[Evaluation of the results of treatment of patients with functional dysphonia using a cepstral test]. / Otsenka rezul'tatov lecheniya patsientov s funktsional'noi disfoniei s pomoshch'yu kepstral'nogo testa.

In order to evaluate the effectiveness of the treatment in patients with functional dysphonia, the Cepstral Peak Prominence (CPP) test was used. Twenty dysphonic women aged from 18 to 47 years were under observation. The control group consisted of 20 healthy women of close age. Patients underwent 5-7 sessions electrostimulation of laryngeal muscles and phonopedic treatment, after which a complete restoration of the voice was noted. The Praat clinical program was used, installed on a Hewlett-Packard 630 laptop (Pentium B960, 2.2 GHz). A SHURE SM94 condenser microphone was used as well. In the control group, the results were as follows: M=7.49 (SD=1.26) dB. In the main group before treatment: M=5.00 (SD=1.07) dB, after treatment: M=7.95 (SD=1.34) dB. Differences in KT values in the main group before and after treatment (5.00 dB and 7.95 dB, respectively) were significant at p<0.0001. Differences in KT values in the main group before treatment (5.00 dB) and in the control group (7.49 dB) were significant at p<0.0001. Differences in KT values in the main group after treatment (7.95 dB) and in the control group (7.49 dB) were not significant at p>0.05. The study showed high sensitivity of the method. The CPP data after treatment were higher than those before treatment and did not differ from the control ones. It is concluded that CPP is a highly sensitive method for evaluating the degree of periodicity of an acoustic signal and can be used to evaluate the effectiveness of treatment in patients with functional dysphonia.

[FROM "CAPRICE MEDICINE" TO "EQUAL RESPONSIBILITY MEDICINE": TASKS, TECHNOLOGIES AND SPECIFICS OF CONFLICT MANAGEMENT IN A MULTIDISCIPLINARY PRIVATE CLINIC].

The article substantiates the tasks of introducing a conflict management system into the work of a private sector medical organization, reducing the number of ethical and legal conflicts that arise during the provision of medical care. The analysis of the conceptual foundations, regulatory framework and specifics of the use of conflict management tools in the context of solving organizational and managerial tasks in a private multidisciplinary clinic is presented.

[The analytical review of normative and organizational support of functioning of perinatal service in The Russian Federation in 2000-2020].

The formation of code of normative legal documents ensuring activities of perinatal service is one of the most important, basic organizational technologies that determine activities of obstetrics and childhood services, contributing to increasing of natality, decreasing of maternal and infant morbidity, and maternal and childhood health care in general. The article presents analysis of formation of normative legal base that regulates functioning of perinatal service in the Russian Federation in 2000-2020. Actually, there is no objective prerequisites for fundamental alterations in the three-level system of medical care of women during pregnancy, labor, postpartum period and newborns. However, the regulatory adjustment of the system, improvement and refinement of models of profile patients' routing, development of medical care of pregnant women, parturient women and puerpera will proceed.

[On the Methodology of Studying Organizational Technologies of Health Preservation].

The article considers methodological studying of problematics of health preservation and its organizational technologies. The health preservation is considered in the context of public health policy. The necessity of complex interdisciplinary and longitudinal approach to studying this problematic is substantiated. The results of analysis of semantics of key concepts of health preservation are presented. The patient-centralized principles of activities and communication as applied to health preservation are substantiated. The differentiation between concepts of "value" and "utility" of organizational technologies of health preservation for health are discussed. The possible areas of studying positioning of health preservation in the system of personality values, including health culture, are proposed. The possible structuration of factors determining health condition and healthy life-style are proved. The scope of principles and approaches for subsequent elaboration of methods, standards, instruments and regulations of complex methodology of studying issues of health preservation and its organizational technologies are established.

[The medical ethical aspects of organization of medical rehabilitation].

The article considers such aspects of organization of medical rehabilitation care of population as accessibility, quality, social efficiency from perspective of medical ethics. The quality of diagnostic, prevention and treatment of diseases is affected by qualification of medical personnel that is applied both to areas of clinical medicine and health care management. The specialists are to apply common principles and standards of health care. Among them are support of valuable quality of medical care under optimal application of available resources and observance of medical ethics standards. The Republic of Dagestan is anagrarian region where 55% of population resides in rural area and most of health care resources are cumulated in urban area. The indices of health of population residing in rural area are in many parameters worse than in urban population and provision of medical institutions with medical personnel is low. The specialized medical care support including medical rehabilitation, of rural population, is provided without additional managerial decisions and is much more difficult as compared with patients residing in urban area. Hence in conditions of necessity of optimization of resource support of health care system functioning no extensive development of possibilities of medical rehabilitation is possible in rural residents of Dagestan.

