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8.
Radiobiologiia ; 24(4): 554-5, 1984.
Artigo em Russo | MEDLINE | ID: mdl-6473734

RESUMO

In experiments on 80 Wistar male rats their motor activity was studied using "Optovarimex" device which permitted to register the position of animals in space. The rats were subjected to total-body gamma-irradiation with doses of 6.5, 13, 50 and 100 Gy. The motor activity was studied 1, 24, 72 and 96 h following irradiation. Inhibition of the motor activity of animals was shown to depend upon radiation dose.


Assuntos
Atividade Motora/efeitos da radiação , Animais , Relação Dose-Resposta à Radiação , Raios gama , Masculino , Ratos , Ratos Endogâmicos , Fatores de Tempo
12.
Kardiologiia ; 16(5): 94-9, 1976 May.
Artigo em Russo | MEDLINE | ID: mdl-181629

RESUMO

The activity of the respiratory enzymes of myocardial mitochondria--succinatedehydrogenase and cytochromixidase--was studied in experimentally induced aortic stenosis and after its elimination in 98 mongrel dogs. The observation period of stenosis was 1, 15, 30 and 60 days, and after its elimination--1, 7, 15 and 30 days. The activity of the enzymes in question was found to grow after the production of aortic stenosis. The highest level of their enzymatic activity was observed on the 15th day after the induction of stenosis. By the 30th and 60th day the enzymatic activity underwent some decrease, although it persisted on a level above the initial. The activity of succinatedehydrogenase fell sharper. After the elimination of the stenosis the activity of both enzymes decreased, and by the 7th day it was below the initial level. By the 15th day after the removal of the ligature from the aorta the activity of both enzymes corresponded to the initial values and did not change further till the end of the 1st month. The dynamics of the activity of succinatedehydrogenase and cytochromixidase after an experimentally induced aortic stenosis and its subsequent elimination seems to depend on the nature of the changes in the function of the heart muscle performed under such experimental pathology, and on the degree of coronary flow enhancement.


Assuntos
Estenose da Valva Aórtica , Mitocôndrias Musculares/enzimologia , Miocárdio/patologia , Animais , Estenose da Valva Aórtica/enzimologia , Estenose da Valva Aórtica/cirurgia , Cães , Complexo IV da Cadeia de Transporte de Elétrons/metabolismo , Succinato Desidrogenase/metabolismo
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