1.
J Neuroimmunol
; 48(1): 71-9, 1993 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8227309
RESUMO
Using monoclonal antibodies to the three known human leukocyte IgG receptors, Fc gamma R, we examined the expression of Fc gamma R in normal brains and in Alzheimer's disease. We found Fc gamma RI, II and III immunoreactivity in senile plaques and on ramified microglia throughout the cortex and white matter of normal and Alzheimer's disease brains. Fc gamma RI expression was independently confirmed by a murine isotype binding study. These findings suggest that intrinsic Fc gamma R may play an important role in normal and disordered immune-related processes in the brain. They support the idea that microglia are brain macrophages.
Assuntos
Doença de Alzheimer/imunologia , Encéfalo/imunologia , Microglia/imunologia , Receptores de IgG/análise , Adulto , Animais , Anticorpos Monoclonais/imunologia , Linhagem Celular , Criança , Humanos , Imunoglobulina G/classificação , Imunoglobulina G/metabolismo , Camundongos , Receptores de IgG/fisiologia
2.
Riv Ist Sieroter Ital
; 43(2): 82-90, 1968.
Artigo
em Italiano
| MEDLINE
| ID: mdl-4176768
3.
Riv Ist Sieroter Ital
; 43(2): 59-63, 1968.
Artigo
em Italiano
| MEDLINE
| ID: mdl-4301112
4.
Riv Ist Sieroter Ital
; 43(2): 64-72, 1968.
Artigo
em Italiano
| MEDLINE
| ID: mdl-5693777
5.
Riv Ist Sieroter Ital
; 43(1): 29-35, 1968.
Artigo
em Italiano
| MEDLINE
| ID: mdl-5752689