Association of mandible anatomy with age, gender, and dental status: a radiographic study.

Introduction. Gonial angle and antegonial region are important landmarks in mandible which is influenced by gender, age, and dental status. The objective of this study was to evaluate the gonial angle, antegonial angle, and antegonial depth and to investigate their relationship to gender, age group, and dental status. Materials and Methods. A total of 1060 panoramic radiographs were evaluated: the dentulous group, 854 subjects and the edentulous group, 206 subjects. The patients were grouped into six age groups of 10-years each. Gonial angle, antegonial angle, and antegonial depth were measured from panoramic radiographs. Results and Discussion. Corelation of age with gonial angle, antegonial angle and antegonial depth was not significant. Significant difference in mandibular angle was found between males and females. Males had significantly smaller antegonial angle and greater antegonial depth than females. Significant difference was found for gonial angle, antegonial angle, and antegonial depth between right and left sides of mandible. Conclusion. Gonial angle, antegonial angle, and antegonial depth can be implicated as a forensic tool for gender determination but not suitable for age determination.

Estimation of serum malondialdehyde in oral cancer and precancer and its association with healthy individuals, gender, alcohol, and tobacco abuse.

BACKGROUND: Tobacco and alcohol induces generation of free radicals and reactive oxygen species, which are responsible for high rate of lipid peroxidation. Malondialdehyde is the most widely used marker of lipid peroxidation. The aim of the study was to estimate serum malondialdehyde level in oral precancer, oral cancer, and normal individuals. MATERIALS AND METHODS: In this study serum malondialdehyde was measured according to the method of Ohkawa et al in 30 normal individuals and 30 patients each with histopathologically diagnosed oral precancer, and oral cancer. RESULTS: The mean serum malondialdehyde level in the control group was found to be 5.107 ± 2.32 ηmol/ml, whereas it was 9.33 ± 4.89 ηmol/ml and 14.34 ± 1.43 ηmol/ml in oral precancer and oral cancer, respectively. There was statistically significant increase in serum malondialdehyde levels in the oral precancer and oral cancer patients compared with the control group. CONCLUSION: Increased serum malondialdehyde in oral cancer and oral precancer would serve as a valuable marker for both preventive and clinical intervention, and may deserve further investigation for the early diagnosis, treatment, and prognosis.