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J Biomed Mater Res B Appl Biomater ; 96(2): 369-75, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21210518

RESUMO

In this work, we propose the use of shape-memory polymer as an anchoring system for a bladder sensor. The anchoring system was designed from a biomedical biodegradable water-based poly(ester-urethane) produced in an aqueous environment by using isophorone diisocyanate/hydrazine (hard segment) and poly(caprolactone diol)/2,2-bis (hydroxymethyl) propionic acid (soft segment) as the main reagents. Tensile strength and elongation-at-break deterioration upon degradation in synthetic urine were investigated. In-body shape recovery was simulated and measured in synthetic urine. Results indicated that shape recovery can occur at body temperature and expulsion of the sensor by the body along with urine may occur through the combined effect of urine hydrolytic attack and compression exerted by the bladder walls.


Assuntos
Materiais Biocompatíveis/uso terapêutico , Equipamentos para Diagnóstico , Impedância Elétrica/uso terapêutico , Poliuretanos/uso terapêutico , Bexiga Urinária/fisiologia , Desenho de Equipamento , Teste de Materiais , Modelos Biológicos , Temperatura , Urina
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