[Radical prostatectomy in patients with history of transurethral resection of the prostate]. / Prostatectomía radical en pacientes con antecedentes de RTU próstata.

OBJECTIVES: To perform a retrospective evaluation of surgical complications and morbidity in patients undergoing radical retropubic prostatectomy (RRP) as elective treatment for organ-confined prostate cancer in our center with previous transurethral resection of the prostate (TURP). METHODS: Between 1980-2004 we performed 59 radical prostatectomies in patients with previous TURP. We analyze the morbidity and mortality of the RRP, its functional outcomes, and the accordance between clinical and pathological stage. RESULTS: Mean time between TURP and RRP was 16 months. Mean patient age at the time of diagnosis was 63 years. Clinical stage: 16 T1a, 18T1b, 20T1c, 3T2a, 2T2b. Average surgical time was 180 minutes. Intraoperative events: technical difficulties in the dissection of the gland 57%, bladder neck preservation 27%, neuro vascular bundles preservation 3.39%, ureter ligation 1.69%, rectal laceration 1.69, urethrorrhagia 1.69%, urinary leak 5%, and blood transfusions 11.8%. Postoperative complications: urinary tract infection 10.17%, wound infection 10.17%, pelvic hematoma 5.08%, deep vein thrombosis 1.69%, and one sudden death of unknown cause one month after surgery. Pathologic report: 49pT2b, 8 pT3 and 2pT4. Late complications: erectile dysfunction 85.7%, vesicourethral anastomosis stenosis 10.3%, and complete urinary incontinence 3%. CONCLUSIONS: Radical retropubic prostatectomy in patients with previous TURP is technically more difficult and has comparable outcomes to RRP patients without previous TURP.

Prostatectomíia radical en pacientes con antecedentes de RTU de próstata / Radical prostatectomy in patients with history of transurethral resection of the prostate

OBJETIVO: Nuestro objetivo ha sido realizar una valoración retrospectiva en nuestro centro de las complicaciones quirúrgicas y de morbilidad en pacientes intervenidos de prostatectomía radical retropúbica como tratamiento electivo del cáncer de próstata órgano confinado, con antecedentes de resección transuretral de próstata (RTUp). MÉTODOS: Entre 1980-2004 hemos realizado 59 prostatectomías radicales en pacientes con RTUp previa. Se analiza morbimortalidad de la PRR, resultados funcionales y concordancia entre estadiaje clínico y patológico. RESULTADOS: El tiempo medio transcurrido entre la RTUp y la prostatectomía radical 16 meses. Edad media en el momento de diagnóstico de adenocarcinoma de próstata 63 años. Estadiaje clínico: 16T1a, 18T1b, 20T1c, 3 T2a, 2 T2b. La media de tiempo quirúrgico de la PRR 180 minutos. Incidencias intraoperatorias: Dificultades técnicas en la disección de la glándula 57%, preservación del cuello vesical 27%, preservación de bandeletas neurovasculares 3.39%, ligadura de uréter 1.69%, lesión rectal 1.69%, uretrorragia 1.69%, fístula urinaria 5% y el 11.8% requirió transfusión. Como complicaciones postoperatorias: ITU 10.17%, infección de la herida 10.17%, hematoma pélvico 5.08%, TVP 1.69% y un paciente falleció súbitamente al mes de la cirugía por causa no filiada. Estadío patológico: 49pT2b, 8pT3 y 2pT4. Como complicaciones tardías: Disfunción eréctil 85.7%, estenosis de la anastomosis 10.3% e incontinencia urinaria total 3%. CONCLUSIÓN: La PRR en pacientes con RTUp previa es técnicamente más dificultosa con resultados comparables con los pacientes sin cirugía prostática previa

OBJECTIVES: To perform a retrospective evaluation of surgical complications and morbidity in patients undergoing radical retropubic prostatectomy (RRP) as elective treatment for organ-confined prostate cancer in our center with previous transurethral resection of the prostate (TURP). METHODS: Between 1980-2004 we performed 59 radical prostatectomies in patients with previous TURP. We analyze the morbidity and mortality of the RRP, its functional outcomes, and the accordance between clinical and pathological stage. RESULTS: Mean time between TURP and RRP was 16 months. Mean patient age at the time of diagnosis was 63 years. Clinical stage: 16 T1a,18T1b,20T1c, 3T2a,2T2b. Average surgical time was 180 minutes. Intraoperative events: technical difficulties in the dissection of the gland 57%, bladder neck preservation 27%, neuro vascular bundles preservation 3.39%, ureter ligation 1.69%, rectal laceration 1.69, urethrorrhagia 1.69%, urinary leak 5%, and blood transfusions 11.8%. Post-operative complications: urinary tract infection 10.17%, wound infection 10.17%, pelvic hematoma 5.08%, deep vein thrombosis 1.69%, and one sudden death of unknown cause one month after surgery . Pathologic report: 49pT2b, 8 pT3 and 2pT4. Late complications: erectile dysfunction 85.7%, vesicourethral anastomosis stenosis 10.3%, and complete urinary incontinence 3%. CONCLUSIONS: Radical retropubic prostatectomy in patients with previous TURP is technically more difficult and has comparable outcomes to RRP patients without previous TURP