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1.
Phys Rev Lett ; 130(17): 173202, 2023 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-37172235

RESUMO

We report on the first demonstration of transport of a multispecies ion crystal through a junction in a rf Paul trap. The trap is a two-dimensional surface-electrode trap with an X junction and segmented control electrodes to which time-varying voltages are applied to control the shape and position of potential wells above the trap surface. We transport either a single ^{171}Yb^{+} ion or a crystal composed of a ^{138}Ba^{+} ion cotrapped with the ^{171}Yb^{+} ion to any port of the junction. We characterize the motional excitation by performing multiple round-trips through the junction and back to the initial well position without cooling. The final excitation is then measured using sideband asymmetry. For a single ^{171}Yb^{+} ion, transport with a 4 m/s average speed induces between 0.013±0.001 and 0.014±0.001 quanta of excitation per round-trip, depending on the exit port. For a Ba-Yb crystal, transport at the same speed induces between 0.013±0.001 and 0.030±0.002 quanta per round-trip of excitation to the in-phase axial mode. Excitation in the out-of-phase axial mode ranges from 0.005±0.001 to 0.021±0.001 quanta per round-trip.

3.
BMJ Nutr Prev Health ; 5(1): 118-133, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35814725

RESUMO

Pre-eclampsia affects 3%-5% of pregnant women worldwide and is associated with a range of adverse maternal and fetal outcomes, including maternal and/or fetal death. It particularly affects those with chronic hypertension, pregestational diabetes mellitus or a family history of pre-eclampsia. Other than early delivery of the fetus, there is no cure for pre-eclampsia. Since diet or dietary supplements may affect the risk, we have carried out an up-to-date, narrative literature review to assess the relationship between nutrition and pre-eclampsia. Several nutrients and dietary factors previously believed to be implicated in the risk of pre-eclampsia have now been shown to have no effect on risk; these include vitamins C and E, magnesium, salt, ω-3 long-chain polyunsaturated fatty acids (fish oils) and zinc. Body mass index is proportionally correlated with pre-eclampsia risk, therefore women should aim for a healthy pre-pregnancy body weight and avoid excessive gestational and interpregnancy weight gain. The association between the risk and progression of the pathophysiology of pre-eclampsia may explain the apparent benefit of dietary modifications resulting from increased consumption of fruits and vegetables (≥400 g/day), plant-based foods and vegetable oils and a limited intake of foods high in fat, sugar and salt. Consuming a high-fibre diet (25-30 g/day) may attenuate dyslipidaemia and reduce blood pressure and inflammation. Other key nutrients that may mitigate the risk include increased calcium intake, a daily multivitamin/mineral supplement and an adequate vitamin D status. For those with a low selenium intake (such as those living in Europe), fish/seafood intake could be increased to improve selenium intake or selenium could be supplemented in the recommended multivitamin/mineral supplement. Milk-based probiotics have also been found to be beneficial in pregnant women at risk. Our recommendations are summarised in a table of guidance for women at particular risk of developing pre-eclampsia.

4.
Eval Rev ; 43(6): 396-425, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31973597

RESUMO

The Nutrition Embedding Evaluation Programme (NEEP) was a global 4-year program (2013-2017) funded by the United Kingdom Department for International Development created to respond to gaps in the nutrition evidence base. The NEEP implementing agency-PATH-provided grants and evaluation technical assistance (ETA) to civil society organizations (CSOs) from 12 countries to conduct robust nutrition-related impact evaluations. The programmatic approach of having an intermediary agent to manage the funding and ETA mechanisms for nutrition impact evaluations is rare and therefore provides a unique opportunity to understand its effectiveness. Over the program duration, NEEP collected lessons learned that were analyzed and disaggregated into key themes considered critical for the completion of high-quality impact evaluations. From these lessons learned, NEEP provides an ETA program model that can be replicated or adapted to other international development sectors. This model highlights the key role of the three tiers (donor, ETA manager, and CSOs) in ensuring the best value for money and effective technical support for conducting impact evaluations and fostering the importance of knowledge uptake and evaluative culture for maximum knowledge diffusion. In this way, global research can be targeted to approaches that provide options to collaborate with the program implementers and contribute to a holistic evidence base to inform policy and programmatic decisions.


