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1.
Phys Rev Lett ; 131(22): 222503, 2023 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-38101393

RESUMO

Isomers close to doubly magic _{28}^{78}Ni_{50} provide essential information on the shell evolution and shape coexistence near the Z=28 and N=50 double shell closure. We report the excitation energy measurement of the 1/2^{+} isomer in _{30}^{79}Zn_{49} through independent high-precision mass measurements with the JYFLTRAP double Penning trap and with the ISOLTRAP multi-reflection time-of-flight mass spectrometer. We unambiguously place the 1/2^{+} isomer at 942(10) keV, slightly below the 5/2^{+} state at 983(3) keV. With the use of state-of-the-art shell-model diagonalizations, complemented with discrete nonorthogonal shell-model calculations which are used here for the first time to interpret shape coexistence, we find low-lying deformed intruder states, similar to other N=49 isotones. The 1/2^{+} isomer is interpreted as the bandhead of a low-lying deformed structure akin to a predicted low-lying deformed band in ^{80}Zn, and points to shape coexistence in ^{79,80}Zn similar to the one observed in ^{78}Ni. The results make a strong case for confirming the claim of shape coexistence in this key region of the nuclear chart.

2.
Phys Rev Lett ; 118(16): 162502, 2017 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-28474931

RESUMO

A search for shape isomers in the ^{66}Ni nucleus was performed, following old suggestions of various mean-field models and recent ones, based on state-of-the-art Monte Carlo shell model (MCSM), all considering ^{66}Ni as the lightest nuclear system with shape isomerism. By employing the two-neutron transfer reaction induced by an ^{18}O beam on a ^{64}Ni target, at the sub-Coulomb barrier energy of 39 MeV, all three lowest-excited 0^{+} states in ^{66}Ni were populated and their γ decay was observed by γ-coincidence technique. The 0^{+} states lifetimes were assessed with the plunger method, yielding for the 0_{2}^{+}, 0_{3}^{+}, and 0_{4}^{+} decay to the 2_{1}^{+} state the B(E2) values of 4.3, 0.1, and 0.2 Weisskopf units (W.u.), respectively. MCSM calculations correctly predict the existence of all three excited 0^{+} states, pointing to the oblate, spherical, and prolate nature of the consecutive excitations. In addition, they account for the hindrance of the E2 decay from the prolate 0_{4}^{+} to the spherical 2_{1}^{+} state, although overestimating its value. This result makes ^{66}Ni a unique nuclear system, apart from ^{236,238}U, in which a retarded γ transition from a 0^{+} deformed state to a spherical configuration is observed, resembling a shape-isomerlike behavior.

3.
Phys Rev Lett ; 109(9): 092503, 2012 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-23002828

RESUMO

The 02(+) state in 34Si has been populated at the GANIL-LISE3 facility through the ß decay of a newly discovered 1(+) isomer in 34Al of 26(1) ms half-life. The simultaneous detection of e(+)e(-) pairs allowed the determination of the excitation energy E(02(+))=2719(3) keV and the half-life T(1/2)=19.4(7) ns, from which an electric monopole strength of ρ(2)(E0)=13.0(0.9)×10(-3) was deduced. The 2(1)(+) state is observed to decay both to the 0(1)(+) ground state and to the newly observed 0(2)(+) state [via a 607(2) keV transition] with a ratio R(2(1)(+)→0(1)(+)/2(1)(+)→0(2)(+))=1380(717). Gathering all information, a weak mixing with the 0(1)(+) and a large deformation parameter of ß=0.29(4) are found for the 0(2)(+) state, in good agreement with shell model calculations using a new SDPF-U-MIX interaction allowing np-nh excitations across the N=20 shell gap.

