[Segregation and genetic dispersion analysis of the pedigrees of breast cancer patients in the Kiev region]. / Segregatsionnyi i genetiko-dispersionnyi analiz rodoslovnykh bol'nykh rakom molochnoi zhelezy kievskogo regiona.

Complex clinical-genealogical and genetic study of 261 patients with breast cancer (BC) was carried out in Kiev region. It was demonstrated that the multifactorial origin of BC was of first importance in this population. The share of genetic component in the susceptibility to BC comprise 55.68 +/- 2.44%. Risk of the origin of malignant tumors in progeny was calculated.