Environmental carcinogen exposure and lifestyle factors affecting cancer risk in Qatar: findings from a qualitative review.

To meet the country's health goals for 2011-2016, a qualitative review of exposure to risk factors for cancer in Qatar was conducted in 2013. The review included exposure to environmental agents carcinogenic to humans (International Agency for Research on Cancer classification), as well as lifestyle factors known to affect cancer risk. Information from all available sources was assembled and reviewed. The levels of particulate matter reported in Qatar were in the upper range of ambient air pollutants reported internationally, and may influence the country's future lung cancer burden. The limited data on occupational exposure suggests that the greatest risks for workers in the construction industry are likely to be from environmental dust and related air pollutants. The greatest cancer risks for Qatari nationals may be lifestyle factors, particularly obesity, physical inactivity and tobacco use. Extended monitoring of the composition of and human exposure to air pollutants is recommended.

Environmental carcinogen exposure and lifestyle factors affecting cancer risk in Qatar:findings from a qualitative review

To meet the country's health goals for 2011-2016,a qualitative review of exposure to risk factors for cancer in Qatar was conducted in 2013.The review included exposure to environmental agents carcinogenic to humans [International Agency for Research on Cancer classification], as well as lifestyle factors known to affect cancer risk.Information from all available sources was assembled and reviewed.The levels of particulate matter reported in Qatar were in the upper range of ambient air pollutants reported internationally,and may influence the country's future lung cancer burden.The limited data on occupational exposure suggests that the greatest risks for workers in the construction industry are likely to be from environmental dust and related air pollutants.The greatest cancer risks for Qatari nationals may be lifestyle factors,particularly obesity,physical inactivity and tobacco use.Extended monitoring of the composition of and human exposure to air pollutants is recommended

Afin d'atteindre les objectifs de sante fixes par le pays pour 2011-2016,une analyse qualitative de L'exposition aux facteurs de risque de cancer au Qatar a ete conduite en 2013.L'analyse incluait L'exposition aux agents environnementauxcancerogenes pour Thomrne [classification du Centre international de recherchesur le cancer]ainsi que les facteurs lies au mode de vie connus pour augmenter le risque de cancer.Des informations ont ete rassemblees a partir de toutes les sources disponibles et ont fait Tobjet d'un examen.Les niveaux de particules rapportes au Qatar se situaient dans la fourchette haute des polluants atmospheriques ambiants au niveau mondial,ce qui pourrait influencer la charge future du cancer du poumon dans le pays.Le nombre IImite de donnees sur 1'exposition professionnelle suggere que les risques ies plus importants pour les professionnels de I'industrie du batiment seraient lies a la poussiere environnementale et aux polluants atmospheriques qu'elle contient.Les risques de cancer les plus eleves pour les Qatariens proviendraient de facteurs associes aux modes de vie,en particulier I'obesite,la sedentarite et le tabagisme.Un suivi accru de la composition des polluants atmospheriques et de 1'exposition de I'homme a ces derniers est recommande

Blood serum characteristics of newborn pigs: comparison of unaffected pigs with pigs belonging to five mortality groups.

The blood serum levels of glucose, hemoglobin, insulin, cortisol, albumin, alpha-fetoprotein, alpha 2-macroglobulin f and s, alpha 2-antitrypsin inhibitor and alpha 1-protease inhibitor were determined at birth in 5 clinically and morphologically identified mortality groups of pigs. These were compared with the levels observed in unaffected, apparently normal newborn unsuckled pigs. The blood serum profile of the pigs in the stillborn intra partum, weak, splayleg and trauma groups, respectively, as well as that of clinically normal splayleg littermates, differed significantly from that of the unaffected pigs. This was especially true for the levels of hemoglobin and the two macroglobulins. The importance of placental insufficiency causing chronic episodes of hypoxia which ultimately lead to a disturbance in organ development in the etiology of the mortality groups is discussed.

Intestinal macromolecular transmission in underprivileged and unaffected newborn pigs: implication for survival of underprivileged pigs.

Passive immunisation of the newborn pig depends upon intestinal macromolecular transmission to the blood, which ceases within 18 to 36 hours after birth in fed pigs. Macromolecular transmission in newborn, unsuckled pigs was tested by gavage feeding bovine serum albumin and fluorescein isothiocyanate-labelled dextran (molecular weight 70 kDa) together with sow colostrum. Serum levels measured four hours after feeding showed that underweight pigs under 1.0 kg, both apparently normal and weak, had a greater capacity for transmission than did apparently normal pigs over 1.0 kg (unaffected). Weak pigs 1.0 kg, or more, had a transmission equivalent to that of unaffected pigs, indicating that they may be otherwise normal animals affected by birth. Splayleg pigs and their clinically unaffected littermates also showed a greater capacity for transmission than unaffected pigs; splayleg apparently involves the entire litter, although the expression of the syndrome varies. The capacity for transmission in the unaffected pig increased with litter size and decreased with an increase in weight and age after birth. In addition, it was shown that transmission was greater in pigs with higher glucose, insulin and alpha-fetoprotein concentrations and lower haemoglobin, cortisol and alpha 2-macroglobulin f concentrations at birth. It was concluded that immature pigs have a greater capacity for intestinal macromolecular transmission at birth than unaffected pigs over 1.0 kg. Since the capacity for macromolecular transmission decreases with age, the probability of their survival depends very much on the husbandry practices in the herd.