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2.
Anaesthesiologie ; 72(6): 433-444, 2023 06.
Artigo em Alemão | MEDLINE | ID: mdl-36930267

RESUMO

Currently, few robust data are available to provide estimates of the environmental footprint and in particular the CO2 emissions of medical devices; however, existing life cycle assessments largely indicate that reusable materials have more favorable emissions and environmental footprints compared to disposable items. Thus, the challenge for every anesthesiology department is to identify items that can be used as reusable products for ecological and other reasons.A prerequisite for the use of reusable items is hygienically correct reprocessing and packaging. Here, a distinction must be made between noncritical, semicritical and critical medical devices, depending on the type of use. In addition, a distinction must be made between categories A-C, depending on the complexity of the reprocessing.In this narrative review article common reusable items used in anesthesiology are categorized and a standardized decision algorithm for reprocessing routes is proposed. Special attention is also given to the packaging of medical devices, which can contribute to the ecological footprint to a relevant extent.This article further explains the framework under which reprocessing can take place and analyzes the current state of knowledge on the life cycle assessment of reprocessing reusable devices.This requires the special commitment of clinically active anesthesiologists to include ecological aspects in the decision to use disposable or reusable items. In the medium term, comprehensible ecological key numbers should be provided on every medical device to make the ecological costs of the articles understandable in addition to the monetary costs.


Assuntos
Anestesiologia , Anestésicos , Dióxido de Carbono , Equipamentos Descartáveis , Custos e Análise de Custo
4.
Ann Surg ; 246(2): 192-200, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17667496

RESUMO

OBJECTIVE: To characterize the beneficial effects of perioperative systemic lidocaine on length of hospital stay, gastrointestinal motility, and the inflammatory response after colorectal surgery. SUMMARY BACKGROUND DATA: Surgery-induced stimulation of the inflammatory response plays a major role in the development of several postoperative disorders. Local anesthetics possess anti-inflammatory activity and are thought to positively affect patients' outcome after surgery. This double-blinded, randomized, and placebo-controlled trial aimed to evaluate beneficial effects of systemic lidocaine and to provide insights into underlying mechanisms. METHODS: Sixty patients undergoing colorectal surgery, not willing or unable to receive an epidural catheter, were randomly assigned to lidocaine or placebo treatment. Before induction of general anesthesia, an intravenous lidocaine bolus (1.5 mg/kg) was administered followed by a continuous lidocaine infusion (2 mg/min) until 4 hours postoperatively. Length of hospital stay, gastrointestinal motility, and pain scores were recorded and plasma levels or expression of pro- and anti-inflammatory mediators determined. RESULTS: Lidocaine significantly accelerated return of bowel function and shortened length of hospital stay by one day. No difference could be observed in daily pain ratings. Elevated plasma levels of IL-6, IL-8, complement C3a, and IL-1ra as well as expression of CD11b, L- and P-selectin, and platelet-leukocyte aggregates were significantly attenuated by systemic lidocaine. CONCLUSIONS: Perioperative intravenous lidocaine not only improved gastrointestinal motility but also shortened length of hospital stay significantly. Anti-inflammatory activity modulating the surgery-induced stress response may be one potential mechanism. Systemic lidocaine may thus provide a convenient and inexpensive approach to improve outcome for patients not suitable for epidural anesthesia.


Assuntos
Anestésicos Locais/administração & dosagem , Colectomia/métodos , Doenças do Colo/cirurgia , Tempo de Internação/tendências , Lidocaína/administração & dosagem , Cuidados Pré-Operatórios/métodos , Doenças Retais/cirurgia , Adolescente , Adulto , Idoso , Biomarcadores/sangue , Antígeno CD11b/biossíntese , Antígeno CD11b/sangue , Doenças do Colo/sangue , Doenças do Colo/fisiopatologia , Complemento C3a/biossíntese , Método Duplo-Cego , Ensaio de Imunoadsorção Enzimática , Feminino , Seguimentos , Motilidade Gastrointestinal/efeitos dos fármacos , Motilidade Gastrointestinal/fisiologia , Humanos , Infusões Intravenosas , Interleucinas/biossíntese , Interleucinas/sangue , Selectina L/biossíntese , Selectina L/sangue , Masculino , Pessoa de Meia-Idade , Selectina-P/biossíntese , Selectina-P/sangue , Complicações Pós-Operatórias/prevenção & controle , Prognóstico , Doenças Retais/sangue , Doenças Retais/fisiopatologia , Estudos Retrospectivos
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