Total synthesis of naturally occurring abietane diterpenoids via a late-stage Fe(iii)-bTAML catalysed Csp3-H functionalization.

The synthesis of diverse trans-fused decalins, including the abietane diterpenoids scaffold, using an efficient selective oxidation strategy is described. The abietane core was demonstrated to be a versatile scaffold that can be site-selectively functionalized. The utility of this novel oxidation strategy was showcased in a concise total synthesis of six abietane congeners.

Electrochemical Regioselective C(sp2)-H Selenylation and Sulfenylation of Substituted 2-Amino-1,4-naphthoquinones.

A straightforward and efficient electrochemical method for regioselective C(sp2)-H selenylation and sulfenylation of substituted 2-amino-1,4-naphthoquinones has been unearthed. This oxidative cross-coupling reaction avoids using transition metal catalysts, oxidants, and high temperatures. The other notable advantages of this protocol are the tolerance of diverse functional groups, mild reaction conditions at ambient temperature, energy efficiency, good to excellent yields, short reaction times (in minutes), gram-scale applicability, and eco-friendliness.