Assuntos
Dieta Saudável , Avaliação de Programas e Projetos de Saúde/métodos , Fortalecimento Institucional , Comportamento Cooperativo , Custo Compartilhado de Seguro , Análise Custo-Benefício , Promoção da Saúde , Humanos , Avaliação de Programas e Projetos de Saúde/economia , Reino Unido
5.
Science ; 360(6396): 1429-1434, 2018 06 29.
Artigo em Inglês | MEDLINE | ID: mdl-29954972

RESUMO

Topological order is often quantified in terms of Chern numbers, each of which classifies a topological singularity. Here, inspired by concepts from high-energy physics, we use quantum simulation based on the spin degrees of freedom of atomic Bose-Einstein condensates to characterize a singularity present in five-dimensional non-Abelian gauge theories-a Yang monopole. We quantify the monopole in terms of Chern numbers measured on enclosing manifolds: Whereas the well-known first Chern number vanishes, the second Chern number does not. By displacing the manifold, we induce and observe a topological transition, where the topology of the manifold changes to a trivial state.

6.
Public Health Nutr ; 20(7): 1286-1296, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28065195

RESUMO

The goals of the present targeted review on maternal and child overweight and obesity were to: (i) understand the current situation in low- and middle-income countries (LMIC) with regard to recent trends and context-specific risk factors; and (ii) building off this, identify entry points for leveraging existing undernutrition programmes to address overweight and obesity in LMIC. Trends reveal that overweight and obesity are a growing problem among women and children in LMIC; as in Ghana, Kenya, Niger, Sierra Leone, Tanzania and Zimbabwe, where the prevalence among urban women is approaching 50 %. Four promising entry points were identified: (i) the integration of overweight and obesity into national nutrition plans; (ii) food systems (integration of food and beverage marketing regulations into existing polices on the marketing of breast-milk substitutes and adoption of policies to promote healthy diets); (iii) education systems (integration of nutrition into school curricula with provision of high-quality foods through school feeding programmes); and (iv) health systems (counselling and social and behaviour change communication to improve maternal diet, appropriate gestational weight gain, and optimal infant and young child feeding practices). We conclude by presenting a step-by-step guide for programme officers and policy makers in LMIC with actionable objectives to address overweight and obesity.


Assuntos
Países em Desenvolvimento , Desnutrição/epidemiologia , Obesidade/epidemiologia , Sobrepeso/epidemiologia , África Subsaariana/epidemiologia , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Dieta , Feminino , Humanos , Lactente , Fenômenos Fisiológicos da Nutrição Materna , Mães , Política Nutricional , Estado Nutricional , Prevalência , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores de Risco , Aumento de Peso
7.
BMC Nutr ; 3: 26, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-32153808

RESUMO

BACKGROUND: When food is available, the main obstacle to access is usually economic: people may not be able to afford a nutritious diet, even if they know what foods to eat. The Cost of the Diet method and software was developed to apply linear programming to better understand the extent to which poverty may affect people's ability to meet their nutritional specifications. This paper describes the principles of the method; the mathematics underlying the linear programming; the parameters and assumptions on which the calculations are based; and then illustrates the output of the software using examples taken from assessments. RESULTS: The software contains five databases: the energy and nutrient content of foods; the energy and nutrient specifications of individuals; predefined groups of individuals in typical households; the portion sizes of foods; and currency conversion factors. Data are collected during a market survey to calculate the average cost of foods per 100 g while focus group discussions are used to assess local dietary habits and preferences. These data are presented to a linear programming solver within the software which selects the least expensive combination of local foods for four standard diets that meet specifications for: energy only; energy and macronutrients; energy, macronutrients and micronutrients; and energy, macronutrients and micronutrients but with constraints on the amounts per meal that are consistent with typical dietary habits. Most parameters in the software can be modified by users to examine the potential impact of a wide range of theoretical interventions. The output summarises for each diet the costs, quantity and proportion of energy and nutrient specifications provided by all the foods selected for a given individual or household by day, week, season and year. When the cost is expressed as a percentage of income, the affordability of the diet can be estimated. CONCLUSIONS: The Cost of the Diet method and software could be used to inform programme design and behaviour change communication in the fields of nutrition, food security, livelihoods and social protection as well as to influence policies and advocacy debates on the financial cost of meeting energy and nutrient specifications.

