RESUMO
For the purpose to determine the clinic-pathogenetic efficacy of cycloferon liniment in the combined therapy of periodontitis of patients with subclinical stage of HIV-infection medical examination and treatment of 40 patients was carried out. It was established that use of liniment cycloferon in the combined treatment of patients with subclinical stage of HIV-infection allowed to accelerate process of normalization of lipid peroxidation parameters and antioxidant potential of blood, to decrease infection load (herpes symplex virus I, Candida albicans, Staphylococcus aureus) in parodontal recess and evidence of local inflammation with reduction of activity of the tumours necrosis factor and interleukin 1beta, what provided acceleration of recuperation processes, lowering the frequency of parodontitis relapses.
Assuntos
Acridinas/uso terapêutico , Infecções por HIV/complicações , Indutores de Interferon/uso terapêutico , Periodontite/tratamento farmacológico , Adulto , Candida albicans/isolamento & purificação , Chlamydia trachomatis/isolamento & purificação , Citomegalovirus/isolamento & purificação , Quimioterapia Combinada , Feminino , Herpesvirus Humano 1/isolamento & purificação , Humanos , Linimentos , Masculino , Periodontite/complicações , Periodontite/microbiologia , Adulto JovemRESUMO
In order to determine cycloferon liniment clinical-pathogenetic efficacy in comprehensive parodontitis therapy examination and treatment of 80 patients was done. It was determined that the cycloferon liniment use in comprehensive treatment of patients with parodontitis let to reduce infectious load in parodontal pockets and local inflammation intensity, to normalize the secretory immunoglobulin level and immune status indices that provided speed up of healing process and reduction relapse frequency.