RESUMO
Bisphosphonates inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis,multiple myeloma and metastases associated with breast or prostate cancer. At present, there is no effectivetreatment for bisphosphonate induced osteonecrosis, so prevention is extremely important. Since quality oflife deteriorates for those suffering osteonecrosis, maximum precautions should be taken with patients at risk, andespecially whenever oral surgery, including dental implant placement, is contemplated. Dentists and oral or maxillofacialsurgeons must keep up to date with the latest approaches to prevention, particularly when treating patientswho are presently taking, or who will be taking bisphosphonates and are also candidates for dental implants (AU)
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Assuntos
Humanos , Difosfonatos/efeitos adversos , Implantes Dentários , Difosfonatos/administração & dosagem , Osteonecrose/induzido quimicamente , Osteonecrose/prevenção & controle , Administração Oral , Doenças Maxilomandibulares/induzido quimicamente , Doenças Maxilomandibulares/prevenção & controleRESUMO
Bisphosphonates inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis, multiple myeloma and metastases associated with breast or prostate cancer. At present, there is no effective treatment for bisphosphonate induced osteonecrosis, so prevention is extremely important. Since quality of life deteriorates for those suffering osteonecrosis, maximum precautions should be taken with patients at risk, and especially whenever oral surgery, including dental implant placement, is contemplated. Dentists and oral or maxillofacial surgeons must keep up to date with the latest approaches to prevention, particularly when treating patients who are presently taking, or who will be taking bisphosphonates and are also candidates for dental implants.