9.
Public Health Nutr ; 17(3): 689-99, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24103388

RESUMO

OBJECTIVE: There is a recognised need to strengthen capacity in the nutrition in emergencies sector and for greater clarity on the role of emergency nutritionists and the skills they require. Competency frameworks are an important tool for human resource development and have been developed for several other humanitarian sectors. We therefore developed a technical competency framework for practitioners in nutrition in emergencies. DESIGN: Existing competency frameworks were reviewed and interviews conducted to explore methods used in developing competency frameworks for other sectors. Competencies were identified through interviews with field experts, feedback from course trainees, academic course content and job specifications. Competencies were then categorised and behavioural indicators developed for each. The draft framework was then reviewed by members of the Global Nutrition Cluster and modified in an iterative process. SETTING: Global. SUBJECTS: Not applicable. RESULTS: A wide range of competencies were identified as essential for nutritionists working in emergencies, covering technical skills and general core competencies. The proposed framework contains twenty competency areas with 161 behavioural indicators categorised into three levels, corresponding to the requirements of progressively more senior roles. Many of the competencies are common across development and emergency nutrition. CONCLUSIONS: The proposed technical competency framework should prove to be a valuable tool in creating standards within the sector and promoting effective capacity strengthening and professionalisation. Continued research is needed to validate the framework, optimise methods for assessment, develop approaches to integrate it within the sector and measure its impact on performance.


Assuntos
Fortalecimento Institucional , Educação Baseada em Competências/métodos , Emergências , Nutricionistas/organização & administração , Competência Profissional , Pessoal Administrativo , Humanos , Entrevistas como Assunto , Administração em Saúde Pública , Pesquisa Qualitativa , Trabalho de Resgate/organização & administração , Reino Unido
10.
Proc Natl Acad Sci U S A ; 109(27): 10811-4, 2012 Jul 03.
Artigo em Inglês | MEDLINE | ID: mdl-22699494

RESUMO

Measurement techniques based upon the Hall effect are invaluable tools in condensed-matter physics. When an electric current flows perpendicular to a magnetic field, a Hall voltage develops in the direction transverse to both the current and the field. In semiconductors, this behavior is routinely used to measure the density and charge of the current carriers (electrons in conduction bands or holes in valence bands)--internal properties of the system that are not accessible from measurements of the conventional resistance. For strongly interacting electron systems, whose behavior can be very different from the free electron gas, the Hall effect's sensitivity to internal properties makes it a powerful tool; indeed, the quantum Hall effects are named after the tool by which they are most distinctly measured instead of the physics from which the phenomena originate. Here we report the first observation of a Hall effect in an ultracold gas of neutral atoms, revealed by measuring a Bose-Einstein condensate's transport properties perpendicular to a synthetic magnetic field. Our observations in this vortex-free superfluid are in good agreement with hydrodynamic predictions, demonstrating that the system's global irrotationality influences this superfluid Hall signal.


Assuntos
Temperatura Baixa , Magnetismo/métodos , Teoria Quântica , Semicondutores , Condutividade Elétrica , Elétrons , Estudos de Avaliação como Assunto , Hidrodinâmica
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