[The gas chromatography detection of fat acids in dry blood serum].

The article discusses the development of gas chromatography method of detecting the composition of fat acids in dry blood serum. The comparative analysis of content of fat acids in freshly selected and dry serum. The stability of composition of fat acids in dry serum under its conservation during 2 months was examined. It is demonstrated that qualitative and quantitative compound of fat acids in fresh and dry serum is identical and continue to be unchanged during one month.

[Improvement of method for detecting volatile fatty acids in air].

The authors demonstrated possible use of capillary columns to detect volatile fatty acids in air. Tenax TA as adsorbent is recommended.

[Cancer risk assessment in a group of traffic officers].

Air-pollution studies in the area where the traffic officers of the road-patrol service of the State Inspectorate for Road Traffic Safety, who patrol road traffic safety, breathe at the stationary militia inspection stations (MIS) and in the areas of the heaviest motor traffic highways of a city ascertained the cancer risk from exposure to carcinogenic agents, such as benzo(a)pyrene, benzene, and formaldehyde. The mean concentrations of these substances do not exceed the hygienic limits. In terms of the hazard index (1.04) and the individual's cancer risk index (4.8 x 10(-5)), the cancer risk for the traffic officers of MIS may be considered acceptable. Both indices (1.28 and 1.3 x 10(-4), respectively) for traffic officers and traffic controllers are suggestive of an increased cancer risk, which constitutes a potential threat to a rise in cancer morbidity in this occupational group and needs preventive measures to be undertaken.

[The provision of accessibility of ophthalmological care in medical organizations of various forms of property].

The article discusses the issues of provision of accessibility of ophthalmological care to population. The various differences in the implementation of constitutional principle of medical care accessibility in medical institutions of public and private property are introduced. Certain modern organizational technologies of provision of informational, financial and other forms of accessibility of qualitative medical care to citizen are determined.

[Sanitary and chemical control over workplace air in production of acrylic acid and its aethers].

The authors specified highly sensitive method based on capillary gas chromatography to detect acryl compounds in workplace air. The method is designed for industrial laboratories assessing quality of workplace air in acrylic acid and its aethers production.

[Age dymamics of stable chromosome aberration frequency in humans with natural and pathological senescence]. / Vozrastnaia dinamika chastoty stabil'nykh khromosomnykh aberratsii u cheloveka pri estestvennom i patologicheskom starenii.

The age dynamics of stable chromosome aberration (SCA) frequency was analysed by fluorescent in situ hybridization (FISH) in human blood lymphocytes derived from donors, irradiated by low doses of ionizing radiation (Chernobyl clean-up workers, nuclear weapon testers, etc.) and patients with hereditary premature aging--Werner's syndrome and Hutchinson-Gilford's syndrome. It was found that the level of SCA was age-dependent and increased in irradiated persons. So, the SCA level may be really an index of a so-called "radiation senescence", and may show a real biological age of irradiated persons. The patients with Werner's syndrome demonstrate increased SCA level in blood lymphocytes, corresponding to the premature aging of the organisms. But in the case of another form of premature aging--Hutchinson--Gilford's syndrome-- no rise of SCA level was found. Some possible reasons of such results are discussed.

[Modeling of normative and legal acts within the health care system]. / K voprosu o model'noi razrabotke normativno-pravovykh aktov v sisteme zdravookhraneniia.

The article deals with the issues of conceptual and methodological motivation of stages related with working out and approving the draft projects of regional healthcare legislation through superpositioning the legislative activity of the subjects of the Russian Federation on the provisions of the basic law "On Healthcare". The common features of the basic law are described; the specificity of the recommended structure and item-by-item sequence of principles and norms of regional laws "On Healthcare" is defined.

[Floating cell cultures of the fetal pancreas]. / Flotiruiuschchie kul'tury kletok podzheludochnoi zhelezy ploda.

A simple method for preparing human and animal fetal pancreatic cell cultures has been developed. It is based on enzymatic treatment of the fetal pancreatic tissue with collalitine in combination with microdissection. As a result of subsequent cultivation there form floating cytotypic and organotypic cultures consisting mainly of B cells in different phases of the secretory cycle. The floating cultures prepared by the above-described method produce insulin and can be successfully used in experimental and clinical transplantology.