1.
J Org Chem
; 77(6): 2978-82, 2012 Mar 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22372387
RESUMO
Intramolecular hydroarylation of 4-benzofuranyl alkynoates using Pd(OAc)(2) as catalyst took place selectively and efficiently, giving angular furocoumarin derivatives in high yields. The parent angelicin was obtained in 80% yield by this method. The starting 4-benzofuranyl alkynoates were easily accessible from readily available 4-hydroxybenzofurans and alkynoic acids.