4.
Regul Pept ; 62(1): 53-61, 1996 Apr 09.
Artigo em Inglês | MEDLINE | ID: mdl-8738883

RESUMO

Natriuretic peptides and their receptors were characterized in rat submaxillary glands (SGs). Reverse phase-high performance liquid chromatography (HPLC) of rat SGs extracts revealed the presence of the 28-amino-acid (AA) circulating peptide ANP (Ser99-Tyr126) and the 126-AA prohormone (Asn1-Tyr126). The presence of ANP prohormone indicated that SGs are a site of ANP synthesis. Indeed, ANP mRNAs were demonstrated. ANP mRNA was 10 times lower than in the lung and only about 7 times lower than in the hypothalamus. ANP content in SG was determined as 30 +/- 8 ng/mg of protein (n = 7). In addition the presence of another member of the natriuretic peptide family, C-type natriuretic peptide (CNP), was found in SG. The CNP level of 293 +/- 38 pg/mg protein was significantly higher than in the lungs (44 +/- 6 pg/mg protein, P < 0.001, n = 5), but about 15 times lower than in hypothalamus (4.5 +/- 0.6 ng/mg protein, P < 0.001, n = 6). Both guanylyl cyclase and clearance receptors were expressed in SG. The presence of natriuretic peptide transcripts and their receptors suggests a role in rat SG functions.


Assuntos
Fator Natriurético Atrial/metabolismo , Proteínas/metabolismo , Glândula Submandibular/metabolismo , Animais , Fator Natriurético Atrial/química , Fator Natriurético Atrial/genética , Fator Natriurético Atrial/isolamento & purificação , Sequência de Bases , Cromatografia Líquida de Alta Pressão , Feminino , Hipotálamo/metabolismo , Dados de Sequência Molecular , Peptídeo Natriurético Tipo C , Reação em Cadeia da Polimerase , Proteínas/química , Proteínas/genética , Proteínas/isolamento & purificação , RNA Mensageiro/genética , RNA Mensageiro/metabolismo , Ratos , Ratos Sprague-Dawley , Receptores do Fator Natriurético Atrial/genética , Receptores do Fator Natriurético Atrial/metabolismo , Transcrição Gênica/genética
6.
Prim Care ; 13(1): 157-67, 1986 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-2869536

RESUMO

Patients with psychiatric problems are commonly encountered in the office setting. In this article, issues with which the primary care physician is likely to be confronted at some time are presented, with consideration given to suicidal and violent patients, organic brain syndromes, and psychopharmacologic issues. Practical principles of management applicable to the office are presented.


Assuntos
Intervenção em Crise , Transtornos Neurocognitivos/terapia , Transtornos Psicóticos/terapia , Suicídio , Adolescente , Adulto , Idoso , Antidepressivos Tricíclicos/efeitos adversos , Antipsicóticos/efeitos adversos , Benzodiazepinas/efeitos adversos , Interações Medicamentosas , Emergências , Medicina de Família e Comunidade , Feminino , Humanos , Lítio/efeitos adversos , Masculino , Pessoa de Meia-Idade , Inibidores da Monoaminoxidase/efeitos adversos , Psicoses Alcoólicas/terapia , Psicoses Induzidas por Substâncias/terapia , Estupro , Risco , Violência
7.
J Clin Psychiatry ; 46(11): 475-8, 1985 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-2865251

RESUMO

The efficacy of oral concentrate in the rapid tranquilization of 159 acutely disturbed patients in a psychiatric emergency service was evaluated. Patients were randomly assigned to 1 of 10 treatment groups: 7 oral groups and 3 comparison intramuscular groups. Although intramuscular medication produced a faster response, concentrate also proved to be effective for rapid tranquilization. Side effects were benign and minimal. Age, sex, race, and diagnosis had no effect on outcome. The use of concentrate as a paradigm for treating acutely psychotic patients is discussed.


Assuntos
Antipsicóticos/administração & dosagem , Transtornos Psicóticos/tratamento farmacológico , Doença Aguda , Administração Oral , Adolescente , Adulto , Idoso , Esquema de Medicação , Serviços de Emergência Psiquiátrica , Feminino , Haloperidol/administração & dosagem , Humanos , Injeções Intramusculares , Masculino , Pessoa de Meia-Idade , Escalas de Graduação Psiquiátrica , Transtornos Psicóticos/psicologia , Tioridazina/administração & dosagem , Tiotixeno/administração & dosagem , Fatores de Tempo
12.
Prensa méd. argent ; 57(13): 609-13, 1970 May 29.
Artigo em Espanhol | BINACIS | ID: bin-43110
13.
Prensa méd. argent ; 57(13): 609-13, 1970 May 29.
Artigo em Espanhol | LILACS-Express | BINACIS | ID: biblio-1168093
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