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Transplant Proc ; 47(5): 1429-32, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26093735

RESUMO

Kidney transplantation (KT) is the best available therapy for patients with end-stage renal disease. Infectious complications are a common cause of morbidity and mortality. In this study, we evaluated the risk factors and outcomes of infectious complications in the first year after transplantation. This is a retrospective and observational study of kidney transplant recipients at Ankara University's Ibni Sina Hospital between January 2009 and August 2013. A total of 206 kidney transplant recipients were evaluated. In 129 patients, 298 infectious episodes occurred: 55 (26.7%) had 1; 33 (16%) 2; 19 (9.2%) 3; 7 (3.4%) 4; and 15 (7.3%) had 5 or more infectious episodes. The most common bacterial infection was urinary tract infection (128, 42.9%). Only 4 urinary tract infection episodes (3.1%) were associated with bacteriemia. Seventeen patients (5.7%) had bacteremia. Viral infections after transplantation were CMV infection (10.1%), BK virus infection (5.7%), and zona zoster (1.1%). Deceased donor kidney transplantation was the independent risk factor. Mean follow-up period was 66 months and was the same for the patients with and without infections. There was no significant difference in 5-year survival and creatinine levels at the last follow-up (logrank P = .409). Infections are the second most common cause of mortality in KT patients. The successful treatment of these complications and effective prophylaxis may decrease these complications.


Assuntos
Doenças Transmissíveis/mortalidade , Falência Renal Crônica/complicações , Transplante de Rim/mortalidade , Adulto , Vírus BK , Bacteriemia/etiologia , Infecções Bacterianas/etiologia , Doenças Transmissíveis/etiologia , Creatinina/sangue , Infecções por Citomegalovirus/virologia , Feminino , Seguimentos , Herpes Zoster , Humanos , Falência Renal Crônica/mortalidade , Masculino , Pessoa de Meia-Idade , Infecções por Polyomavirus/virologia , Estudos Retrospectivos , Fatores de Risco , Análise de Sobrevida , Infecções Tumorais por Vírus/virologia , Infecções Urinárias/etiologia
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