carrying out the system learning process. CONCLUSION: This study demonstrated the effectiveness of CNN for identifying dental implant manufacturers, which was proven to be a precise method of great clinical significance.

Prevalence and characterization of maxillary sinus septa in a brazilian population.

BACKGROUND: The aim of this study was to assess the anatomic aspects of the maxillary sinus septa, by means of computed tomography images, in a Brazilian population. The results might be of clinical significance in sinus lift surgery planning. MATERIAL AND METHODS: In the study, 123 computed tomographs obtained from a private radiology clinic were used. They were analyzed by a single, trained and calibrated observer in order to evaluate the presence, quantity, localizations, dimensions, orientations and different characteristics in dentate, partially edentulous and completely edentulous individuals of the sinus septa. RESULTS: Of the individuals analyzed, 26% had a septum in the maxillary sinus, with 59.6% being classified as complete, 44.2% showed prevalence for the middle region of the maxillary sinus. There was no statistically significant difference between the right and left sides (p>0.05). CONCLUSIONS: The majority of patients in the sample analyzed presented to septa in the maxillary sinuses, and when septa were present, a higher number of occurrence was noted in the middle region of the maxillary sinus. (This region is normally the choice of sinus lift surgery). There was no predilection relative to age, sex and type of dentition. Key words:Multislice computed tomography, maxillary antrum, anatomic variation.

Efeito do laser de baixa intensidade como coadjuvante na reparação óssea de dente com perfuração radicular e lesão perirradicular: relato de caso clínico, com 12 anos de acompanhamento / Effect of low intensity laser supporting bone repair on a tooth with root perforation and periradicular lesion: case report and 12 years follow-up

Introdução: O laser em baixa intensidade apresenta propriedades que podem ser efetivas no tratamento endodôntico, como a capacidade reparadora, a atuação antimicrobiana e o auxílio à proliferação celular. Objetivo: Descrever, por meio do relato de um caso clínico, a ação do laser em baixa intensidade como coadjuvante na reparação óssea de uma perfuração radicular e lesão perirradicular em um elemento dentário com canais tratados, sendo realizado retratamento endodôntico apenas do canal mesiovestibular, utilizando-se hidróxido de cálcio como medicação intracanal e laser em baixa intensidade. Os demais canais não foram submetidos a retratamento, apesar de apresentarem lesão perirradicular. Resultados: O laser em baixa intensidade mostrou-se efetivo como auxiliar no processo de reparação óssea restituindo, ad integrum, o osso interradicular e as lesões perirradiculares das raízes mesial e distal após acompanhamento de 12 anos. Conclusões: O laser em baixa intensidade pode ser utilizado como coadjuvante ao tratamento de perfurações, demonstrando sucesso em longo prazo (AU).

Introduction: Low intensity laser has properties that may be effective in endodontic treatment, such as restorative capacity, antimicrobial performance and cell proliferation. Methods: This report describes the action of low intensity laser as an adjunct to bone repair of a root perforation and peri-radicular lesion in a tooth submitted to endodontic treatment, in which endodontic retreatment was performed only in the mesiobuccal canal using calcium hydroxide as intracanal medication and low level laser. The other canals were not submitted to retreatment, in spite of having peri-radicular lesions. Results: The low-intensity laser was effective as an adjunct to the bone repair process, restoring ad-integrum, interradicular bone and the peri-radicular lesions of the mesial and distal roots, after 12 years of follow-up. Conclusion: The laser at low intensity can be used as a coadjuvant to the treatment of perforations, demonstrating long-term success (AU).

Case Reports of a New Method for Differential Diagnosis of Calcified Carotid Artery Atheroma.

Introduction. Early diagnosis of calcified atheromas may decrease morbidity and mortality caused by brain and cardiovascular diseases, in which atherosclerosis is the main etiological factor of these pathologies. Dental examinations with the aim of detecting this pathology have been in progress since 1981, such as panoramic radiography, considered the most widely studied method for this diagnosis. However, some limitations of this exam have been reported with reference to inability to visualize the cervical region and difficulty of establishing a precise diagnosis because of many structures and calcifications that have similar radiographic characteristics. Case Report. The present study to describe a dental radiographic technique for establishing the differential diagnosis of calcified atheromas regarding other calcifications and reporting 3 clinical cases that demonstrate its effectiveness in different clinical situations. Discussion. Manzi Projection can promote a differential diagnosis of calcified atheromas in dental practice and consequently subsidize the clinician for referring the patient to the physician.

