"Dual Pandemics": Intersecting Influences of Anti-Black Racism and the COVID-19 Pandemic on the Mental Health of Black Youth.

BACKGROUND: The intersection of the COVID-19 pandemic with systemic anti-Black racism in the form of police violence and the subsequent Black Lives Matter movement has created an especially critical juncture to examine the mental health of Black youth. PURPOSE: The purpose of this study was to understand the intersecting impacts of anti-Black racism and the COVID-19 pandemic on the mental health of Black youth. METHODS: A youth-engaged research approach and intersectionality framework were utilized. Semi-structured interviews with Black youth across Canada (ages 16 to 30, n = 48) were conducted online via Zoom and analyzed using thematic analysis. Fourteen Black youth were hired to form a Black youth advisory committee, who guided the research process. RESULTS: The "dual pandemics" of the COVID-19 pandemic alongside highly publicized incidents of racism and the subsequent Black Lives Matter movement negatively impacted participants' mental health. Four main themes emerged: (1) ongoing exposure to acts of anti-Black racism (2) compounding effect of racism on mental health; (3) high stress levels and fear; and (4) anger and emotional fatigue from lack of shared, long-term solutions. CONCLUSION: The simultaneous occurrence of the COVID-19 pandemic and instances of systemic anti-Black racism in the form of police violence presented "dual pandemics" for the Black community, profoundly impacting the mental health of Black youth and adding urgency and impetus to its prioritization. Results of this study indicate that it is critical to explore each event individually as well as the combined impact on the mental health of Black youth, particularly from a racial perspective.

Impacts of Gum Arabic and Polyvinylpyrrolidone (PVP) with Salicylic Acid on Peach Fruit (Prunus persica) Shelf Life.

Peaches are grown in many Egyptian orchards for local and global fresh market sales. The interior fruit tissue breakdown (IFTB), often resulting in decayed peaches, is a severe problem during marketing. Therefore, to minimize FTB of peaches, in this study, gum arabic (GA) and polyvinylpyrrolidone (PVP) were mixed with different concentrations of salicylic acid (SA) (0, 1, and 2 mM) and were applied as edible coating to extend the shelf life of peach fruits. Mature peaches were selected and harvested when peaches reached total soluble solid content (SSC: 8.5%) and fruit firmness of about 47 N. Fruits were coated and stored at room temperature (26 ± 1 °C and air humidity 51 ± 1%) for 10 days during two seasons: 2020 and 2021. Fruit coated with GA/PVP-SA 2 mM showed a significant (p < 0.05) inhibition in degrading enzyme activities (CWDEs), such as lipoxygenase (LOX), cellulase (CEL), and pectinase (PT), compared to uncoated and coated fruits during the shelf-life period. Hence, cell wall compartments were maintained. Consequently, there was a reduction in browning symptoms in fruits by inhibiting polyphenol oxidase (PPO) and phenylalanine ammonia-lyase (PAL) activities. Thus, the fruit skin browning index showed almost no symptoms. The lipid peroxidation process and ionic permeability declined as well. The result suggests that, by applying GA/PVP-SA 2 mM as an edible coating, fruit tissue breakdown can be minimized, and the shelf life of peach can be extended up to 10 days without symptoms of tissue breakdown.

Successful oral treatment of third cranial nerve palsy and optic neuritis from neglected herpes zoster in an immunocompetent patient.

