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J Infect Dis ; 169(5): 1035-41, 1994 May.
Artigo em Inglês | MEDLINE | ID: mdl-8169388

RESUMO

An epidemic of Shigella dysenteriae type 1 infections has affected Africa since 1979. Reported dysentery cases increase sharply in Burundi during September through December. Of stool samples from 189 patients reporting bloody diarrhea in November 1990, a pathogen was identified in 123 (65%). The pathogen was S. dysenteriae type 1 in 82 (67%). All S. dysenteriae type 1 isolates were resistant to ampicillin, chloramphenicol, nalidixic acid, streptomycin, sulfisoxazole, tetracycline, and trimethoprim-sulfamethoxazole. Thirty-two specimens (26%) yielded other Shigella species. Patients with S. dysenteriae type 1 were more likely than those with other Shigella infections to have abdominal pain, "lots of blood" in the stool, blood in the stool specimen examined by the interviewer, recent contact with a person with dysentery, or recent antimicrobial treatment. Thus, the seasonal increase in dysentery was due largely to multidrug-resistant S. dysenteriae type 1, clinical and epidemiologic features may predict such infection, and efforts to control this epidemic must focus on preventing transmission.


Assuntos
Surtos de Doenças , Disenteria Bacilar/epidemiologia , Shigella dysenteriae , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Burundi/epidemiologia , Estudos de Casos e Controles , Criança , Pré-Escolar , Resistência Microbiana a Medicamentos , Disenteria Bacilar/microbiologia , Disenteria Bacilar/fisiopatologia , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Estações do Ano , Shigella dysenteriae/classificação , Shigella dysenteriae/efeitos dos fármacos
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