A realização do sistema supersérie com diferentes segmentos corporais não impacta no volume e percepção subjetiva de esforço / The superset system performed using different limbs does not impact on volume and rating of perceived exertion / El sistema supersérie realizado con diferentes segmentos corporais no impacta en el volumen y percepción subjetiva del esfuerzo

O objetivo do estudo foi comparar os sistemas tradicional (TRAD) e supersérie (SS) quanto ao número de repetições (volume) e percepção subjetiva de esforço (PSE) nos exercícios supino e extensão de joelhos. Doze homens treinados realizaram de forma randomizada (medidas repetidas) os protocolos em sistemas TRAD e SS (4 séries com pausas de 2 minutos, intensidade de 10 repetições máximas). No sistema SS, cada série do exercício banco extensor foi realizada durante a pausa do exercício supino. Não houve diferença significativa no volume (TRAD supino - série 1: 16,1 ± 1,6; série 2: 10,9 ± 2,1; série 3: 7,8 ± 2,3; série 4: 7,0 ± 2,0; TRAD extensão de joelhos ­ série 1: 13,1 ± 2,5; série 2: 11,0 ± 2,0; série 3: 9,1 ± 1,7; série 4: 7,6 ± 1,6; SS supino ­ série 1: 16,3 ± 2,3; série 2: 10,9 ± 1,6; série 3: 7,8 ± 1,9; série 4: 6,1 ± 1,4; SS extensão de joelhos ­ série 1: 13,8 ± 1,8; série 2: 11,2 ± 1,6; série 3: 8,8 ± 1,7; série 4: 7,0 ± 1,7) e na PSE (TRAD supino - mediana série 1: 15,0; mediana série 4: 19,5; TRAD extensão de joelhos - mediana série 1: 17,0; mediana série 4: 19,5; SS supino - mediana série 1: 16,5; mediana série 4: 20,0; SS extensão de joelhos - mediana série 1: 17,5; mediana série 4: 19,5) entre os protocolos. Verificou-se redução do volume e aumento da PSE no decorrer das séries em ambas situações experimentais. Considerando a similaridade dos resultados obtidos entre os sistemas SS e TRAD, a aplicação de SS torna-se uma alternativa eficiente para a redução do tempo de treinamento.

The objective of the study was to compare the number of repetitions (volume) and the rating of perceived exertion (RPE) in the bench press and knee extension exercises when performing Traditional (TRAD) and Superset (SS) training systems. Twelve trained men randomly performed (repeated measurements) the TRAD and SS systems (4 sets and 2-minute rest intervals, intensity of 10 max repetitions). In the SS system, each set of the knee extension was performed during the interval of the bench press. There was no significant difference in volume (TRAD bench press ­ set 1: 16,1 ± 1,6; set 2: 10,9 ± 2,1; set 3: 7,8 ± 2,3; set 4: 7,0 ± 2,0; TRAD knee extension ­ set 1: 13,1 ± 2,5; set 2: 11,0 ± 2,0; set 3: 9,1 ± 1,7; set 4: 7,6 ± 1,6; SS bench press ­ set 1: 16,3 ± 2,3; set 2: 10,9 ± 1,6; set 3: 7,8 ± 1,9; set 4: 6,1 ± 1,4; SS knee extension ­ set 1: 13,8 ± 1,8; set 2: 11,2 ± 1,6; set 3: 8,8 ± 1,7; set 4: 7,0 ± 1,7) and PSE (TRAD bench press median set 1: 15,0; median set 2: 19,5; TRAD knee extension ­ median set 1: 17,0; median set 4: 19,5; SS bench press ­ median set 1:16,5; median set 4: 20,0; SS knee extension ­ median set 1: 17,5; median set 4: 19,5) between the protocols. There was a reduction in volume and increase of PSE during the sets in both experimental situations. Considering the similarity of the results obtained between the SS and TRAD systems, SS application becomes an efficient alternative for decreasing training time.

El objetivo del estudio fue comparar los sistemas Tradicional (TRAD) y Supersérie (SS) en cuanto al número de repeticiones (volumen) y percepción subjetiva de esfuerzo (PSE) en los ejercicios press de banca (PB) y extensión de rodillas (ER). Doce hombres entrenados realizaron de forma aleatorizada (mediciones repetidas) los sistemas TRAD y SS (4 series; pausas de 2 minutos, intensidad de 10 repeticiones máximas). En el sistema SS, cada serie de ER se realizó durante la pausa de PB. No hubo diferencia en el volumen (TRAD press de banca - serie 1: 16,1 ± 1,6; serie 2: 10,9 ± 2,1; serie 3: 7,8 ± 2,3; serie 4: 7,0 ± 2,0; TRAD extensión de rodillas ­ serie 1: 13,1 ± 2,5; serie 2: 11,0 ± 2,0; serie 3: 9,1 ± 1,7; serie 4: 7,6 ± 1,6; SS press de banca ­ serie 1: 16,3 ± 2,3; serie 2: 10,9 ± 1,6; serie 3: 7,8 ± 1,9; serie 4: 6,1 ± 1,4; SS extensión de rodillas ­ serie 1: 13,8 ± 1,8; serie 2: 11,2 ± 1,6; serie 3: 8,8 ± 1,7; serie 4: 7,0 ± 1,7) e na PSE (TRAD press de banca - mediana serie 1: 15,0; mediana serie 4: 19,5; TRAD extensión de rodillas - mediana serie 1: 17,0; mediana serie 4: 19,5; SS press de banca - mediana serie 1: 16,5; mediana serie 4: 20,0; SS extensión de rodillas - mediana serie 1: 17,5; mediana serie 4: 19,5) entre los protocolos. Se verificó reducción del volumen y aumento de la PSE en el curso de las series en ambas situaciones. Considerando la similitud de los resultados obtenidos entre los sistemas SS y TRAD, la aplicación de SS se convierte en una alternativa eficiente para la reducción del tiempo de entrenamiento.