PURPOSE: Herpes zoster (HZ) is an acute viral eruption caused by the reactivation of varicella zoster virus (VZV), a herpes virus causing chicken pox in children. We aimed to report a 3-month neglected case of acute herpes zoster-induced third nerve palsy and optic neuritis, followed by a late-onset keratouveitis in an immunocompetent young adult. OBSERVATIONS: A 36-year old immunocompetent Egyptian male patient presented with 3-month complaints of blurred vision and drooping of his left upper eyelid that appeared 4 days after a herpetic rash. He had been diagnosed with herpes zoster ophthalmicus (HZO) of the left eye. However, he had not received any systemic antiviral treatment. The patient had an abnormal head posture with post-eruptive scars on the left forehead and the nose tip. Examination revealed weakness of elevation and adduction, partial ptosis, and mid-dilated non-reactive pupil in the left eye. A relative afferent pupillary defect (RAPD) was present in the affected eye. His blood sugar and blood pressure were within normal limits. Contrast magnetic resonance imaging (MRI) showed no space-occupying lesion. However, there were enhancement and enlargement of the left optic nerve on T1-weighted images, denoting optic neuritis. A diagnosis of acute left third nerve palsy with pupil involvement and optic neuritis secondary to HZO was made. Despite late treatment with oral acyclovir and prednisolone, the patient recovered. One and a half months later, he developed a late-onset keratouveitis about 8 months after the rash onset. After the resolution of the episode, oral acyclovir was continued at a prophylactic dose (400 mg BID). CONCLUSIONS AND IMPORTANCE: HZ is a rare cause of third nerve palsy with pupil involvement and optic neuritis. Oral acyclovir and steroids were effective in the delayed treatment in this case. Abnormal optic nerve enhancement on MRI 3 months after the appearance of vesicular rash may suggest chronic HZ activity. Concurrent optic neuritis and third cranial nerve palsy in the absence of other signs of orbital apex syndrome can be seen in cases of HZO. Regular follow-up of patients with HZ is important for detecting recurrence and initiating prompt treatment.

Topological variability and sex differences in fingerprint ridge density in a sample of the Sudanese population.

Fingerprints are important biometric variables that show manifold utilities in human biology, human morphology, anthropology, and genetics. Their role in forensics as a legally admissible tool of identification is well recognized and is based on their stability following full development, individualistic characteristics, easy classification of their patterns, and uniqueness. Nevertheless, fingerprint ridge density and its variability have not been previously studied in the Sudanese population. Hence, this study was conducted to analyze the topological variability in epidermal ridge density and to assess the possibility of its application in determining sex of Sudanese Arabs. The data used for this study were prints of all 10 fingers of 200 Sudanese Arab individuals (100 men and 100 women) aged between 18 and 28 years. Fingerprint ridge density was assessed for three different areas (radial, ulnar and proximal) for all 10 fingers of each subject. Significant variability was found between the areas (p < 0.01). Women showed significantly higher ridge density in the three areas for all and each fingers. Men and women showed similar patterns of densities with distal areas being denser than proximal ones. Side asymmetry was more evident in distal areas. Ridge density thresholds for discrimination of sexes were developed. Hence, fingerprints found in forensic examinations/crime scenes can be useful to determine sex of Sudanese individuals based on fingerprint ridge density; furthermore, ridge density can be considered a morphological trait for individual variation in forensic anthropology.

Helicobacter pylori infection and the onset of type 1 diabetes mellitus in Sudanese children.

Type 1 diabetes mellitus (T1DM) is a chronic T cell mediated autoimmune disease that results in destruction of pancreatic islet cells. Helicobacter pylori (HP) was recently thought to be a triggering factor for T1DM. This is a prospective case control study at Gaafar Ibnauf Children's Hospital and three other diabetic clinics in Khartoum, during the period January-September 2012. Ninety newly diagnosed T1DM children and a similar number of a control group were compared. Assessment of HP specific serum immunoglobulin was performed using Eliza test. There were 40(44.4%) female and 50(55.6%) male diabetic children. Diabetic children tested positive for HP constituted 56/90 (62.2%) compared to 59/90 (65.6%) from the control group. Diabetic children aged 11-18 years represented 46 (51%), 32/46 (57%) of them were seropositive for HP. A similar number of the same age in control group 30/46 (50.8%) were seropositive. Of 41newly diagnosed diabetic children (44.4%) of newly who complained of symptoms, 30 (53.6%) were seropositive for HP compared to 34 (37.7%) among the healthy children, out of whom 24 (40.7%) tested positive for HP. Diabetic children with moderate anemia were 35 (45.5%) compared to 54 (60.0%) in the control group. Seropositive children for HP in the 2 groups were, respectively, 20(40.8%) and 38(64.4%). Those with a poor family background were 28 (56%), 20 (40.0%) tested positive for HP, compared to 38 (64.4%), of whom 20 (64.5%) were seropositive in the controls. In conclusion, HP infection does not seem to play a role in triggering T1DM in children.