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Nuklearmedizin ; 45(4): 160-2, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16964341

RESUMO

AIM: Somatostatin receptor scintigraphy images various neoplastic, granulomatous, and auto-immune diseases. Cat-scratch disease in an infectious granulomatous disease usually affecting the lymphnodes. It is not known whether cat-scratch disease provides positive somatostatin receptor scintigrams. PATIENTS, METHODS: Twelve patients with lymphadenitis and suspected cat-scratch disease were investigated by immunofluorescence antibody testing and somatostatin receptor scintigraphy. Suppurated lymphnodes were extracted or drained and Bartonella henselae specific PCR was then performed. RESULTS: Eleven of 12 patients showed IgG antibodies against B. henselae. SRS showed positive scintigraphic results in 6 of 11 patients with CSD. B. henselae DNA was detected in tissue of lymphnodes from 4 of 5 patients with lymphnode extraction or lymphnode drainage. SRS demonstrated positive scintigrams in all patients with a positive PCR. In one patient with suspected CSD SRS was negative as well as antibody testing. CONCLUSION: Somatostatin receptor scintigraphy correlated with positive Bartonella henselae specific PCR tests and positive Bartonella henselae specific antibody tests in patients with CSD.


Assuntos
Doença da Arranhadura de Gato/complicações , Linfadenite/diagnóstico por imagem , Receptores de Somatostatina/análise , Animais , Portador Sadio , Doença da Arranhadura de Gato/transmissão , Gatos , Humanos , Linfadenite/etiologia , Reação em Cadeia da Polimerase/métodos , Cintilografia , Receptores de Somatostatina/genética , Testes Cutâneos/efeitos adversos
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