Polydimethylsiloxane/nano calcium phosphate composite tracheal stents: Mechanical and physiological properties.

In this study, we report the production and characterization of tracheal stents composed of polydimethylsiloxane/nanostructured calcium phosphate composites obtained by reactive synthesis. Tracheal stents were produced by transfer molding, and in vivo tests were carried out. PDMS was combined with H3 PO4 and Ca(OH)2 via an in situ reaction to obtain nanoparticles of calcium phosphate dispersed within the polymeric matrix. The incorporation of bioactive inorganic substances, such as calcium phosphates, improved biological properties, and the in situ reaction allowed tight coupling of particles to the matrix. Results showed the presence of the nanoparticles of DCPA and CDHA. The porosity generated during mixing decreased the tensile strength and tear properties. Composites presented higher values of cell viability compared with those for PDMS. In vivo tests indicated the presence of inflammatory tissue 30 days after implantation in both cases. Thus, the present biomaterial shows potential for application in tracheal disease, however further evaluation is needed. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2018. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 545-553, 2019.

Terceiro molar impactado invertido: série de casos retrospectivos e relato de dois casos / Inverted impacted third molars: retrospective case series and two case reports

Dente impactado é todo aquele que sofre falha no seu processo eruptivo, ficando sob tecido duro e/ou mole. Dentro da classificação de tais dentes existem os terceiros molares invertidos, poucos descritos na literatura. O objetivo deste artigo é apresentar dois casos de terceiros molares maxilares impactados invertidos, diagnosticados através de exames de rotina odontológica e analisar relatos na literatura sobre terceiros molares invertidos. Foram selecionados artigos anexados à base de dados Pubmed, através de busca pelo termo "Inverted Third Molar", não havendo restrição quanto ao ano de publicação e idioma. Terceiros molares invertidos apresentam rara prevalência, sendo este relato um complemento à literatura previamente publicada(AU)

Impacted tooth is anyone who suffers failure in eruptive process, getting under hard and/or soft tissue. According to this classification there are the third inverted molars, few described in the literature. The aim of this article is to present two cases of inverted impacted maxillary third molars, diagnosed through routine dental examinations and to analyze reports in the literature about inverted third molars. We selected articles attached to the Pubmed database, searching for the term "Inverted Third Molar", there being no restriction regarding the year of publication and language. Inverted third molars present a rare prevalence, being this report a complement to previously published literature(AU)

The Manzi projection: an imaging method used in dentistry for differential diagnosis of atheroma / Projeção de Manzi: um método odontológico para diagnóstico diferencial de ateroma

ABSTRACT Atherosclerosis is a pathology of great importance worldwide, because of its direct relationship with cerebrovascular events, resulting in high morbidity and mortality rates. The possibility of atheromas being identified by means of panoramic radiography is consolidated in literature; however, limitations have been reported. Thus, the aim of the present clinical case was to demonstrate the possibility of using Manzi's Projection, which is a technique that enables visualization of the carotid artery trajectory without superimpositions of other anatomic structures, capable of promoting differential diagnosis of calcified atheromas in the carotid artery during dental exams.

RESUMO A aterosclerose representa uma patologia de grande importância mundial devido à relação direta com as doenças cerebrovaculares, resultando em altos índices de morbimortalidade. A possibilidade de identificação destas placas ateromatosas através da radiografia panorâmica está consolidada na literatura, sendo também relatadas suas limitações. Com intutito de possibilitar um diagnóstico diferencial de ateromas na prática odontológica, a Projeção de Manzi consiste numa técnica ântero-posterior que possibilita uma visualização sem sobreposições do trajeto carotídeo. O presente estudo tem por objetivo relatar um caso clínico demonstrando as possibilidades diagnósticas dos exames odontológicos na detecção de ateromas calcificados na artéria carótida.

