RESUMO
BACKGROUND: There are no large reported series determining the Covid-19 cancer patient's characteristics. We determine whether differences exist in cumulative incidence and mortality of Covid-19 infection between cancer patients and general population in Madrid. MATERIAL AND METHODS: We reviewed 1069 medical records of all cancer patients admitted at Oncology department between Feb 1 and April 7, 2020. We described Covid-19 cumulative incidence, treatment outcome, mortality, and associated risk factors. RESULTS: We detected 45/1069 Covid-19 diagnoses in cancer patients vs 42,450/6,662,000 in total population (p < 0.00001). Mortality rate: 19/45 cancer patients vs 5586/42,450 (p = 0.0001). Mortality was associated with older median age, adjusted by staging and histology (74 vs 63.5 years old, OR 1.06, p = 0.03). Patients who combined hydroxychloroquine and azithromycin presented 3/18 deaths, regardless of age, staging, histology, cancer treatment and comorbidities (OR 0.02, p = 0.03). CONCLUSION: Cancer patients are vulnerable to Covid-19 with an increase in complications. Combined hydroxychloroquine and azithromycin is presented as a good treatment option.
Assuntos
Infecções por Coronavirus/complicações , Infecções por Coronavirus/mortalidade , Neoplasias/complicações , Neoplasias/epidemiologia , Pneumonia Viral/complicações , Pneumonia Viral/mortalidade , Idoso , Azitromicina/uso terapêutico , Betacoronavirus/isolamento & purificação , COVID-19 , Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/tratamento farmacológico , Combinação de Medicamentos , Feminino , Humanos , Hidroxicloroquina/uso terapêutico , Incidência , Masculino , Pessoa de Meia-Idade , Neoplasias/patologia , Pandemias , Pneumonia Viral/diagnóstico , Pneumonia Viral/tratamento farmacológico , Fatores de Risco , SARS-CoV-2 , Espanha/epidemiologia , Resultado do TratamentoRESUMO
A population of the conch Strombus gigas was sampled in 109 transects (100 x 10 m each) for an area of 109000 m2 (eight surveys in 1998 and six in 1999) in Yucatan, Mexico; S. gigas was the most abundant conch species (97% of individuals) and ocurred at depths of 0.5-18 m. Mean density was 0.0084 individuals/m2 (Standard deviation SD=0.0138, n=1910). Maximum density (0.015 individuals/m2) was at 0.5-2 m and minimal (0.001 individuals/m2) at 16-18 m. Shell length was 120-290 mm (mena=211.6, SD=26, n=1136). Shell lip thickness, measured only in adults, was 1-28 mm (mean=8.7, SD=7.5, n=1136).
Assuntos
Animais , Caramujos , Caramujos/anatomia & histologia , Caramujos/classificação , México , Densidade Demográfica , Dinâmica Populacional , TemperaturaRESUMO
A population of the conch Strombus gigas was sampled in 109 transects (100 x 10 m each) for an area of 109000 m2 (eight surveys in 1998 and six in 1999) in Yucatan, Mexico; S. gigas was the most abundant conch species (97% of individuals) and ocurred at depths of 0.5-18 m. Mean density was 0.0084 individuals/m2 (Standard deviation SD=0.0138, n=1910). Maximum density (0.015 individuals/m2) was at 0.5-2 m and minimal (0.001 individuals/m2) at 16-18 m. Shell length was 120-290 mm (mena=211.6, SD=26, n=1136). Shell lip thickness, measured only in adults, was 1-28 mm (mean=8.7, SD=7.5, n=1136).