Optic nerve disc veins inflammation (papillophlebitis) - case report.

Papillophlebitis is an uncommon disease in clinical practice. We would like to present a case of a 29-year-old patient with atypical orbital pain and flashings, presenting relative afferent pupillary defect and already typical of the disease entity: ophthalmoscopic picture of the fundus and big blind spot in perimetry. We present a complex and interdisciplinary diagnostic process that excludes general diseases such as hypertension, diabetes, coagulation disorders and neurological causes. We leave the only identifiable abnormality and potential source in the inflammatory process of periodontal inflammation and sinus jaw changes. We also describe the process of remitting the changes and finally a favorable end result of the primarily a very disturbing clinical picture that this disease may present.

The role of vitamin D in the pathogenesis of ocular diseases.

The prevalence of vitamin D deficiency in the American and European population is estimated to be extremely high. Although fewer people today su er from serious health problems related to calcium and phosphate metabolism resulting from vitamin D deficiency, there are more and more studies suggesting that calcitriol may play an important role in the pathogenesis of other diseases in virtually every body system. A growing body of research shows that through its ubiquitously expressed receptor, calcitriol displays potent anti-angiogenic an anti-inflammatory activity. This review summarizes recent discoveries regarding these non-classical effects of vitamin D and their clinical implications. Data collection focused on the prevention and treatment of ocular diseases as well as on the underlying mechanisms.

Outcome of the first year of treatment for exudative age-related macular degeneration under a treatment programme using aflibercept - own experience.

STUDY OBJECTIVE: Anatomic and functional (function improvement) outcome of the aflibercept treatment for exudative age-related macular degeneration was analysed a er the first year of treatment. MATERIAL AND METHODS: 62 patients treated with intravitreal aflibercept injections according to the adapted regimen. The treatment efficacy was understood as a reduction in oedema (and the central retinal thickness), with an increase in or stabilisation of the best corrected visual acuity. RESULTS: In nearly all patients, a reduction in the central retinal thickness was observed, with stabilisation of or improvement in the best corrected visual acuity. CONCLUSION: The aflibercept treatment for exudative age-related macular degeneration is a promising and efficient treatment method.