Combined Bone Marrow-Derived Mesenchymal Stromal Cell Therapy and One-Way Endobronchial Valve Placement in Patients with Pulmonary Emphysema: A Phase I Clinical Trial.

One-way endobronchial valves (EBV) insertion to reduce pulmonary air trapping has been used as therapy for chronic obstructive pulmonary disease (COPD) patients. However, local inflammation may result and can contribute to worsening of clinical status in these patients. We hypothesized that combined EBV insertion and intrabronchial administration of mesenchymal stromal cells (MSCs) would decrease the inflammatory process, thus mitigating EBV complications in severe COPD patients. This initial study sought to investigate the safety of this approach. For this purpose, a phase I, prospective, patient-blinded, randomized, placebo-controlled design was used. Heterogeneous advanced emphysema (Global Initiative for Chronic Lung Disease [GOLD] III or IV) patients randomly received either allogeneic bone marrow-derived MSCs (108 cells, EBV+MSC) or 0.9% saline solution (EBV) (n = 5 per group), bronchoscopically, just before insertion of one-way EBVs. Patients were evaluated 1, 7, 30, and 90 days after therapy. All patients completed the study protocol and 90-day follow-up. MSC delivery did not result in acute administration-related toxicity, serious adverse events, or death. No significant between-group differences were observed in overall number of adverse events, frequency of COPD exacerbations, or worsening of disease. Additionally, there were no significant differences in blood tests, lung function, or radiological outcomes. However, quality-of-life indicators were higher in EBV + MSC compared with EBV. EBV + MSC patients presented decreased levels of circulating C-reactive protein at 30 and 90 days, as well as BODE (Body mass index, airway Obstruction, Dyspnea, and Exercise index) and MMRC (Modified Medical Research Council) scores. Thus, combined use of EBV and MSCs appears to be safe in patients with severe COPD, providing a basis for subsequent investigations using MSCs as concomitant therapy. Stem Cells Translational Medicine 2017;6:962-969.

Solution and high-pressure NMR studies of the structure, dynamics, and stability of the cross-reactive allergenic cod parvalbumin Gad m 1.

Beta-parvalbumins from different fish species have been identified as the main elicitors of IgE-mediated reactions in fish-allergic individuals. Here, we report for the first time the NMR determination of the structure and dynamics of the major Atlantic cod (Gadus morhua) allergen Gad m 1 and compare them with other known parvalbumins. Although the Gad m 1 structure and accessibility of putative IgE epitopes are similar to parvalbumins in mackerel and carp, the charge distribution at the putative epitopes is different. The determination of the Gad m 1 structure contributes to a better understanding of cross-reactivity among fish parvalbumins. In addition, the high-pressure NMR and temperature variation experiments revealed the important contribution of the AB motif and other regions to the protein folding. This structural information could assist the future identification of hot spots for targeted mutations to develop hypoallergenic Ca(2+) -free forms for potential use in immunotherapy.

Uma contribuição da semiótica para a comunicação visual na área da saúde / A contribution from semiotics towards visual communication within the field of healthcare / Uma contribución de la semiótica para la comunicación visual en el área de la salud

An analysis model proposed by Jean-Marie Floch is presented as a possible tool for creating and evaluating visual communication within the field of healthcare, and in particular for educational campaigns. Starting from introductory questions relating to semiotics, certain concepts common to discursive semiotics and esthetic semiotics are laid out, as postulated by Floch. A model based on the semantic opposites of euphoria and dysphoria is then presented. The paper ends by demonstrating the application of the model to a poster from a preventive campaign against smoking-related diseases.

Apresenta-se um modelo de análise proposto por Jean-Marie Floch como possibilidade para a criação e avaliação da comunicação visual na área da saúde, especialmente em campanhas educativas. Parte-se de questões introdutórias acerca da semiótica, expõem-se alguns conceitos comuns à semiótica discursiva e a semioestética, conforme postulado por Floch, e apresenta-se o modelo que tem a euforia e a disforia como oposição semântica de base. Ao final, mostra-se a aplicação do modelo em um cartaz de uma campanha preventiva contra doenças provocadas pelo fumo.

Se presenta un modelo de análisis propuesto por Jean-Marie Floch como posibilidad para la creación y valuación de la comunicación visual en el área de la salud, especialmente en campañas educativas. Se parte de cuestiones introductorias acerca de la semiótica, se exponen algunos conceptos comunes a la semiótica discursiva y a la semiótica estética, tal como postula Floch y se presenta el modelo que tiene la euforia y la ansiedad como oposición semántica de base. Al final se muestra la aplicación del modelo en el cartel de una campaña preventiva contra enfermedades provocadas por el tabaco.