[Myocardial infarction in patients with non-insulin-dependent diabetes mellitus and dependence of the quality of life on the individual psychological type]. / Infarkt miokarda u bol'nykh insulinnezavisimym sakharnym diabetom i zavisimost' kachestva zhizni ot psikhologicheskikh osobennostei lichnosti.

AIM: To examine clinical features, complications, short- and long-term outcomes of myocardial infarction (MI) as well as quality of life (QL) in patients with non-insulin-dependent diabetes mellitus (NIDDM), to analyze relations between the above parameters and psychologic personal traits of the patients. MATERIAL AND METHODS: The study entered 240 NIDDM patients with MI (the test group) and 260 control nondiabetic MI patients. The examination was made using standard techniques and AMPI. RESULTS: An anginal variant of initial MI in NIDDM patients was registered significantly less frequently than in the controls (76.7 vs 88.2%). The asthmatic variant occurred in 16.3 and 4.6% of the cases, respectively. In MI, NIDDM patients developed preinfarction and postinfarction angina pectoris less often than control patients (20 and 12.1% vs 71.9 and 25.7%, respectively). Mean psychological profile was high by AMPI scales 1, 2 and 6 in NIDDM patients, by scales 1, 3 and 8 in control patients. CONCLUSION: Pain syndrome in anginal initial MI in NIDDM patients is less pronounced and becomes weaker with growing duration of diabetes. Concomitant diabetes mellitus has an insignificant influence on deterioration of quality of life in the postinfarction period.

[Fatal outcome of acute myocardial infarction in men and women]. / Letal'nye iskhody pri ostrom infarkte miokarda sredi muzhchin i zhenshchin.

An epidemiologic study of the outcomes of acute myocardial infarction, carried out according to the WHO Register of Acute Myocardial Infarction, demonstrated that overall mortality rates are similar for men and women between 20 and 69 years of age. Prehospital mortality was significantly higher in men, as compared to women, while the opposite was true for hospital mortality. Overall, prehospital and hospital mortality rates were relatively high in the younger patients, both male and female, an evidence of a more severe course of acute myocardial infarction at a younger age.

[Dynamics of changes in the levels of myoglobin and anti-myoglobin autoantibodies in the blood serum of patients with myocardial infarction]. / Dinamika izmenenii kontsentratsii mioglobina i autoantitel k mioglobinu v syvorotke krovi bol'nykh s infarktom miokarda.

The mean level of myoglobin and autoantibodies to myoglobin in the blood of healthy donors was 77.57 +/- 8.17 ng/ml and 18.01 +/- 1.85 micrograms/ml respectively. The level of myoglobin in the blood of patients with primary transmural myocardial infarction was rapidly increased, reaching its maximum in 9-12 h and returning to normal in 9 days. The mean level of autoantibodies was decreased in the first 66 h and got back to normal by the 6th day of disease. In primary large focal nontransmural myocardial infarction the concentration of myoglobin in the blood of patients was also increased, reaching its maximum in 3-9 h and returning to normal by the end of the 2nd day after onset of an angina attack. A decrease in the level of autoantibodies to myoglobin was observed up to the 18th day of disease. The peculiarity of repeated large focal nontransmural myocardial infarction was a two-peak curve of changes in a MG level with maximum levels in 9-12 and 21-24 h after onset of a pain attack. Final normalization of the level of myoglobin in the blood of patients of this group occurred in 69 h. The concentration of autoantibodies to myoglobin was more than once decreased up to the 6th day of disease. The results obtained showed that groups of examinees differed in the time course of changes in the level of myoglobin and autoantibodies to myoglobin. Such differences can be used for diagnostic purposes.

[Incidence of sudden death cases in acute coronary insufficiency and acute myocardial infarction at the pre-hospital stage in Krasnoyarsk]. / Chastota sluchaev vnezapnoi smerti ot ostroi koronarnoi nedostatochnosti i ostrogo infarkta miokarda na dogospital'nom etape v Krasnoiarske.

The impact of improvements in prehospital cardiologic service on total and prehospital mortality associated with acute coronary insufficiency (ACI) and acute myocardial infarction (AMI) and the causes of fatal outcomes is illustrated by a study based on the acute myocardial infarction register involving populations from two city districts between 20 and 69 years of age. Prehospital mortality caused by ACI and AMI is shown to decline with the progress of cardiologic care. The decline is attributed to reduced incidence of some causes of death, such as heart failure and cardiogenic shock. Sudden coronary death (85.1%) remains the principal cause of prehospital mortality.

[Dynamics of pre-hospital lethality in acute coronary insufficiency and myocardial infarct in Krasnoyarsk during 1963-1975]. / Dinamika dogospital'noi letal'nosti ot ostroi koronarnoi nedostatochnosti i infarkta miokarda v Krasnoiarske za 1963-1975 gg.

The data on the dynamics of prehospital mortality in acute coronary failure (ACF) and myocardial infarction (MI) depending on the improvement in medical service in the prehospital stage of treatment are presented. The research showed that prehospital mortality in ACF and MI accounts for 75% of the total mortality. Among deaths registered in the prehospital stage 73.7% were sudden. As the result of improvements in prehospital medical service due to the training of physicians of the emergency medical service, the organization of cardiologic emergency aid teams, clinico-pathologic conferences held at the emergency medical service stations, etc. extrahospital mortality dropped from 45.6% (1963) to 26.2% (1975) with simultaneous drop in total mortality from 61.9% (1963) to 37.4% (1975).