RESUMO
A chimpanzee of simian-type blood groups V.A, cef, G, H, L was isoimmunized with the red cells of another chimpanzee of simian-type V.B, cef, G, H, 1 in order to obtain antibodies of specificity anti-Bc, originally produced in another chimpanzee in 1964. In addition to the desired anti-Bc, the immunized chimpanzee produced also three other antibodies; anti-Yc cross-reactive with chimpanzee red cells of the simian-type Bc and/or Dc, a potent cold autoantibody reactive for red cells of all chimpanzees tested, and 'new' antibodies anti-Oc and anti-Pc. This study confirms the reproducibility of results obtained over a period of 13 years.
Assuntos
Antígenos de Grupos Sanguíneos , Pan troglodytes/imunologia , Animais , Formação de Anticorpos , Reações Cruzadas , Eritrócitos/imunologia , Gorilla gorilla/imunologia , Soros Imunes , Imunização , Imunogenética , Macaca mulatta/imunologia , MasculinoRESUMO
The human-type A-B-O blood groups of 52 bonnet macaques (Macaca radiata) were determined. Application of method of population genetics indicated the gene frequences to be 0 = 0.173, a = 0.480 and B = 0.347. Cross testing of sera and red cells of the bonnet macaques revealed two blood-type-specific isoagglutinins, one of them strong enough for use as a blood typing reagent. No blood group polymorphism was revealed by testing bonnet macaque red cells with isoantisera produced in rhesus monkeys (M. mulatta) and in crab-eating macaques (M. fascicularis). The rhesus and crab-eating macaque isoantisera reacted either with all or with none of the bonnet macaque red cells tested.