RESUMO
OBJECTIVE: The exact pathogenic mechanism underlying the thrombotic tendency in retinal vein occlusion (RVO) is still not fully established. We investigated relationship between platelet indices including mean platelet volume (MPV) and platelet count in RVO patients compared to control group. PATIENTS AND METHODS: Forty six patients (19 female, 27 male) diagnosed as RVO were included in the study. Forty-six subjects (26 female, 20 male) served as controls. Patients were evaluated by careful biomicroscopic examination using a fundus contact lens and fluorescein angiography. Blood samples for total blood count with MPV were obtained after overnight fasting from the antecubital vein. RESULTS: The mean platelet volume was 8.11 ± 1.15 fl in RVO group. It was 8.68 ± 0.98 fl in controls. When compared, the mean MPV was significantly lower in RVO patients (p < 0.05). The mean platelet volume was also significantly lower in branch retinal vein occlusion group in comparison to controls (7.92 ± 1.19 fl. versus 8.68 ± 0.98 fl.) (p < 0.05). CONCLUSIONS: MPV was significantly lower in patients with RVO than control group. MPV does not seem to be a potentially useful biomarker for prediction of RVO.
Assuntos
Oclusão da Veia Retiniana/sangue , Estudos de Casos e Controles , Jejum/sangue , Feminino , Angiofluoresceinografia , Humanos , Masculino , Volume Plaquetário Médio , Pessoa de Meia-Idade , Contagem de Plaquetas , Oclusão da Veia Retiniana/patologiaRESUMO
PURPOSE: To evaluate the thickness of the retinal nerve fiber layer (RNFL) in subjects with congenital red-green color vision deficiency (CVD). METHODS: This study included 20 healthy subjects with congenital red-green CVD and 22 healthy subjects with normal color vision. After Ishihara test and examinations visual field by automated perimetry, all individuals underwent scanning laser polarimetry to measure the thickness of the RNFL. RESULTS: All scanning laser polarimetry parameters related to RNFL thickness were found to be similar in subjects with congenital CVD and normal color vision (p>0.05). CONCLUSIONS: This is the first report suggesting normal thickness of the RNFL in subjects with congenital red-green CVD.