Cross cultural analysis of factors associated with age at natural menopause among Latin-American immigrants to Madrid and their Spanish neighbors.

OBJECTIVES: In this study, age at menopause was examined in relation to demographic and life style factors among Latin-American immigrants to Madrid and their Spanish counterparts. METHODS: Respondents were drawn from the Decisions at Menopause Study (2002-2003) and from a recent sample of Latin-American immigrants to Madrid (2010-2011). The final sample included 484 women after excluding women with induced menopause and use of HT. Probit analyses and Cox proportional hazard models were used to estimate median age at menopause and to identify factors associated with an early age at menopause. RESULTS: Median estimated age at natural menopause was 52.0 years (51.2-53.0) for Spanish women and 50.5 years (49.9-51.2) for Latin-American women. Immigrant women were more likely to reach menopause at an earlier age after controlling for confounding factors. Nulliparity and lower levels of education were associated with an earlier age at menopause. A higher body mass index was associated with a later age at menopause in the Spanish model. Among the Latin-American sample, women from the Dominican Republic and women who underwent menopause before migrating were more likely to reach menopause at an earlier age. CONCLUSIONS: The results reported here demonstrate that early life events, including place of birth, and later life events, such as timing of migration, were associated with age at menopause. This study highlights the importance of taking into account differences in the age of onset of menopause in the multicultural population of Madrid when considering the health of women at midlife and beyond.

Cross-cultural analysis of determinants of hot flashes and night sweats: Latin-American immigrants to Madrid and their Spanish neighbors.

OBJECTIVE: This study applies a biocultural perspective to better understand the determinants of hot flashes and night sweats within immigrant and local populations in Madrid, Spain. METHODS: A combined sample of 575 women from Madrid, aged 45 to 55 years, was drawn from two studies. The Spanish sample (n = 274) participated in The Decisions At Menopause Study in 2000-2002. The Latin-American sample (n = 301) was drawn from immigrants to Madrid in 2010-2011. χ(2) analyses and logistic regression models were carried out on the combined sample, controlling for origin of provenance. RESULTS: Forty-four percent of women reported hot flashes, 36% reported night sweats, and 26% reported both symptoms. Compared with Spanish women, Latin-American women were less likely to report hot flashes (odds ratio, 0.7; 95% CI, 0.4-0.9), after demographic variables and menopause status were controlled for. The same was not found for night sweats and for both symptoms combined. Determinants of hot flashes differed from determinants of night sweats. CONCLUSIONS: Because their determinants differ, hot flashes and night sweats should be queried and analyzed separately. Latin-American women are less likely to report hot flashes, but not night sweats or both symptoms combined. More research is needed to clarify the differences in reported hot flashes, as the lesser reporting among immigrants could have been a cultural phenomenon rather than a biological phenomenon.