RESUMO
The increasing levels of resistance of enteropathogenic bacteria against antimicrobial agents present geographic variations. We have analysed the antimicrobial susceptibility of isolates obtained from 4,364 children under 5 years of age with acute diarrhea, in 7 cities of Argentina. Diarrheagenic E. coli exhibited 74.5% of resistance against ampicillin, 64.2% against sulfametoxazole-trimethoprim, and Shigella spp., 62% and 75.6% respectively. Salmonella sp. showed 35%, 14%, 41.8%, 65.4%, 14.5%, and 13.6% of resistance against ampicillin, chloranfenicol, sulfametoxazole-trimetoprim, sulfadiazin, gentamycin, and fosfomycin respectively. These values are higher than the ones observed in developed countries. Aeromonas showed significantly lower resistance percentage. Important differences in our country were observed, consequently, local trials should be carried out in order to apply corrective measures.
Assuntos
Aeromonas/efeitos dos fármacos , Diarreia/microbiologia , Resistência Microbiana a Medicamentos , Enterobacteriaceae/efeitos dos fármacos , Infecções por Bactérias Gram-Negativas/microbiologia , Doença Aguda , Aeromonas/isolamento & purificação , Argentina/epidemiologia , Pré-Escolar , Diarreia/epidemiologia , Diarreia Infantil/epidemiologia , Diarreia Infantil/microbiologia , Disenteria Bacilar/epidemiologia , Disenteria Bacilar/microbiologia , Enterobacteriaceae/isolamento & purificação , Escherichia coli/efeitos dos fármacos , Escherichia coli/isolamento & purificação , Infecções por Escherichia coli/epidemiologia , Infecções por Escherichia coli/microbiologia , Feminino , Infecções por Bactérias Gram-Negativas/epidemiologia , Humanos , Lactente , Masculino , Testes de Sensibilidade Microbiana , Salmonella/efeitos dos fármacos , Salmonella/isolamento & purificação , Infecções por Salmonella/epidemiologia , Infecções por Salmonella/microbiologia , Shigella/efeitos dos fármacos , Shigella/isolamento & purificação , População UrbanaRESUMO
beta-Lactamases with pIs of 5.4 and 8.1 were detected by hydrolysis of ampicillin and ceftriaxone respectively among cefotaxime resistant serovars of Salmonella spp. suggesting TEM-1 and an unidentified extended spectrum beta-lactamase have spread throughout these strains in Argentina.
Assuntos
Cefotaxima/farmacologia , Resistência às Cefalosporinas , Cefalosporinas/farmacologia , Salmonella/efeitos dos fármacos , Ampicilina/metabolismo , Argentina , Ceftriaxona/metabolismo , Eletroforese , Humanos , Ponto Isoelétrico , Testes de Sensibilidade Microbiana , Salmonella/enzimologia , Infecções por Salmonella/microbiologia , beta-Lactamases/química , beta-Lactamases/metabolismoRESUMO
A total of 49 serotypes were isolated in Argentina during the triennium 1979-1981, from 3,665 Salmonella strains isolated from different sources: human, animal, food and water. The degree of correlation among every one of them was analyzed in order to establish their influence in the cycles of transmission and human infection. S. typhimurium prevailed in human materials, being also isolated from water and animal, although in a smaller degree. Something similar occurred with S. oranienburg. It was observed that S. typhi retained its usual feature of endemic disease. Other serotypes of Salmonella were also found, particularly: S. paratyphi, S. panama, S. derby, S. agona, S. bredeney, S. newport, S. anatum and S. montevideo. From 3,665 Salmonella strains studied, 73.73% were isolated from human sources and the other 26.27% from non human sources, 5.40% corresponding to animal isolations, 15.39% from water and 5.48% from food.
Assuntos
Salmonella/isolamento & purificação , Animais , Argentina , Contaminação de Alimentos , Microbiologia de Alimentos , Humanos , Salmonella/classificação , Infecções por Salmonella/microbiologia , Salmonelose Animal/microbiologia , Especificidade da Espécie , Microbiologia da ÁguaRESUMO
En la Republica Argentina, durante el trienio 1979-1982, se aislaron 49 serotipos de Salmonella a partir de 3.665 cepas correspondientes a distintas fuentes. Se trato de establecer la relacion de cada una de ellas en los ciclos de transmision e infeccion humana. S. typhimurium continua ocupando un lugar de prevalencia en las muestras humanas aislandose tambien de otras fuentes, principalmente agua y animales aunque en menor proporcion, ocurriendo algo similar con S. oranienburg.Con respecto a S. typhi, se observa que mantiene su habitual caracteristica de endemicidad en nuestro pais. Se encontraron otros serotipos de Salmonella, entre ellos S. paratyphi, S. panama, S. derby S. agona S. bredeney, S. newport, S. anatum y S.montevideo. De las 3.665 cepas de Salmonella estudiadas, el 73,73% proviene de fuentes humanas y el 26,27% restantes de fuentes no humanas, correpondiendo 5,40% a aislamientos en animales, 15,39% en agua y 4,58% en alimentos. Se destaca la necesidad de intensificar estudios de los diferentes eslabones que constituyen la cadena de infeccion por Salmonella
Assuntos
Humanos , Animais , Salmonella , Infecções por Salmonella , SorotipagemRESUMO
A total of 49 serotypes were isolated in Argentina during the triennium 1979-1981, from 3,665 Salmonella strains isolated from different sources: human, animal, food and water. The degree of correlation among every one of them was analyzed in order to establish their influence in the cycles of transmission and human infection. S. typhimurium prevailed in human materials, being also isolated from water and animal, although in a smaller degree. Something similar occurred with S. oranienburg. It was observed that S. typhi retained its usual feature of endemic disease. Other serotypes of Salmonella were also found, particularly: S. paratyphi, S. panama, S. derby, S. agona, S. bredeney, S. newport, S. anatum and S. montevideo. From 3,665 Salmonella strains studied, 73.73
were isolated from human sources and the other 26.27
from non human sources, 5.40
corresponding to animal isolations, 15.39
from water and 5.48
from food.
RESUMO
En la Republica Argentina, durante el trienio 1979-1982, se aislaron 49 serotipos de Salmonella a partir de 3.665 cepas correspondientes a distintas fuentes. Se trato de establecer la relacion de cada una de ellas en los ciclos de transmision e infeccion humana. S. typhimurium continua ocupando un lugar de prevalencia en las muestras humanas aislandose tambien de otras fuentes, principalmente agua y animales aunque en menor proporcion, ocurriendo algo similar con S. oranienburg.Con respecto a S. typhi, se observa que mantiene su habitual caracteristica de endemicidad en nuestro pais. Se encontraron otros serotipos de Salmonella, entre ellos S. paratyphi, S. panama, S. derby S. agona S. bredeney, S. newport, S. anatum y S.montevideo. De las 3.665 cepas de Salmonella estudiadas, el 73,73% proviene de fuentes humanas y el 26,27% restantes de fuentes no humanas, correpondiendo 5,40% a aislamientos en animales, 15,39% en agua y 4,58% en alimentos. Se destaca la necesidad de intensificar estudios de los diferentes eslabones que constituyen la cadena de infeccion por Salmonella