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1.
Artigo em Russo | MEDLINE | ID: mdl-21913399

RESUMO

AIM: Evaluation of antimicrobial activity of L-cysteine silver gel against various species of pathogenic and opportunistic microorganisms. MATERIALS AND METHODS: Antibacterial activity of L-cysteine silvergel with silver concentration from 1.28 x 10(-3) to 3.75 x10(-3) mole/l was studied by using agar diffusion test. Reparation processes were determined experimentally in 102 male Wistar rats (150 g) by forming under ether anesthesia a 225 mm2 skin wound on the back surface of the body and by introducing virulent strain Staphylococcus aureus 236 24-hour suspension (10(6) CFU/ml) inside the wound. The rat wounds were treated with L-cysteine silver gel once per day for one week and proliferation processes were studied on day 7, 14 and 21. RESULTS: Antibacterial activity of L-cysteine silver gel was detected against test strains: S. aureus ATCC 25923; Bacillus subtilis 537; Escherichia coli ATCC 25922; Shigella sonnei 1908; Pseudomonas aeruginosa ATCC 27853; Salmonella typhimurium 5715 and Candida albicans ATCC 885-653. Mean period of wound healing was reduced by 3 days when L-cysteine silver gel was used, index of healing acceleration was approximately 20%. CONCLUSION: L-cysteine silver gel has antibacterial and wound healing properties, it can be used for the creation of new medical preparations.


Assuntos
Antibacterianos/farmacologia , Cisteína/farmacologia , Nanoestruturas , Prata/farmacologia , Infecção dos Ferimentos/microbiologia , Animais , Candida albicans/efeitos dos fármacos , Escherichia coli/efeitos dos fármacos , Géis , Masculino , Testes de Sensibilidade Microbiana , Pseudomonas aeruginosa/efeitos dos fármacos , Ratos , Shigella sonnei/efeitos dos fármacos , Staphylococcus aureus/efeitos dos fármacos , Cicatrização/efeitos dos fármacos
2.
Radiat Prot Dosimetry ; 119(1-4): 41-4, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16644999

RESUMO

The present report deals with the experimental observations of the thermally stimulated migration of charge carriers from trapping centres responsible for the main thermoluminescence (TL) peak at 450 K to a deep trap and, also, the optically stimulated transport of carriers from the deep trap to the main trap, which gives rise to the phototransferred TL at 450 K, in anion-defective alpha-Al2O3 crystals. The obtained results provide an experimental proof to the adequacy of the assumptions made in the model of the mutual interaction of the main and deep traps in the crystals under study.


Assuntos
Óxido de Alumínio/efeitos da radiação , Modelos Químicos , Dosimetria Termoluminescente/instrumentação , Simulação por Computador , Desenho Assistido por Computador , Relação Dose-Resposta à Radiação , Desenho de Equipamento , Análise de Falha de Equipamento , Raios gama , Temperatura Alta , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Dosimetria Termoluminescente/métodos
3.
Klin Lab Diagn ; (3): 16-21, 2004 Mar.
Artigo em Russo | MEDLINE | ID: mdl-15137198

RESUMO

The passing and optic-density parameters registered by a photometric device were estimated, on the basis of a simple modeled system, with respect to the ratio between the absorption band width and the heterogeneous radiation degree. The impacts of heterogeneous radiation on the validity of the Bueguer'-Lambert's-Baire's law were elucidated.


Assuntos
Espectrofotometria/métodos , Algoritmos , Espectrofotometria/instrumentação , Espectrofotometria Infravermelho/instrumentação , Espectrofotometria Infravermelho/métodos , Espectrofotometria Ultravioleta/instrumentação , Espectrofotometria Ultravioleta/métodos
4.
Klin Lab Diagn ; (2): 6-11, 2002 Feb.
Artigo em Russo | MEDLINE | ID: mdl-11899538

RESUMO

The potentialities of photometry in the ultraviolet, visible, and infrared spectra are compared. Errors associated with neglect of the Booger-Lambert-Ber law, nonmonochromic light, inconstant length of optic route, and non-optimal choice of optic density range are analyzed.


Assuntos
Técnicas de Laboratório Clínico , Espectrofotometria/métodos , Espectroscopia de Luz Próxima ao Infravermelho , Humanos , Espectrofotometria Ultravioleta
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