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1.
Radiats Biol Radioecol ; 44(4): 438-41, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15455674

RESUMO

It was shown that UV-irradiation caused damage to mice peritoneal macrophage plasma membranes. A decrease in extracellular Ca2+ leads to a decrease of the damaging effect. An increase in extracellular Ca2+ or adding of calcium ionophore A23187 to the medium is accompanied by an increase in a number of damaged cells. These data allow us to suppose that modification of the damaging effect of UV-irradiation by Ca2+ ions can be bound with changing of electric stability of membrane lipid matrix.


Assuntos
Cálcio/farmacologia , Macrófagos Peritoneais/efeitos dos fármacos , Macrófagos Peritoneais/efeitos da radiação , Raios Ultravioleta , Animais , Membrana Celular/efeitos dos fármacos , Membrana Celular/efeitos da radiação , Camundongos
2.
Radiats Biol Radioecol ; 44(4): 442-4, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15455675

RESUMO

It was detected that exposure of macrophages to red light (600-740 nm) led to the changes in their intracellular pH and hydrolytic activity. The character of these changes depends on the initial level of pH in the cells. The maximum effect of irradiation is detected if the initial pH level is low. It is possible that Na/H-exchanger takes part in normalizing effect of red light on intracellular pH level.


Assuntos
Concentração de Íons de Hidrogênio , Luz , Macrófagos Peritoneais/efeitos da radiação , Animais , Macrófagos Peritoneais/citologia , Macrófagos Peritoneais/metabolismo , Camundongos , Trocadores de Sódio-Hidrogênio/metabolismo
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