Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Surg Neurol ; 37(6): 477-81, 1992 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-1595054

RESUMO

Schizencephaly is characterized by unilateral or bilateral cerebral clefts associated with neurologic deficits and epilepsy. Most commonly schizencephaly is attributed to abnormal neuronal migration, and these malformations are well visualized by current neuroimaging techniques. This report describes a patient with unilateral schizencephaly and poorly controlled complex partial seizures who was found to have a temporal lobe seizure focus; anterior temporal lobectomy produced nearly complete control of the seizures. Despite the extensive malformation, relatively restricted resection was of significant benefit. The principles of seizure focus localization and resection are applicable to the management of patients with schizencephaly.


Assuntos
Encéfalo/anormalidades , Epilepsia/cirurgia , Lobo Temporal/cirurgia , Adulto , Paralisia Cerebral/complicações , Epilepsia/etiologia , Epilepsia/patologia , Lateralidade Funcional , Humanos , Imageamento por Ressonância Magnética , Masculino , Lobo Temporal/patologia
2.
Am J Med ; 81(4): 734-40, 1986 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-3766605

RESUMO

Since its first description, fewer than 150 cases of benign hypergammaglobulinemic purpura of Waldeström have been reported. There is a preponderance of females with this disorder, which is characterized by long-standing purpuric vasculitic lesions usually in the lower extremities, increased sedimentation rate, anemia, leukopenia, and hyperglobulinemia with a normal clotting process. Numerous associations have been shown between this and other systemic disorders such as Sjögren's syndrome, systemic lupus erythematosus, a rheumatoid arthritis. A 40-year-old woman is described who had an 18-year history of recurrent purpura and increased IgG levels. Skin biopsy showed acute vasculitis, and immunofluorescent study revealed fibrinogen precipitation and C3 deposition. Serologic evaluation demonstrated the presence of rheumatoid factor and antinuclear antibodies (1:80). Raji assay showed increased circulating immune complexes, and the T cell subsets were normal. The purpura was associated with symptoms and physical findings of Sjögren's syndrome. On the basis of serologic and skin biopsy findings, an autoimmune origin of the disease is postulated.


Assuntos
Doenças Autoimunes/fisiopatologia , Púrpura Hiperglobulinêmica/complicações , Síndrome de Sjogren/complicações , Adulto , Doenças Autoimunes/tratamento farmacológico , Clorambucila/uso terapêutico , Feminino , Humanos , Púrpura Hiperglobulinêmica/tratamento farmacológico , Púrpura Hiperglobulinêmica/imunologia , Púrpura Hiperglobulinêmica/fisiopatologia , Síndrome de Sjogren/imunologia , Síndrome de Sjogren/fisiopatologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA